Vittorio Sartorelli

Laboratory of Muscle Stem Cells and Gene Regulation, National Institutes of Health

Affiliated withNational Institutes of Health National Institutes of Health (NIH)

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 23	2018
Publication title Cited by 7	2022

Other Publications

Article	Year
IL-6 Blockade as a Therapeutic Approach for Duchenne Muscular Dystrophy. EBioMedicine\| PubMed ID: 26137566	2015
Proteasome-mediated degradation of the coactivator p300 impairs cardiac transcription. Molecular and cellular biology\| PubMed ID: 11073966	2000
HERP, a new primary target of Notch regulated by ligand binding. Molecular and cellular biology\| PubMed ID: 11486044	2001
HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling. Molecular and cellular biology\| PubMed ID: 11486045	2001
The link between chromatin structure, protein acetylation and cellular differentiation. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 11532612	2001
Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12032356	2002
Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Molecular cell\| PubMed ID: 12887892	2003
Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin. Developmental cell\| PubMed ID: 15130492	2004
Tax relieves transcriptional repression by promoting histone deacetylase 1 release from the human T-cell leukemia virus type 1 long terminal repeat. Journal of virology\| PubMed ID: 15194748	2004
Molecular and cellular determinants of skeletal muscle atrophy and hypertrophy. Science's STKE : signal transduction knowledge environment\| PubMed ID: 15292521	2004
The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes & development\| PubMed ID: 15520282	2004
Mechanisms underlying the transcriptional regulation of skeletal myogenesis. Current opinion in genetics & development\| PubMed ID: 16055324	2005
Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway. The Journal of biological chemistry\| PubMed ID: 16267055	2006
Follistatin induction by nitric oxide through cyclic GMP: a tightly regulated signaling pathway that controls myoblast fusion. The Journal of cell biology\| PubMed ID: 16401724	2006
The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation. Developmental cell\| PubMed ID: 17011493	2006
The DEAD-box p68/p72 proteins and the noncoding RNA steroid receptor activator SRA: eclectic regulators of disparate biological functions. Cell cycle (Georgetown, Tex.)\| PubMed ID: 17495528	2007
MyoD acetylation influences temporal patterns of skeletal muscle gene expression. The Journal of biological chemistry\| PubMed ID: 17965412	2007
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Developmental cell\| PubMed ID: 18477450	2008
Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues. Cell cycle (Georgetown, Tex.)\| PubMed ID: 19029811	2008
Mir-214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells. Molecular cell\| PubMed ID: 19818710	2009
MicroRNA-214 and polycomb group proteins: a regulatory circuit controlling differentiation and cell fate decisions. Cell cycle (Georgetown, Tex.)\| PubMed ID: 20372071	2010
Dietary restriction: standing up for sirtuins. Science (New York, N.Y.)\| PubMed ID: 20798296	2010
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. Cell stem cell\| PubMed ID: 20887952	2010
Myc-nick: the force behind c-Myc. Science signaling\| PubMed ID: 21156935	2010
Phosphoryl-EZH-ion. Cell stem cell\| PubMed ID: 21362566	2011
Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells. Genes & development\| PubMed ID: 21498568	2011
Sculpting chromatin beyond the double helix: epigenetic control of skeletal myogenesis. Current topics in developmental biology\| PubMed ID: 21621067	2011
Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis\| PubMed ID: 21828058	2011
Polycomb protein Ezh1 promotes RNA polymerase II elongation. Molecular cell\| PubMed ID: 22196887	2012
Who needs microtubules? Myogenic reorganization of MTOC, Golgi complex and ER exit sites persists despite lack of normal microtubule tracks. PloS one\| PubMed ID: 22216166	2011
STATs shape the active enhancer landscape of T cell populations. Cell\| PubMed ID: 23178119	2012
The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis. The EMBO journal\| PubMed ID: 23503590	2013
BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis. Nature\| PubMed ID: 23728300	2013
The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy. Genes & development\| PubMed ID: 23752591	2013
eRNAs promote transcription by establishing chromatin accessibility at defined genomic loci. Molecular cell\| PubMed ID: 23993744	2013
Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation. Cell\| PubMed ID: 24360274	2013
H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation. eLife\| PubMed ID: 24368734	2013
The emerging roles of eRNAs in transcriptional regulatory networks. RNA biology\| PubMed ID: 24525859	2014
An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noise. BMC evolutionary biology\| PubMed ID: 24707827	2014
Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis. Molecular and cellular biology\| PubMed ID: 25071153	2014
The NAD(+)-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells. Cell stem cell\| PubMed ID: 25600643	2015
Super-enhancers delineate disease-associated regulatory nodes in T cells. Nature\| PubMed ID: 25686607	2015
EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion. Scientific reports\| PubMed ID: 26090605	2015
Metabolic Reprogramming of Stem Cell Epigenetics. Cell stem cell\| PubMed ID: 26637942	2015
The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1. Cell reports\| PubMed ID: 26832413	2016
Polycomb Ezh2 controls the fate of GABAergic neurons in the embryonic cerebellum. Development (Cambridge, England)\| PubMed ID: 27068104	2016
Laminopathies disrupt epigenomic developmental programs and cell fate. Science translational medicine\| PubMed ID: 27099177	2016
S6K1ing to ResTOR Adipogenesis with Polycomb. Molecular cell\| PubMed ID: 27153531	2016
Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells. Cell reports\| PubMed ID: 27783950	2016
Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK. EBioMedicine\| PubMed ID: 28396013	2017
The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins. Molecular cell\| PubMed ID: 29033324	2017
ATP Citrate Lyase: A New Player Linking Skeletal Muscle Metabolism and Epigenetics. Trends in endocrinology and metabolism: TEM\| PubMed ID: 29395431	2018
Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions. Development (Cambridge, England)\| PubMed ID: 30890574	2019