invasive-hemodynamic-monitoring-aortic-pulmonary-artery-hemodynamics

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS

One of the leading causes of morbidity and mortality in patients with heart failure is right ventricular (RV) dysfunction, especially if it is due to ...

real-time-assessment-spinal-cord-microperfusion-porcine-model

Real-Time Assessment of Spinal Cord Microperfusion in a Porcine Model of Ischemia/Reperfusion

Spinal cord injury is a devastating complication of aortic repair. Despite developments for the prevention and treatment of spinal cord injury, its ...

Universitatsklinikum Hamburg-Eppendorf

University Medical Center Hamburg-Eppendorf

Severe acute pancreatitis (SAP) remains a life-threatening disease with classic etiology of systemic inflammatory response and mortality between 30 and 50 %. The aim of the present study is to compare two different treatment strategies of goal-directed hemodynamic management and evaluate their impact on survival, microcirculation, tissue oxygenation, and histopathologic damage in acute pancreatitis in a prospective animal study.

The impact of early goal-directed fluid management on survival in an experimental model of severe acute pancreatitis.

Cerebrospinal fluid (CSF) drainage is routinely utilized to mitigate perioperative and postoperative spinal cord ischaemia in open and endovascular thoraco-abdominal aortic aneurysm repair to prevent permanent paraplegia. Clinical decision-making in the vulnerable perioperative period, however, is still based on limited clinical and experimental data. Our aim was to investigate the isolated effect of CSF pressure elevation on spinal cord perfusion in an established large animal model.

ArticleTotal : 2	Year
Publication title Cited by 5	2018
Publication title Cited by 5	2020

Article	Year
The impact of early goal-directed fluid management on survival in an experimental model of severe acute pancreatitis. Intensive care medicine\| PubMed ID: 23287870	2013
Detrimental effects of cerebrospinal fluid pressure elevation on spinal cord perfusion: first-time direct detection in a large animal model. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 32236546	2020

Till Friedheim

Biography

JoVE Journal Publications

Other Publications