Wen-Tsan Chang

The Institute of Basic Medical Sciences, National Cheng Kung University

Affiliated withNational Cheng Kung University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2018

Other Publications

Article	Year
The role of inducible nitric oxide synthase in a murine acute hepatitis B virus (HBV) infection model induced by hydrodynamics-based in vivo transfection of HBV-DNA. Journal of hepatology\| PubMed ID: 14568268	2003
Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage. Carcinogenesis\| PubMed ID: 15180947	2004
Disruption of the peroxisomal citrate synthase CshA affects cell growth and multicellular development in Dictyostelium discoideum. Molecular microbiology\| PubMed ID: 15225305	2004
Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramideand etoposide-induced apoptosis. The Journal of biological chemistry\| PubMed ID: 15262979	2004
Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinase. The Journal of biological chemistry\| PubMed ID: 15319438	2004
Streptococcal pyrogenic exotoxin B-induced apoptosis in a549 cells is mediated by a receptor- and mitochondrion-dependent pathway. Infection and immunity\| PubMed ID: 15557629	2004
Simple and efficient DNA vector-based RNAi systems in mammalian cells. Biochemical and biophysical research communications\| PubMed ID: 15781231	2005
Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation. The Journal of biological chemistry\| PubMed ID: 15817479	2005
LrrA, a novel leucine-rich repeat protein involved in cytoskeleton remodeling, is required for multicellular morphogenesis in Dictyostelium discoideum. Developmental biology\| PubMed ID: 16051212	2005
Therapeutic inhibition of hepatitis B virus surface antigen expression by RNA interference. Biochemical and biophysical research communications\| PubMed ID: 16153600	2005
Association of CD14 promoter polymorphisms and soluble CD14 levels in mite allergen sensitization of children in Taiwan. Journal of human genetics\| PubMed ID: 16292464	2006
A novel bidirectional expression system for simultaneous expression of both the protein-coding genes and short hairpin RNAs in mammalian cells. Biochemical and biophysical research communications\| PubMed ID: 16337609	2006
Toll-like receptor 4 plays an anti-HBV role in a murine model of acute hepatitis B virus expression. World journal of gastroenterology\| PubMed ID: 16425356	2005
A novel siRNA validation system for functional screening and identification of effective RNAi probes in mammalian cells. Biochemical and biophysical research communications\| PubMed ID: 16793020	2006
Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST. The Journal of biological chemistry\| PubMed ID: 17046825	2006
Deregulation of AP-1 proteins in collagen gel-induced epithelial cell apoptosis mediated by low substratum rigidity. The Journal of biological chemistry\| PubMed ID: 17085440	2007
A tightly regulated and reversibly inducible siRNA expression system for conditional RNAi-mediated gene silencing in mammalian cells. The journal of gene medicine\| PubMed ID: 17486668	2007
Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway. Blood\| PubMed ID: 18270325	2008
Construction of simple and efficient DNA vector-based short hairpin RNA expression systems for specific gene silencing in mammalian cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18314586	2007
Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway. International journal of cancer\| PubMed ID: 18623086	2008
Identification and characterization of the mitochondrial targeting sequence and mechanism in human citrate synthase. Journal of cellular biochemistry\| PubMed ID: 19479947	2009
Hepatitis B virus surface antigen interacts with acid alpha-glucosidase and alters glycogen metabolism. Hepatology research : the official journal of the Japan Society of Hepatology\| PubMed ID: 20618459	2010
Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical i... Molecular cancer\| PubMed ID: 21122157	2010
ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells. Journal of cellular biochemistry\| PubMed ID: 21328461	2011
Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy. Scientific reports\| PubMed ID: 23139858	2012
Propolis inhibits TGF-β1-induced epithelial-mesenchymal transition in human alveolar epithelial cells via PPARγ activation. International immunopharmacology\| PubMed ID: 23328619	2013
Upregulation of tissue factor by activated Stat3 contributes to malignant pleural effusion generation via enhancing tumor metastasis and vascular permeability in lung adenocarcinoma. PloS one\| PubMed ID: 24086497	2013
Construction of simple and efficient siRNA validation systems for screening and identification of effective RNAi-targeted sequences from mammalian genes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24233788	2014
Association between mechanical ventilation and neurodevelopmental disorders in a nationwide cohort of extremely low birth weight infants. Research in developmental disabilities\| PubMed ID: 24769371	2014
Effect of Size-Dependent Photodestructive Efficacy by Gold Nanomaterials with Multiphoton Laser. ACS applied materials & interfaces\| PubMed ID: 26172073	2015
Cyclic Stretch Facilitates Myogenesis in C2C12 Myoblasts and Rescues Thiazolidinedione-Inhibited Myotube Formation. Frontiers in bioengineering and biotechnology\| PubMed ID: 27047938	2016
Dynamic evolution of D-dimer level in cerebrospinal fluid predicts poor outcome in patients with spontaneous intracerebral hemorrhage combined with intraventricular hemorrhage. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia\| PubMed ID: 27050917	2016
Graphene quantum dots conjugated with polymers for two-photon properties under two-photon excitation. Nanoscale\| PubMed ID: 27722374	2016
Pterostilbene prevents AKT-ERK axis-mediated polymerization of surface fibronectin on suspended lung cancer cells independently of apoptosis and suppresses metastasis. Journal of hematology & oncology\| PubMed ID: 28327179	2017
Increased risk of brain cancer incidence in stroke patients: a clinical case series, population-based and longitudinal follow-up study. Oncotarget\| PubMed ID: 29312585	2017
Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer. International journal of molecular sciences\| PubMed ID: 29346311	2018
Decreased succinate dehydrogenase B in human hepatocellular carcinoma accelerates tumor malignancy by inducing the Warburg effect. Scientific reports\| PubMed ID: 29449614	2018
The decrease of glycolytic enzyme hexokinase 1 accelerates tumor malignancy via deregulating energy metabolism but sensitizes cancer cells to 2-deoxyglucose inhibition. Oncotarget\| PubMed ID: 29721175	2018