Daniel Khananshvili

Department of Physiology and Pharmacology, Tel Aviv University

Affiliated withTel Aviv University tel aviv university

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2017

Other Publications

Article	Year
Direct Loading of the purified endogenous inhibitor into the cytoplasm of patched cardiomyocytes blocks the ion currents and calcium transport through the NCX1 protein. Biochemistry\| PubMed ID: 18507397	2008
The endogenous inhibitor of NCX1 does not resemble the properties of digitalis compound. Biochemical and biophysical research communications\| PubMed ID: 12890488	2003
Inotropic and lusitropic effects induced by the inhibitory factor of the Na/Ca exchanger are not mediated by the beta-adrenergic activation. Journal of cardiovascular pharmacology\| PubMed ID: 15454855	2004
The low molecular weight inhibitor of NCX1 interacts with a cytosolic domain that differs from the ion-transport site of the Na/Ca exchanger. Biochemical and biophysical research communications\| PubMed ID: 15504362	2004
Advanced procedures for separation and analysis of low molecular weight inhibitor (NCXIF) of the cardiac sodium-calcium exchanger. Biochemical and biophysical research communications\| PubMed ID: 16226722	2005
Purified endogenous inhibitor of the Na/Ca exchanger can enhance the cardiomyocytes contractility and calcium transients. Biochemical and biophysical research communications\| PubMed ID: 16782052	2006
Single alpha-domain constructs of the Na+/Ca2+ exchanger, NCLX, oligomerize to form a functional exchanger. Biochemistry\| PubMed ID: 17002286	2006
Effects of purified endogenous inhibitor of the Na+/Ca2+ exchanger on ouabain-induced arrhythmias in the atria and ventricle strips of guinea pig. European journal of pharmacology\| PubMed ID: 17078946	2006
Kinetic and equilibrium properties of regulatory calcium sensors of NCX1 protein. The Journal of biological chemistry\| PubMed ID: 19141619	2009
NCLX is an essential component of mitochondrial Na+/Ca2+ exchange. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20018762	2010
Essential role of the CBD1-CBD2 linker in slow dissociation of Ca2+ from the regulatory two-domain tandem of NCX1. The Journal of biological chemistry\| PubMed ID: 20587421	2010
Proton-sensing Ca2+ binding domains regulate the cardiac Na+/Ca2+ exchanger. The Journal of biological chemistry\| PubMed ID: 21680748	2011
Dynamic features of allosteric Ca2+ sensor in tissue-specific NCX variants. Cell calcium\| PubMed ID: 22571864	2012
A common Ca2+-driven interdomain module governs eukaryotic NCX regulation. PloS one\| PubMed ID: 22768191	2012
G503 is obligatory for coupling of regulatory domains in NCX proteins. Biochemistry\| PubMed ID: 22924554	2012
The mitochondrial Na+/Ca2+ exchanger upregulates glucose dependent Ca2+ signalling linked to insulin secretion. PloS one\| PubMed ID: 23056385	2012
Molecular determinants of allosteric regulation in NCX proteins. Advances in experimental medicine and biology\| PubMed ID: 23224868	2013
The SLC8 gene family of sodium-calcium exchangers (NCX) - structure, function, and regulation in health and disease. Molecular aspects of medicine\| PubMed ID: 23506867	2013
NCLX: the mitochondrial sodium calcium exchanger. Journal of molecular and cellular cardiology\| PubMed ID: 23538132	2013
SK4 Ca2+ activated K+ channel is a critical player in cardiac pacemaker derived from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23589888	2013
Population shift underlies Ca2+-induced regulatory transitions in the sodium-calcium exchanger (NCX). The Journal of biological chemistry\| PubMed ID: 23798674	2013
The C2B domain is the primary Ca2+ sensor in DOC2B: a structural and functional analysis. Journal of molecular biology\| PubMed ID: 23994332	2013
Sodium-calcium exchangers (NCX): molecular hallmarks underlying the tissue-specific and systemic functions. Pflugers Archiv : European journal of physiology\| PubMed ID: 24281864	2014
Functional asymmetry of bidirectional Ca2+-movements in an archaeal sodium-calcium exchanger (NCX_Mj). Cell calcium\| PubMed ID: 25218934	2014
Structure-dynamic determinants governing a mode of regulatory response and propagation of allosteric signal in splice variants of Na+/Ca2+ exchange (NCX) proteins. The Biochemical journal\| PubMed ID: 25387769	2015
Sodium recognition by the Na+/Ca2+ exchanger in the outward-facing conformation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25468964	2014
Structure-dynamic basis of splicing-dependent regulation in tissue-specific variants of the sodium-calcium exchanger. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 26644350	2016
Asymmetric Preorganization of Inverted Pair Residues in the Sodium-Calcium Exchanger. Scientific reports\| PubMed ID: 26876271	2016
Structural Features of Ion Transport and Allosteric Regulation in Sodium-Calcium Exchanger (NCX) Proteins. Frontiers in physiology\| PubMed ID: 26903880	2016
Kinetic and equilibrium properties of regulatory Ca(2+)-binding domains in sodium-calcium exchangers 2 and 3. Cell calcium\| PubMed ID: 26924806	2016
Structure-Based Engineering of Lithium-Transport Capacity in an Archaeal Sodium-Calcium Exchanger. Biochemistry\| PubMed ID: 26958982	2016
Structure-Functional Basis of Ion Transport in Sodium-Calcium Exchanger (NCX) Proteins. International journal of molecular sciences\| PubMed ID: 27879668	2016
Purification and characterization of human dehydrodolychil diphosphate synthase (DHDDS) overexpressed in E. coli. Protein expression and purification\| PubMed ID: 28167250	2017
Structure-based dynamic arrays in regulatory domains of sodium-calcium exchanger (NCX) isoforms. Scientific reports\| PubMed ID: 28428550	2017
Dynamic distinctions in the Na(+)/Ca(2+) exchanger adopting the inward- and outward-facing conformational states. The Journal of biological chemistry\| PubMed ID: 28572509	2017
How a helix imposes palmitoylation of a membrane protein: What one can learn from NCX. The Journal of biological chemistry\| PubMed ID: 28646126	2017