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Real-Time Assessment of Spinal Cord Microperfusion in a Porcine Model of Ischemia/Reperfusion
JoVE Journal
Medicine
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JoVE Journal Medicine
Real-Time Assessment of Spinal Cord Microperfusion in a Porcine Model of Ischemia/Reperfusion
DOI:

10:27 min

December 10, 2020

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Chapters

  • 00:04Introduction
  • 01:02Probe Placement
  • 04:22Surgical Preparation
  • 05:52Hemodynamic Parameter Measurement
  • 08:04Results: Representative Hemodynamic Changes During Ischemia and Reperfusion
  • 09:50Conclusion

Summary

Automatic Translation

Spinal cord microcirculation plays a pivotal role in spinal cord injury. Most methods do not allow real-time assessment of spinal cord microcirculation, which is essential for the development of microcirculation-targeted therapies. Here, we propose a protocol using Laser-Doppler-Flow Needle probes in a large animal model of ischemia/reperfusion.

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