a-new-method-for-inducing-a-depression-like-behavior-in-rats

A New Method for Inducing a Depression-Like Behavior in Rats

Contagious depression is a phenomenon that is yet to be fully recognized and this stems from insufficient material on the subject. At the moment, there is ...

Ben-Gurion University of the Negev

Acute appendicitis is one of the most common conditions requiring surgical intervention. Open appendectomy has been a safe and effective operation for acute appendicitis for more than a century. Recently, several authors proposed that the new technique of laparoscopic appendectomy should be the preferred treatment for acute appendicitis. However, unlike laparoscopic cholecystectomy, LA has not yet gained popularity.

Laparoscopic versus open appendectomy: results of a retrospective comparison in an Israeli hospital.

Toxoplasmosis is a zoonotic protozoal disease, caused by an obligatory intracellular parasite of the genus Toxoplasma. The disease is widely distributed affecting more than a billion milliard people, worldwide. Raising sheep and cattle, handling and eating raw meat, interaction with domestic cats and climate conditions play an important role in the distribution of the disease. Both Toxoplasma and Plasmodium belong to the Phylum Apicomplexa, and are, therefore, almost similarly sensitive to anti-malarial drugs. Toxoplasmosis is considered to be viscerotropic in adults and children and neurotropic in fetal and newborn children. An accurate and fast diagnosis of the disease is highly important, particularly in pregnant women, since the results may affect both the mother and her fetus. The present study summarizes the old and new techniques available and their importance in the diagnosis of the disease.

[Toxoplasma and toxoplasmosis].

Six cystic echinococcosis patients underwent surgery for the removal of echinococcal cysts. All were treated with albendazole prior to and following treatment. After surgery, no cysts were detected in five of the six patients examined. Both ELISA and immunoblot analysis have been used to determine specific IgG, IgG4 and IgE activities. Total elimination of IgG and IgG4 was not achieved in any of the patients studied. Prior to the first surgery/treatment, specific IgG, IgG4 and IgE antibodies were demonstrated in all patients, except one who did not show any IgE activity. The first treatment was followed by highly elevated IgE in two patients; in one of them it was further combined with an apparent decrease in IgG activity. Repeated treatment with albendazole given 0.8-8.5 years after the first treatment/surgery was followed by either moderate or highly reduced IgE activity in two patients, respectively, and a slight increase in IgG4 in another patient. A third course of treatment, given 2-2.5 years after the second treatment, barely affected the antibody activities. The present study suggests that anti-echinoccocal antibody activity may remain high many years after successful cyst removal. Determination of IgG, IgG4 and IgE responses is preferable for the assessment of treatment results. The presence of anti-echinococcal antibodies after surgery with no cyst detection does not necessarily indicate an active echinococcal infection.

Repeated treatment of cystic echinococcosis in patients with a long-term immunological response after successful surgical cyst removal.

A patient developed a huge diaphragmatic hernia following laparoscopic gastric banding. Almost the entire stomach was incarcerated within the left chest. Segmental necrosis of the greater curvature of the stomach necessitated partial gastrectomy. The postoperative course was uneventful. The etiology, diagnosis and treatment of this previously undescribed complication of laparoscopic gastric banding are addressed in relation to the present case.

Iatrogenic diaphragmatic hernia due to laparoscopic gastric banding.

Unrecognized severe pseudomembranous colitis may become life threatening. A typical Clostridium difficile infection is associated with involvement of the colon; however, small bowel disease has also been described. Here, we present a case of a 48-year-old man with Clostridium difficile colitis of an isolated segment in the descending colon treated by a novel catheter intraluminal antibiotic irrigation. The intraluminal antibiotic irrigation was performed through a Foley catheter inserted into the isolated mucus fistula. The patient recovered after three weeks of intraluminal vancomycin (250 mg diluted in 150 ml of normal saline  x Q6) and metronidazole (500 mg  x Q8). Both antibiotics were given into the mucus fistula over 30 min. The patient was discharged from the unit four weeks after admission. This novel technique, in which the antibiotic was administered through an inserted intraluminal Foley urinary catheter, may be an efficient and safe alternative when conventional routes cannot be implemented.

Unusual localization of clostridium difficile infection in an isolated segment of the descending colon in a critical care patient.

Percutaneous bedside tracheostomy (PBT) is a one of the common and safe procedures in intensive care units through the world. In the present paper we published our clinical experience with a performance of PBTs in the regular ward by intensive care physicians' team. We found it safe and similar outcome in comparison to open surgical tracheostomy method in operation room by ENT team. The performance of PBT in the regular ward showed potential economic advantages in saving medical staff and operating room resources.

Bedside Percutaneous Tracheostomy versus Open Surgical Tracheostomy in Non-ICU Patients.

Upper gastrointestinal tract (GIT) surgical procedures are more likely to cause nosocomialthan lower GIT procedures and they thus constitute an independent risk factor for mortality. Because of the severity of postsurgical fungal infections complications, intensivists and surgeons need to be extremely aware of their clinical importance in critically ill postsurgical intensive care unit (ICU) patients. We analyzed the clinical and microbiological data of 149 oncologic patients who were hospitalized in the ICU at Soroka Medical Center between January 2010 and January 2015 after undergoing upper GIT surgery for gastric cancer. Invasive fungal infections related to secondary peritonitis following oncologic upper GIT surgery had a higher mortality rate than patients with nonfungal postoperative infectious complications. The presence of gastroesophageal junction leakage and advanced age were found to be independent risk factors for invasive fungal infection after oncologic upper GIT surgery.

Article	Year
Laparoscopic versus open appendectomy: results of a retrospective comparison in an Israeli hospital. The Israel Medical Association journal : IMAJ\| PubMed ID: 11875999	2002
[Toxoplasma and toxoplasmosis]. Harefuah\| PubMed ID: 12647490	2003
Repeated treatment of cystic echinococcosis in patients with a long-term immunological response after successful surgical cyst removal. Transactions of the Royal Society of Tropical Medicine and Hygiene\| PubMed ID: 16214196	2006
Iatrogenic diaphragmatic hernia due to laparoscopic gastric banding. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery\| PubMed ID: 16925323	2006
Unusual localization of clostridium difficile infection in an isolated segment of the descending colon in a critical care patient. Case reports in surgery\| PubMed ID: 23316409	2012
Bedside Percutaneous Tracheostomy versus Open Surgical Tracheostomy in Non-ICU Patients. Critical care research and practice\| PubMed ID: 24523960	2014
InvasiveInfection after Upper Gastrointestinal Tract Surgery for Gastric Cancer. International journal of surgical oncology\| PubMed ID: 29234525	2017

Jochanan Peiser

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