Rudolf Jaenisch

Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology

Affiliated withWhitehead Institute for Biomedical Research, Massachusetts Institute of Technology Whitehead Institute for Biomedical Research Massachusetts Institute of Technology

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 41	2008
Publication title Cited by 10	2010

Other Publications

Article	Year
Chromosomal silencing and localization are mediated by different domains of Xist RNA. Nature genetics\| PubMed ID: 11780141	2002
Neurotrophin-3 promotes cell death induced in cerebral ischemia, oxygen-glucose deprivation, and oxidative stress: possible involvement of oxygen free radicals. Neurobiology of disease\| PubMed ID: 11848682	2002
Flp recombinase regulated lacZ expression at the ROSA26 locus. Genesis (New York, N.Y. : 2000)\| PubMed ID: 11857816	2002
Monoclonal mice generated by nuclear transfer from mature B and T donor cells. Nature\| PubMed ID: 11875572	2002
Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. Molecular and cellular biology\| PubMed ID: 11884600	2002
Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy. Cell\| PubMed ID: 11955443	2002
Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nature biotechnology\| PubMed ID: 11981557	2002
Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12019333	2002
Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12235366	2002
Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist. Journal of cell science\| PubMed ID: 12356914	2002
Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12432090	2002
X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse. Genesis (New York, N.Y. : 2000)\| PubMed ID: 12434336	2002
Nuclear transplantation: lessons from frogs and mice. Current opinion in cell biology\| PubMed ID: 12473349	2002
Stroke damage in mice after knocking the neutrophin-4 gene into the brain-derived neurotrophic factor locus. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 12571446	2003
Rapid generation of inducible mouse mutants. Nucleic acids research\| PubMed ID: 12582257	2003
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nature genetics\| PubMed ID: 12610534	2003
Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development (Cambridge, England)\| PubMed ID: 12620990	2003
HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell\| PubMed ID: 12628185	2003
Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization. Genes & development\| PubMed ID: 12651894	2003
Chromosomal instability and tumors promoted by DNA hypomethylation. Science (New York, N.Y.)\| PubMed ID: 12702868	2003
Induction of tumors in mice by genomic hypomethylation. Science (New York, N.Y.)\| PubMed ID: 12702876	2003
Stem cells. Setting standards for human embryonic stem cells. Science (New York, N.Y.)\| PubMed ID: 12738841	2003
Hybrid embryonic stem cell-derived tetraploid mice show apparently normal morphological, physiological, and neurological characteristics. Molecular and cellular biology\| PubMed ID: 12748299	2003
Nuclear transplantation, embryonic stem cells, and the potential for cell therapy. The New England journal of medicine\| PubMed ID: 12867612	2003
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science (New York, N.Y.)\| PubMed ID: 14593183	2003
Differentiation of F1 embryonic stem cells into viable male and female mice by tetraploid embryo complementation. Methods in enzymology\| PubMed ID: 14696335	2003
Mice cloned from olfactory sensory neurons. Nature\| PubMed ID: 14990966	2004
Micromanipulating dosage compensation: understanding X-chromosome inactivation through nuclear transplantation. Seminars in cell & developmental biology\| PubMed ID: 15015742	2003
Wt1 functions in the development of germ cells in addition to somatic cell lineages of the testis. Developmental biology\| PubMed ID: 15063178	2004
Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15069197	2004
Nuclear transplantation, embryonic stem cells and the potential for cell therapy. The hematology journal : the official journal of the European Haematology Association / EHA\| PubMed ID: 15190291	2004
Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. The Journal of clinical investigation\| PubMed ID: 15199406	2004
Cre-lox-regulated conditional RNA interference from transgenes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15240889	2004
Reprogramming of a melanoma genome by nuclear transplantation. Genes & development\| PubMed ID: 15289459	2004
Nuclear cloning of embryonal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15306687	2004
Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch. Science (New York, N.Y.)\| PubMed ID: 15326357	2004
At most three ES cells contribute to the somatic lineages of chimeric mice and of mice produced by ES-tetraploid complementation. Developmental biology\| PubMed ID: 15464582	2004
Sixteenth Annual Pezcoller Symposium: stem cells and epigenesis in cancer. Cancer research\| PubMed ID: 15548721	2004
Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome. The Journal of cell biology\| PubMed ID: 15596546	2004
Human cloning - the science and ethics of nuclear transplantation. The New England journal of medicine\| PubMed ID: 15625328	2004
X chromosome choice occurs independently of asynchronous replication timing. The Journal of cell biology\| PubMed ID: 15668296	2005
Direct in vivo VH to JH rearrangement violating the 12/23 rule. The Journal of experimental medicine\| PubMed ID: 15699070	2005
DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A. Journal of cell science\| PubMed ID: 15784683	2005
Normal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factor. Visual neuroscience\| PubMed ID: 15842738	2005
Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell\| PubMed ID: 15882627	2005
Characterization of a highly variable eutherian microRNA gene. RNA (New York, N.Y.)\| PubMed ID: 15987809	2005
Nuclear cloning, embryonic stem cells, and transplantation therapy. Harvey lectures\| PubMed ID: 16033160	2002
Nuclear cloning, epigenetic reprogramming and cellular differentiation. Novartis Foundation symposium\| PubMed ID: 16050253	2005
Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16116096	2005
Core transcriptional regulatory circuitry in human embryonic stem cells. Cell\| PubMed ID: 16153702	2005
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16174748	2005
Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice. Biological psychiatry\| PubMed ID: 16199017	2006
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic acids research\| PubMed ID: 16224102	2005
Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer cell\| PubMed ID: 16226703	2005
Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts. Nature\| PubMed ID: 16227971	2006
Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis (New York, N.Y. : 2000)\| PubMed ID: 16400644	2006
Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice. Journal of neurobiology\| PubMed ID: 16408297	2006
ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16418286	2006
The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. Neuron\| PubMed ID: 16446138	2006
Politically correct human embryonic stem cells? The New England journal of medicine\| PubMed ID: 16540629	2006
Suppression of intestinal neoplasia by deletion of Dnmt3b. Molecular and cellular biology\| PubMed ID: 16581773	2006
Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature\| PubMed ID: 16625203	2006
Control of developmental regulators by Polycomb in human embryonic stem cells. Cell\| PubMed ID: 16630818	2006
A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell\| PubMed ID: 16630819	2006
NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis. Learning & memory (Cold Spring Harbor, N.Y.)\| PubMed ID: 16705139	2006
Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus. Stem cells (Dayton, Ohio)\| PubMed ID: 16709876	2006
Nuclear reprogramming and pluripotency. Nature\| PubMed ID: 16810240	2006
Mammalian nuclear transfer. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 16881069	2006
Molecular control of pluripotency. Current opinion in genetics & development\| PubMed ID: 16920351	2006
Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Molecular and cellular biology\| PubMed ID: 16980619	2006
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nature genetics\| PubMed ID: 17259983	2007
On the cloning of animals from terminally differentiated cells. Nature genetics\| PubMed ID: 17262020	2007
Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17267601	2007
Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways. Blood\| PubMed ID: 17317860	2007
Commentary: isolated stem cells--patentable as cultural artifacts? Stem cells (Dayton, Ohio)\| PubMed ID: 17347494	2007
Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis. Genes & development\| PubMed ID: 17369402	2007
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 17477386	2007
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature\| PubMed ID: 17554336	2007
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature\| PubMed ID: 17603471	2007
Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17617584	2007
A chromatin landmark and transcription initiation at most promoters in human cells. Cell\| PubMed ID: 17632057	2007
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nature biotechnology\| PubMed ID: 17724450	2007
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PloS one\| PubMed ID: 17878930	2007
YAP1 increases organ size and expands undifferentiated progenitor cells. Current biology : CB\| PubMed ID: 17980593	2007
Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes & development\| PubMed ID: 18056424	2007
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science (New York, N.Y.)\| PubMed ID: 18063756	2007
Oct4 expression is not required for mouse somatic stem cell self-renewal. Cell stem cell\| PubMed ID: 18159219	2007
The pluripotency regulator Oct4: a role in somatic stem cells? Cell cycle (Georgetown, Tex.)\| PubMed ID: 18239456	2008
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell\| PubMed ID: 18295576	2008
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell\| PubMed ID: 18329372	2008
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell stem cell\| PubMed ID: 18371336	2007
Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell stem cell\| PubMed ID: 18371368	2007
New advances in iPS cell research do not obviate the need for human embryonic stem cells. Cell stem cell\| PubMed ID: 18371375	2007
c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell stem cell\| PubMed ID: 18371415	2008
Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell stem cell\| PubMed ID: 18371436	2008
Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell stem cell\| PubMed ID: 18371437	2008
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18391196	2008
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell\| PubMed ID: 18423197	2008
Dissecting direct reprogramming through integrative genomic analysis. Nature\| PubMed ID: 18509334	2008
Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes & development\| PubMed ID: 18559477	2008
Somatic cell nuclear transfer and derivation of embryonic stem cells in the mouse. Methods (San Diego, Calif.)\| PubMed ID: 18593608	2008
A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nature biotechnology\| PubMed ID: 18594521	2008
Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature\| PubMed ID: 18600261	2008
Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18614692	2008
Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression. Stem cells (Dayton, Ohio)\| PubMed ID: 18635867	2008
Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell stem cell\| PubMed ID: 18682236	2008
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell\| PubMed ID: 18692474	2008
Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET. Genome biology\| PubMed ID: 18700969	2008
Interview with Rudolf Jaenisch, M.D. Rejuvenation research\| PubMed ID: 18729819	2008
Nanoparticles for gene transfer to human embryonic stem cell colonies. Nano letters\| PubMed ID: 18754690	2008
A drug-inducible system for direct reprogramming of human somatic cells to pluripotency. Cell stem cell\| PubMed ID: 18786421	2008
Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations. Gastroenterology\| PubMed ID: 18992744	2009
H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment. Cell\| PubMed ID: 18992931	2008
Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells. Nature biotechnology\| PubMed ID: 19060879	2009
Derivation and manipulation of murine embryonic stem cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19089346	2009
Reprogramming of murine and human somatic cells using a single polycistronic vector. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19109433	2009
Celebrating 10 years of hESC lines: an interview with Rudolf Jaenisch. Stem cells (Dayton, Ohio)\| PubMed ID: 19112652	2008
Microfluidic control of cell pairing and fusion. Nature methods\| PubMed ID: 19122668	2009
Transgenic mice with defined combinations of drug-inducible reprogramming factors. Nature biotechnology\| PubMed ID: 19151700	2009
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature\| PubMed ID: 19182780	2009
Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19208815	2009
Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19225110	2009
Broader implications of defining standards for the pluripotency of iPSCs. Cell stem cell\| PubMed ID: 19265657	2009
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell\| PubMed ID: 19269371	2009
Epigenetic hierarchy governing Nestin expression. Stem cells (Dayton, Ohio)\| PubMed ID: 19415779	2009
HDAC2 negatively regulates memory formation and synaptic plasticity. Nature\| PubMed ID: 19424149	2009
Metastable pluripotent states in NOD-mouse-derived ESCs. Cell stem cell\| PubMed ID: 19427283	2009
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19447925	2009
DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19470733	2009
Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 19590195	2009
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circulation research\| PubMed ID: 19679836	2009
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nature biotechnology\| PubMed ID: 19680244	2009
Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 19703934	2009
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nature genetics\| PubMed ID: 19801979	2009
Direct cell reprogramming is a stochastic process amenable to acceleration. Nature\| PubMed ID: 19898493	2009
Technical challenges in using human induced pluripotent stem cells to model disease. Cell stem cell\| PubMed ID: 19951687	2009
Single-gene transgenic mouse strains for reprogramming adult somatic cells. Nature methods\| PubMed ID: 20010831	2010
TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20042591	2010
Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 20145206	2010
Generation of iPSCs from cultured human malignant cells. Blood\| PubMed ID: 20233975	2010
Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT. Science (New York, N.Y.)\| PubMed ID: 20378817	2010
Two-step imprinted X inactivation: repeat versus genic silencing in the mouse. Molecular and cellular biology\| PubMed ID: 20404085	2010
Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells. 1990. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20410495	2010
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20442331	2010
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell\| PubMed ID: 20471072	2010
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. Genome research\| PubMed ID: 20508142	2010
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nature medicine\| PubMed ID: 20616797	2010
Reprogramming of human peripheral blood cells to induced pluripotent stem cells. Cell stem cell\| PubMed ID: 20621045	2010
Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. Cell stem cell\| PubMed ID: 20682450	2010
Position-dependent silencing of germline VÃŸ segments on TCRÃŸ alleles containing preassembled VÃŸDJÃŸCÃŸ1 genes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20709953	2010
Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells. Nature materials\| PubMed ID: 20729850	2010
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20798034	2010
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20956329	2010
Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell\| PubMed ID: 21074044	2010
Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21106759	2010
Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer. The Journal of clinical investigation\| PubMed ID: 21490393	2011
Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells. Angewandte Chemie (International ed. in English)\| PubMed ID: 21547985	2011
Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors. Stem cells (Dayton, Ohio)\| PubMed ID: 21563275	2011
A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells. PLoS genetics\| PubMed ID: 21573140	2011
De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. Genes & development\| PubMed ID: 21576263	2011
Genetic engineering of human pluripotent cells using TALE nucleases. Nature biotechnology\| PubMed ID: 21738127	2011
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell\| PubMed ID: 21757228	2011
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell stem cell\| PubMed ID: 21816367	2011
Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21844366	2011
Transgene excision has no impact on in vivo integration of human iPS derived neural precursors. PloS one\| PubMed ID: 21961042	2011
Blimp1 expression predicts embryonic stem cell development inÂ vitro. Current biology : CB\| PubMed ID: 22000107	2011
Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22011581	2011
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell stem cell\| PubMed ID: 22019014	2011
Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22065768	2011
Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells. Cell stem cell\| PubMed ID: 22136932	2011