Punam Malik

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center

Affiliated withCincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 13	2018

Other Publications

Article	Year
Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors. Blood\| PubMed ID: 18388180	2008
Placenta growth factor augments endothelin-1 and endothelin-B receptor expression via hypoxia-inducible factor-1 alpha. Blood\| PubMed ID: 18411415	2008
Placenta growth factor induces 5-lipoxygenase-activating protein to increase leukotriene formation in sickle cell disease. Blood\| PubMed ID: 18945963	2009
Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential. Cell stem cell\| PubMed ID: 19041782	2008
Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19384292	2009
A novel human gamma-globin gene vector for genetic correction of sickle cell anemia in a humanized sickle mouse model: critical determinants for successful correction. Blood\| PubMed ID: 19474450	2009
Genotoxic potential of lineage-specific lentivirus vectors carrying the beta-globin locus control region. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 19707188	2009
The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity. PloS one\| PubMed ID: 19746166	2009
Reprogramming erythroid cells for lysosomal enzyme production leads to visceral and CNS cross-correction in mice with Hurler syndrome. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19903883	2009
High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension. Blood\| PubMed ID: 20335221	2010
Placenta growth factor (PlGF), a novel inducer of plasminogen activator inhibitor-1 (PAI-1) in sickle cell disease (SCD). The Journal of biological chemistry\| PubMed ID: 20351105	2010
Genetic correction of sickle cell anemia and beta-thalassemia: progress and new perspective. TheScientificWorldJournal\| PubMed ID: 20419277	2010
Therapy for beta-globinopathies: a brief review and determinants for successful and safe correction. Annals of the New York Academy of Sciences\| PubMed ID: 20712770	2010
Involvement of miR-30c and miR-301a in immediate induction of plasminogen activator inhibitor-1 by placental growth factor in human pulmonary endothelial cells. The Biochemical journal\| PubMed ID: 21175428	2011
Genetic therapy for beta-thalassemia: from the bench to the bedside. Hematology. American Society of Hematology. Education Program\| PubMed ID: 21239833	2010
Biomarkers for early detection of sickle nephropathy. American journal of hematology\| PubMed ID: 21630304	2011
Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management. TheScientificWorldJournal\| PubMed ID: 22924029	2012
Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency. PloS one\| PubMed ID: 23028826	2012
G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment. Genes & development\| PubMed ID: 23105005	2012
Use of induced pluripotent stem cells to recapitulate pulmonary alveolar proteinosis pathogenesis. American journal of respiratory and critical care medicine\| PubMed ID: 24279752	2014
Gene therapy for hemoglobinopathies: the state of the field and the future. Hematology/oncology clinics of North America\| PubMed ID: 24589262	2014
Pulmonary macrophage transplantation therapy. Nature\| PubMed ID: 25274301	2014
Peroxisome proliferator-activated receptor-α-mediated transcription of miR-199a2 attenuates endothelin-1 expression via hypoxia-inducible factor-1α. The Journal of biological chemistry\| PubMed ID: 25389292	2014
MicroRNA 648 Targets ET-1 mRNA and is cotranscriptionally regulated with MICAL3 by PAX5. Molecular and cellular biology\| PubMed ID: 25403488	2015
Perforin gene transfer into hematopoietic stem cells improves immune dysregulation in murine models of perforin deficiency. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 25523759	2015
Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT₂R and cytoskeletal dysregulation. Nature communications\| PubMed ID: 25574809	2015
Erythropoietin-mediated expression of placenta growth factor is regulated via activation of hypoxia-inducible factor-1α and post-transcriptionally by miR-214 in sickle cell disease. The Biochemical journal\| PubMed ID: 25876995	2015
Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies. Molecular therapy. Methods & clinical development\| PubMed ID: 26052523	2014
Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice. Blood\| PubMed ID: 26286849	2015
Peroxisome proliferator-activated receptor-α-mediated transcription of miR-301a and miR-454 and their host gene SKA2 regulates endothelin-1 and PAI-1 expression in sickle cell disease. Bioscience reports\| PubMed ID: 26460070	2015
Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13. The Journal of clinical investigation\| PubMed ID: 26690703	2016
Cardiomyopathy With Restrictive Physiology in Sickle Cell Disease. JACC. Cardiovascular imaging\| PubMed ID: 26897687	2016
Gene Therapy for Hemoglobinopathies: Tremendous Successes and Remaining Caveats. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 27081721	2016
High Level of Perforin Expression Is Required for Effective Correction of Hemophagocytic Lymphohistiocytosis. Human gene therapy\| PubMed ID: 27471778	2016
Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27503873	2016
Activated Transcription Factor 3 in Association with Histone Deacetylase 6 Negatively Regulates MicroRNA 199a2 Transcription by Chromatin Remodeling and Reduces Endothelin-1 Expression. Molecular and cellular biology\| PubMed ID: 27573019	2016
CRISPR/Cas9 in allergic and immunologic diseases. Expert review of clinical immunology\| PubMed ID: 27687572	2017
The potential of gene therapy approaches for the treatment of hemoglobinopathies: achievements and challenges. Therapeutic advances in hematology\| PubMed ID: 27695619	2016
Production and purification of high-titer foamy virus vector for the treatment of leukocyte adhesion deficiency. Molecular therapy. Methods & clinical development\| PubMed ID: 27722179	2016
Gene therapy for hemoglobin disorders - a mini-review. Journal of rare diseases research & treatment\| PubMed ID: 27891535	2016
Purification of baculovirus vectors using heparin affinity chromatography. Molecular therapy. Methods & clinical development\| PubMed ID: 27933303	2016
KIT blockade is sufficient for donor hematopoietic stem cell engraftment in Fanconi anemia mice. Blood\| PubMed ID: 27998889	2017
A reappraisal of the mechanisms underlying the cardiac complications of sickle cell anemia. Pediatric blood & cancer\| PubMed ID: 28453224	2017
Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia. Blood\| PubMed ID: 28507082	2017
Losartan for the nephropathy of sickle cell anemia: A phase-2, multicenter trial. American journal of hematology\| PubMed ID: 28589652	2017
Patient Perspectives on Gene Transfer Therapy for Sickle Cell Disease. Advances in therapy\| PubMed ID: 28717861	2017
Erratum to: Patient Perspectives on Gene Transfer Therapy for Sickle Cell Disease. Advances in therapy\| PubMed ID: 28770518	2017
Placenta growth factor mediated gene regulation in sickle cell disease. Blood reviews\| PubMed ID: 28823762	2018
Foamy Virus Vector Carries a Strong Insulator in Its Long Terminal Repeat Which Reduces Its Genotoxic Potential. Journal of virology\| PubMed ID: 29046446	2018