M. Lienhard Schmitz

Institute of Biochemistry, Justus-Liebig-University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 31	2018

Other Publications

Article	Year
Controlling NF-kappaB activation in T cells by costimulatory receptors. Cell death and differentiation\| PubMed ID: 16410801	2006
Autoregulatory control of the p53 response by caspase-mediated processing of HIPK2. The EMBO journal\| PubMed ID: 16601678	2006
Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation. The EMBO journal\| PubMed ID: 16917507	2006
Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2. Molecular cell\| PubMed ID: 17018294	2006
HIPK2: a versatile switchboard regulating the transcription machinery and cell death. Cell cycle (Georgetown, Tex.)\| PubMed ID: 17245128	2007
NF-kappaB inhibitors for the treatment of inflammatory diseases and cancer. Current medicinal chemistry\| PubMed ID: 17305539	2007
NIK and Cot cooperate to trigger NF-kappaB p65 phosphorylation. Biochemical and biophysical research communications\| PubMed ID: 18439422	2008
A bacterial small molecule undermining immune response signaling. Chembiochem : a European journal of chemical biology\| PubMed ID: 18823058	2008
Functional architecture of the cell nucleus. Biochimica et biophysica acta\| PubMed ID: 18929934	2008
An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response. Nature cell biology\| PubMed ID: 19043406	2009
Autoregulatory feedback loops terminating the NF-kappaB response. Trends in biochemical sciences\| PubMed ID: 19233657	2009
Activation of T cells: releasing the brakes by proteolytic elimination of Cbl-b. Science signaling\| PubMed ID: 19549983	2009
SUMOylation-dependent localization of IKKepsilon in PML nuclear bodies is essential for protection against DNA-damage-triggered cell death. Molecular cell\| PubMed ID: 20188669	2010
Specification of the NF-kappaB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKK epsilon. Nucleic acids research\| PubMed ID: 20507904	2010
Control of nuclear HIPK2 localization and function by a SUMO interaction motif. Biochimica et biophysica acta\| PubMed ID: 21145359	2011
Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination. Oncogene\| PubMed ID: 21706061	2012
Signal integration, crosstalk mechanisms and networks in the function of inflammatory cytokines. Biochimica et biophysica acta\| PubMed ID: 21787809	2011
A redox-regulated SUMO/acetylation switch of HIPK2 controls the survival threshold to oxidative stress. Molecular cell\| PubMed ID: 22503103	2012
HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop. Journal of molecular cell biology\| PubMed ID: 23000554	2013
SIAH-mediated ubiquitination and degradation of acetyl-transferases regulate the p53 response and protein acetylation. Biochimica et biophysica acta\| PubMed ID: 23044042	2012
The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-ÎºB. Nucleic acids research\| PubMed ID: 23087373	2012
Regulation of the tumor suppressor PML by sequential post-translational modifications. Frontiers in oncology\| PubMed ID: 23293771	2012
Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression. PloS one\| PubMed ID: 23300567	2012
Posttranslational modifications regulate HIPK2, a driver of proliferative diseases. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 23616089	2013
Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage. Nucleic acids research\| PubMed ID: 23620283	2013
Hsc70 is a novel interactor of NF-kappaB p65 in living hippocampal neurons. PloS one\| PubMed ID: 23762333	2013
The cytokine-induced conformational switch of nuclear factor κB p65 is mediated by p65 phosphorylation. The Biochemical journal\| PubMed ID: 24175631	2014
Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-κB-dependent gene expression. Molecular cell\| PubMed ID: 24389100	2014
Expression pattern of protease activated receptors in lymphoid cells. Cellular immunology\| PubMed ID: 24637088	2014
The intricate interplay between RNA viruses and NF-κB. Biochimica et biophysica acta\| PubMed ID: 25116307	2014
SUMO modification of TBK1 at the adaptor-binding C-terminal coiled-coil domain contributes to its antiviral activity. Biochimica et biophysica acta\| PubMed ID: 25409927	2015
The Activation of IL-1-Induced Enhancers Depends on TAK1 Kinase Activity and NF-κB p65. Cell reports\| PubMed ID: 25660023	2015
Cyclin-Dependent Kinases as Coregulators of Inflammatory Gene Expression. Trends in pharmacological sciences\| PubMed ID: 26719217	2016
HIPK family kinases bind and regulate the function of the CCR4-NOT complex. Molecular biology of the cell\| PubMed ID: 27122605	2016
SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies. Scientific reports\| PubMed ID: 27211601	2016
K63-Ubiquitylation and TRAF6 Pathways Regulate Mammalian P-Body Formation and mRNA Decapping. Molecular cell\| PubMed ID: 27315556	2016
The Influenza A Virus Genotype Determines the Antiviral Function of NF-κB. Journal of virology\| PubMed ID: 27356900	2016
Testing the Effects of SIAH Ubiquitin E3 Ligases on Lysine Acetyl Transferases. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27761830	2017
The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells. PLoS pathogens\| PubMed ID: 28355270	2017
The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription. Scientific reports\| PubMed ID: 28615693	2017
NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation. Biochimica et biophysica acta\| PubMed ID: 28723419	2017
The Direct and Indirect Roles of NF-κB in Cancer: Lessons from Oncogenic Fusion Proteins and Knock-in Mice. Biomedicines\| PubMed ID: 29562713	2018