Sharon C-A. Chen

Centre for Infectious Diseases and Microbiology-Public Health, Westmead hospital

Affiliated withWestmead hospital ICPMR The University of Sydney

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 22	2017

Other Publications

Article	Year
Cryptococcosis in Australasia and the treatment of cryptococcal and other fungal infections with liposomal amphotericin B. The Journal of antimicrobial chemotherapy\| PubMed ID: 11801583	2002
Strain-dependent effects of environmental signals on the production of extracellular phospholipase by Cryptococcus neoformans. FEMS microbiology letters\| PubMed ID: 12007802	2002
A review of nucleic acid-based diagnostic tests for systemic mycoses with an emphasis on polymerase chain reaction-based assays. Medical mycology\| PubMed ID: 12230214	2002
Cryptococcal phospholipases: a novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattii. The Biochemical journal\| PubMed ID: 15320865	2004
Cryptococcal phospholipase B antigen is not detected in serum of patients infected with Cryptococcus neoformans using a sandwich enzyme-linked immunosorbent assay. FEMS yeast research\| PubMed ID: 17266733	2007
In vitro activities of miltefosine and two novel antifungal biscationic salts against a panel of 77 dermatophytes. Antimicrobial agents and chemotherapy\| PubMed ID: 17371821	2007
Antifungal agents. The Medical journal of Australia\| PubMed ID: 17908006	2007
Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients. Antimicrobial agents and chemotherapy\| PubMed ID: 18212110	2008
Molecular typing of Australian Scedosporium isolates showing genetic variability and numerous S. aurantiacum. Emerging infectious diseases\| PubMed ID: 18258122	2008
Practical method for detection and identification of Candida, Aspergillus, and Scedosporium spp. by use of rolling-circle amplification. Journal of clinical microbiology\| PubMed ID: 18495860	2008
Genotyping of Scedosporium species: a review of molecular approaches. Medical mycology\| PubMed ID: 19085455	2009
Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients. Pediatrics\| PubMed ID: 19403503	2009
Assignment of Reference 5'-end 16S rDNA Sequences and Species-Specific Sequence Polymorphisms Improves Species Identification of Nocardia. The open microbiology journal\| PubMed ID: 19639036	2009
Identification of pathogenic Nocardia species by reverse line blot hybridization targeting the 16S rRNA and 16S-23S rRNA gene spacer regions. Journal of clinical microbiology\| PubMed ID: 19955277	2010
Comparison of whole blood, serum, and plasma for early detection of candidemia by multiplex-tandem PCR. Journal of clinical microbiology\| PubMed ID: 20042634	2010
Fungal-derived immune modulating molecules. Advances in experimental medicine and biology\| PubMed ID: 20054979	2009
Protein-losing enteropathy and hypogammaglobulinaemia as first manifestations of disseminated histoplasmosis coincident with Nocardia infection. Journal of medical microbiology\| PubMed ID: 20133412	2010
In vitro antifungal activities of bis(alkylpyridinium)alkane compounds against pathogenic yeasts and molds. Antimicrobial agents and chemotherapy\| PubMed ID: 20530227	2010
Antifungal therapy in invasive fungal infections. Current opinion in pharmacology\| PubMed ID: 20598943	2010
secA1 gene sequence polymorphisms for species identification of Nocardia species and recognition of intraspecies genetic diversity. Journal of clinical microbiology\| PubMed ID: 20810768	2010
New molecular and surrogate biomarker-based tests in the diagnosis of bacterial and fungal infection in febrile neutropenic patients. Current opinion in infectious diseases\| PubMed ID: 20827189	2010
Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors? Medical mycology\| PubMed ID: 21067328	2010
Scedosporium aurantiacum is as virulent as S. prolificans, and shows strain-specific virulence differences, in a mouse model. Medical mycology\| PubMed ID: 21067330	2010
Abundance of Pseudallescheria/Scedosporium species in the Australian urban environment suggests a possible source for scedosporiosis including the colonization of airways in cystic fibrosis. Medical mycology\| PubMed ID: 21067333	2010
Recent advances in management of cryptococcal meningitis: commentary. F1000 medicine reports\| PubMed ID: 21170376	2010
Echinocandin antifungal drugs in fungal infections: a comparison. Drugs\| PubMed ID: 21175238	2011
Development and validation of a multiplex PCR for detection of Scedosporium spp. in respiratory tract specimens from patients with cystic fibrosis. Journal of clinical microbiology\| PubMed ID: 21325557	2011
Fatal mycotic aneurysms due to Scedosporium and Pseudallescheria infection. Journal of clinical microbiology\| PubMed ID: 21430108	2011
Defining reference sequences for Nocardia species by similarity and clustering analyses of 16S rRNA gene sequence data. PloS one\| PubMed ID: 21687706	2011
Direct effects of non-antifungal agents used in cancer chemotherapy and organ transplantation on the development and virulence of Candida and Aspergillus species. Virulence\| PubMed ID: 21701255	2011
Identification of bacteria in blood culture broths using matrix-assisted laser desorption-ionization Sepsityper™ and time of flight mass spectrometry. PloS one\| PubMed ID: 21858058	2011
Three-locus identification, genotyping, and antifungal susceptibilities of medically important Trichosporon species from China. Journal of clinical microbiology\| PubMed ID: 21900517	2011
Matrix-assisted laser desorption ionization-time of flight mass spectrometry identification of yeasts is contingent on robust reference spectra. PloS one\| PubMed ID: 22022438	2011
Nosocomial Pneumocystis jirovecii pneumonia: lessons from a cluster in kidney transplant recipients. Transplantation\| PubMed ID: 22129760	2011
Seeking clarity within cloudy effluents: differentiating fungal from bacterial peritonitis in peritoneal dialysis patients. PloS one\| PubMed ID: 22145033	2011
Pneumonia and lung infections due to emerging and unusual fungal pathogens. Seminars in respiratory and critical care medicine\| PubMed ID: 22167398	2011
Sporotrichosis (Sporothrix schenckii infection) in the New South Wales mid-north coast, 2000-2010. The Medical journal of Australia\| PubMed ID: 22621152	2012
Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoring. Antimicrobial agents and chemotherapy\| PubMed ID: 22751544	2012
Multicenter study of posaconazole therapeutic drug monitoring: exposure-response relationship and factors affecting concentration. Antimicrobial agents and chemotherapy\| PubMed ID: 22890761	2012
In vitro susceptibilities of yeast species to fluconazole and voriconazole as determined by the 2010 National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) study. Journal of clinical microbiology\| PubMed ID: 23035204	2012
Clinical utility of the cryptococcal antigen lateral flow assay in a diagnostic mycology laboratory. PloS one\| PubMed ID: 23166705	2012
Current status of matrix-assisted laser desorption ionisation-time of flight mass spectrometry in the clinical microbiology laboratory. Pathology\| PubMed ID: 23255029	2013
Post-transplant Pneumocystis jirovecii pneumonia-a re-emerged public health problem? Kidney international\| PubMed ID: 23739237	2013
Rapid identification of Gram-negative organisms from blood culture bottles using a modified extraction method and MALDI-TOF mass spectrometry. Diagnostic microbiology and infectious disease\| PubMed ID: 23891220	2013
Fungal infections and treatment in cystic fibrosis. Current opinion in pulmonary medicine\| PubMed ID: 24060984	2013
A loop-mediated isothermal amplification (LAMP) assay for Strongyloides stercoralis in stool that uses a visual detection method with SYTO-82 fluorescent dye. The American journal of tropical medicine and hygiene\| PubMed ID: 24323513	2014
Thermomyces lanuginosus infective endocarditis: Case report and a review of endocarditis due to uncommon moulds. Medical mycology case reports\| PubMed ID: 24432243	2013
Echinocandins in the treatment of candidaemia and invasive candidiasis: clinical and economic perspectives. International journal of antimicrobial agents\| PubMed ID: 24670423	2014
Candida quercitrusa candidemia: investigation of three clustered cases and mycological characteristics of this novel species. Journal of clinical microbiology\| PubMed ID: 24696025	2014
Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects. Fungal genetics and biology : FG & B\| PubMed ID: 24731805	2014
Clinical utility of Aspergillus galactomannan and PCR in bronchoalveolar lavage fluid for the diagnosis of invasive pulmonary aspergillosis in patients with haematological malignancies. Diagnostic microbiology and infectious disease\| PubMed ID: 24768294	2014
Clinical utility of caspofungin eye drops in fungal keratitis. International journal of antimicrobial agents\| PubMed ID: 24933448	2014
Improved identification of rapidly growing mycobacteria by a 16S-23S internal transcribed spacer region PCR and capillary gel electrophoresis. PloS one\| PubMed ID: 25013955	2014
Detection of multiple fungal species in blood samples by real-time PCR: an interpretative challenge. Journal of clinical microbiology\| PubMed ID: 25143424	2014
Cystic fibrosis and bacterial colonization define the sputum N-glycosylation phenotype. Glycobiology\| PubMed ID: 25190359	2015
Rapid and accurate direct antibiotic susceptibility testing of blood culture broths using MALDI Sepsityper combined with the BD Phoenix automated system. Journal of medical microbiology\| PubMed ID: 25212759	2014
Cryptococcus gattii infections. Clinical microbiology reviews\| PubMed ID: 25278580	2014
Antifungal susceptibilities of Candida glabrata species complex, Candida krusei, Candida parapsilosis species complex and Candida tropicalis causing invasive candidiasis in China: 3 year nat... The Journal of antimicrobial chemotherapy\| PubMed ID: 25473027	2015
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans. PloS one\| PubMed ID: 25490199	2014
Rapid microscopy and use of vital dyes: potential to determine viability of Cryptococcus neoformans in the clinical laboratory. PloS one\| PubMed ID: 25625210	2015
Candida colonization as a risk marker for invasive candidiasis in mixed medical-surgical intensive care units: development and evaluation of a simple, standard protocol. Journal of clinical microbiology\| PubMed ID: 25673797	2015
Invasive infections due to filamentous fungi other than Aspergillus: epidemiology and determinants of mortality. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases\| PubMed ID: 25677259	2015
Contemporary molecular approaches in the clinical microbiology laboratory: progress and pitfalls. Pathology\| PubMed ID: 25714589	2015
Colonisation with Pneumocystis jirovecii in Australian infants. Pathology\| PubMed ID: 25938363	2015
Evaluation of point-of-care testing in critically unwell patients: comparison with clinical laboratory analysers and applicability to patients with Ebolavirus infection. Pathology\| PubMed ID: 26126049	2015
Editorial: Laboratory preparedness for Ebolavirus disease. Pathology\| PubMed ID: 26126052	2015
What assay is optimal for the diagnosis of measles virus infection? An evaluation of the performance of a measles virus real-time reverse transcriptase PCR using the Cepheid SmartCycler(®) a... Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 26305819	2015
Antibiotic susceptibility of diverse Mycobacterium abscessus complex strains in New South Wales, Australia. Pathology\| PubMed ID: 26517625	2015
Accurate Identification of Common Pathogenic Nocardia Species: Evaluation of a Multilocus Sequence Analysis Platform and Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spect... PloS one\| PubMed ID: 26808813	2016
Chaetomium atrobrunneum and Aspergillus fumigatus in multiple tracheal aspirates: Copathogens or symbiosis. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi\| PubMed ID: 26880338	2016
Concordance of four commercial enzyme immunoassay and three immunoblot formats for the detection of Lyme borreliosis antibodies in human serum: the two-tier approach remains. Pathology\| PubMed ID: 27020501	2016
Sequencer-Based Capillary Gel Electrophoresis (SCGE) Targeting the rDNA Internal Transcribed Spacer (ITS) Regions for Accurate Identification of Clinically Important Yeast Species. PloS one\| PubMed ID: 27105313	2016
Performance of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of Aspergillus, Scedosporium, and Fusarium spp. in the Australian Clinical Sett... Journal of clinical microbiology\| PubMed ID: 27252460	2016
Successful treatment of Cryptococcus neoformans immune reconstitution inflammatory syndrome in an immunocompetent host using thalidomide. Medical mycology case reports\| PubMed ID: 27330941	2015
Safety, clinical effectiveness and trough plasma concentrations of intravenous posaconazole in patients with haematological malignancies and/or undergoing allogeneic haematopoietic stem cell... The Journal of antimicrobial chemotherapy\| PubMed ID: 27521358	2016
Identification and Antifungal Susceptibility Profiles of Candida haemulonii Species Complex Clinical Isolates from a Multicenter Study in China. Journal of clinical microbiology\| PubMed ID: 27535688	2016
Antifungal susceptibilities of non-Aspergillus filamentous fungi causing invasive infection in Australia: support for current antifungal guideline recommendations. International journal of antimicrobial agents\| PubMed ID: 27562696	2016
Mycological testing of clinical samples in Australasian pathology laboratories: wide diversity and room for improvement. Pathology\| PubMed ID: 27567987	2016
Problematic Dichotomization of Risk for Intensive Care Unit (ICU)-Acquired Invasive Candidiasis: Results Using a Risk-Predictive Model to Categorize 3 Levels of Risk From a Multicenter Prosp... Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 27601224	2016
16S-23S Internal Transcribed Spacer Region PCR and Sequencer-Based Capillary Gel Electrophoresis has Potential as an Alternative to High Performance Liquid Chromatography for Identification ... PloS one\| PubMed ID: 27749897	2016
Verruconis gallopava cardiac and endovascular infection with dissemination after renal transplantation: Case report and lessons learned. Medical mycology case reports\| PubMed ID: 28053851	2017
Transcriptome and network analyses in Saccharomyces cerevisiae reveal that amphotericin B and lactoferrin synergy disrupt metal homeostasis and stress response. Scientific reports\| PubMed ID: 28079179	2017
Identification and Antifungal Susceptibility Profiles of Candida nivariensis and Candida bracarensis in a Multi-Center Chinese Collection of Yeasts. Frontiers in microbiology\| PubMed ID: 28154553	2017
New developments and directions in the clinical application of the echinocandins. Archives of toxicology\| PubMed ID: 28180946	2017
Laboratory Approach to the Diagnosis of Culture-Negative Infective Endocarditis. Heart, lung & circulation\| PubMed ID: 28372886	2017
Pseudomonas aeruginosa Inhibits the Growth of Scedosporium and Lomentospora In Vitro. Mycopathologia\| PubMed ID: 28512704	2017
Molecular Epidemiology and Antifungal Susceptibility of Candida glabrata in China (August 2009 to July 2014): A Multi-Center Study. Frontiers in microbiology\| PubMed ID: 28588560	2017
Challenges in Laboratory Detection of Fungal Pathogens in the Airways of Cystic Fibrosis Patients. Mycopathologia\| PubMed ID: 28589247	2017
Locally Acquired mcr-1 in Escherichia coli, Australia, 2011 and 2013. Emerging infectious diseases\| PubMed ID: 28628439	2017
Genome sequencing links persistent outbreak of legionellosis in Sydney to an emerging clone of Legionella pneumophila ST211. Applied and environmental microbiology\| PubMed ID: 29247056	2017