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JoVE Journal
Cancer Research

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The Establishment of a Lung Colonization Assay for Circulating Tumor Cell Visualization in Lung Tissues
 

The Establishment of a Lung Colonization Assay for Circulating Tumor Cell Visualization in Lung Tissues

Article doi: 10.3791/56761
June 16th, 2018

Summary June 16th, 2018

An animal model is needed to decipher the role of circulating tumor cells (CTCs) in promoting lung colonization during cancer metastasis. Here, we established and successfully performed an in vivo assay to specifically test the requirement of polymeric fibronectin (polyFN) assembly on CTCs for lung colonization.

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