Nicholas M. Luscombe

European Bioinformatics Institute, EMBL Heidelberg

Affiliated withEMBL Heidelberg Okinawa Institute of Science and Technology Graduate University Francis Crick Institute

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 203	2011
Publication title Cited by 14	2020

Other Publications

Article	Year
Molecular fossils in the human genome: identification and analysis of the pseudogenes in chromosomes 21 and 22. Genome research\| PubMed ID: 11827946	2002
Structural genomics: a new era for pharmaceutical research. Genome biology\| PubMed ID: 11864367	2002
GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11867748	2002
Comprehensive analysis of amino acid and nucleotide composition in eukaryotic genomes, comparing genes and pseudogenes. Nucleic acids research\| PubMed ID: 12034841	2002
Protein-DNA interactions: amino acid conservation and the effects of mutations on binding specificity. Journal of molecular biology\| PubMed ID: 12126620	2002
The dominance of the population by a selected few: power-law behaviour applies to a wide variety of genomic properties. Genome biology\| PubMed ID: 12186647	2002
Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes & development\| PubMed ID: 12464632	2002
The transcriptional activity of human Chromosome 22. Genes & development\| PubMed ID: 12600945	2003
ExpressYourself: A modular platform for processing and visualizing microarray data. Nucleic acids research\| PubMed ID: 12824348	2003
Genomic analysis of gene expression relationships in transcriptional regulatory networks. Trends in genetics : TIG\| PubMed ID: 12902159	2003
Distribution of NF-kappaB-binding sites across human chromosome 22. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14527995	2003
Prediction of regulatory networks: genome-wide identification of transcription factor targets from gene expression data. Bioinformatics (Oxford, England)\| PubMed ID: 14555624	2003
CREB binds to multiple loci on human chromosome 22. Molecular and cellular biology\| PubMed ID: 15082775	2004
Annotation transfer between genomes: protein-protein interologs and protein-DNA regulogs. Genome research\| PubMed ID: 15173116	2004
Structure and evolution of transcriptional regulatory networks. Current opinion in structural biology\| PubMed ID: 15193307	2004
Genomic analysis of regulatory network dynamics reveals large topological changes. Nature\| PubMed ID: 15372033	2004
GenCompass: a universal system for analysing gene expression for any genome. Trends in biotechnology\| PubMed ID: 15491796	2004
Transcriptional networking. Genome biology\| PubMed ID: 16168097	2005
Comprehensive analysis of combinatorial regulation using the transcriptional regulatory network of yeast. Journal of molecular biology\| PubMed ID: 16762362	2006
Extrapolating traditional DNA microarray statistics to tiling and protein microarray technologies. Methods in enzymology\| PubMed ID: 16939796	2006
Transcriptional regulatory networks in bacteria: from input signals to output responses. Current opinion in microbiology\| PubMed ID: 16942903	2006
Transcriptomics and adaptive genomics of the asymptomatic bacteriuria Escherichia coli strain 83972. Molecular genetics and genomics : MGG\| PubMed ID: 18317809	2008
Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility. Journal of bacteriology\| PubMed ID: 18375554	2008
Genome-wide analysis reveals MOF as a key regulator of dosage compensation and gene expression in Drosophila. Cell\| PubMed ID: 18510926	2008
Principles of transcriptional regulation and evolution of the metabolic system in E. coli. Genome research\| PubMed ID: 18836036	2009
A census of human transcription factors: function, expression and evolution. Nature reviews. Genetics\| PubMed ID: 19274049	2009
Know your limits: assumptions, constraints and interpretation in systems biology. Biochimica et biophysica acta\| PubMed ID: 19439202	2009
Nuclear pore proteins nup153 and megator define transcriptionally active regions in the Drosophila genome. PLoS genetics\| PubMed ID: 20174442	2010
多路复用大规模并行技术表征人类转录因子具有约束&#x529... Genome research\| PubMed ID: 20378718	2010
Comprehensive reanalysis of transcription factor knockout expression data in Saccharomyces cerevisiae reveals many new targets. Nucleic acids research\| PubMed ID: 20385592	2010
Comparative genomics of cyclic-di-GMP signalling in bacteria: post-translational regulation and catalytic activity. Nucleic acids research\| PubMed ID: 20483912	2010
iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution. Nature structural & molecular biology\| PubMed ID: 20601959	2010
The nonspecific lethal complex is a transcriptional regulator in Drosophila. Molecular cell\| PubMed ID: 20620954	2010
iCLIP predicts the dual splicing effects of TIA-RNA interactions. PLoS biology\| PubMed ID: 21048981	2010
Direct and indirect effects of H-NS and Fis on global gene expression control in Escherichia coli. Nucleic acids research\| PubMed ID: 21097887	2011
Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice. EMBO molecular medicine\| PubMed ID: 21204268	2011
An overview of prokaryotic transcription factors : a summary of function and occurrence in bacterial genomes. Sub-cellular biochemistry\| PubMed ID: 21557077	2011
Large-scale nuclear architecture and transcriptional control. Sub-cellular biochemistry\| PubMed ID: 21557088	2011
The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1. Molecular & cellular proteomics : MCP\| PubMed ID: 21808052	2011
Comparative genomics suggests differential deployment of linear and branched signaling across bacteria. Molecular bioSystems\| PubMed ID: 21879110	2011
A genomic model of condition-specific nucleosome behavior explains transcriptional activity in yeast. Genome research\| PubMed ID: 21930892	2012
How do you find transcription factors? Computational approaches to compile and annotate repertoires of regulators for any genome. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21938617	2012
SpeCond: a method to detect condition-specific gene expression. Genome biology\| PubMed ID: 22008066	2011
Genomic analysis of DNA binding and gene regulation by homologous nucleoid-associated proteins IHF and HU in Escherichia coli K12. Nucleic acids research\| PubMed ID: 22180530	2011
SpeCond: a method to detect condition-specific gene expression. Genome biology\| PubMed ID: 22212554	2011
Protein-RNA interactions: new genomic technologies and perspectives. Nature reviews. Genetics\| PubMed ID: 22251872	2011