Philipp Koch

Institute of Reconstructive Neurobiology, University of Bonn

Affiliated withUniversity of Bonn University of Heidelberg/Medical Faculty Mannheim Hector Institute for Translational Brain Research (HITBR gGmbH)

Research Area

Developmental Biology

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 43	2018

Other Publications

Article	Year
Nucleofection of human embryonic stem cells. Stem cells and development\| PubMed ID: 16137226	2005
Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase. Nature methods\| PubMed ID: 16721380	2006
Transduction of human embryonic stem cells by ecotropic retroviral vectors. Nucleic acids research\| PubMed ID: 16998181	2006
Nucleofection of human embryonic stem cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18370194	2008
Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons. Stem cells (Dayton, Ohio)\| PubMed ID: 18420830	2008
A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19218428	2009
Emerging concepts in neural stem cell research: autologous repair and cell-based disease modelling. The Lancet. Neurology\| PubMed ID: 19679274	2009
Laser-assisted photoablation of human pluripotent stem cells from differentiating cultures. Stem cell reviews\| PubMed ID: 20186504	2010
Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo. Stem cells (Dayton, Ohio)\| PubMed ID: 20235098	2010
Human embryonic stem cell-derived neurons establish region-specific, long-range projections in the adult brain. Cellular and molecular life sciences : CMLS\| PubMed ID: 21779868	2012
A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat. Acta neuropathologica\| PubMed ID: 21863243	2011
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease. Nature\| PubMed ID: 22113611	2011
Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons. PloS one\| PubMed ID: 22272239	2012
Small molecules enable highly efficient neuronal conversion of human fibroblasts. Nature methods\| PubMed ID: 22484851	2012
Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation. The American journal of pathology\| PubMed ID: 22510327	2012
Functional neuronal cells generated by human parthenogenetic stem cells. PloS one\| PubMed ID: 22880113	2012
Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma. Stem cells (Dayton, Ohio)\| PubMed ID: 23390110	2013
Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies. Nature reviews. Molecular cell biology\| PubMed ID: 23486282	2013
Embryonic stem cell-based modeling of tau pathology in human neurons. The American journal of pathology\| PubMed ID: 23499461	2013
MicroRNA-based promotion of human neuronal differentiation and subtype specification. PloS one\| PubMed ID: 23527072	2013
Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies. Nature reviews. Molecular cell biology\| PubMed ID: 23847783	2013
Anticancer effects of niclosamide in human glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23908450	2013
Auto-attraction of neural precursors and their neuronal progeny impairs neuronal migration. Nature neuroscience\| PubMed ID: 24241396	2014
APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation. Stem cell reports\| PubMed ID: 24371804	2013
Human induced pluripotent stem cells improve recovery in stroke-injured aged rats. Restorative neurology and neuroscience\| PubMed ID: 24916776	2014
Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 26061647	2015
Direct Conversion Provides Old Neurons from Aged Donor's Skin. Cell stem cell\| PubMed ID: 26637936	2015
Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity. Acta neuropathologica\| PubMed ID: 26898910	2016
Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. Cell reports\| PubMed ID: 26923602	2016
Specific Triazine Herbicides Induce Amyloid-β42 Production. Journal of Alzheimer's disease : JAD\| PubMed ID: 27589520	2016
MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility. Translational oncology\| PubMed ID: 27988423	2017
Whole-brain 3D mapping of human neural transplant innervation. Nature communications\| PubMed ID: 28102196	2017
An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome. Cell reports\| PubMed ID: 28380362	2017
The Alzheimer's Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides. Cell reports\| PubMed ID: 28591569	2017
A Little Bit of Guidance: Mini Brains on Their Route to Adolescence. Cell stem cell\| PubMed ID: 28777940	2017
In vitro segregation and isolation of human pluripotent stem cell-derived neural crest cells. Methods (San Diego, Calif.)\| PubMed ID: 29037816	2017