Masahide Takahashi

Masahide Takahashi

Department of Pathology, Nagoya University Graduate School of Medicine

Affiliated withNagoya University Graduate School of MedicineFujita Health University

Research Area

Biography

I graduated from Nagoya University School of Medicine in 1979. I majored in Pathology at Nagoya University Graduate School of Medicine and received PhD degree in 1983. Then I studied as a research fellow at Dana-Farber Cancer Institute and Harvard Medical School in Boston between 1983 and 1985. After returning to Japan, I worked as a researcher at Aichi Cancer Center Research Institute in Nagoya between 1985 and 1990, and moved to Nagoya University as Assistant Professor. I became Professor of Pathology at Nagoya University in 1996. I was appointed to be Dean of Nagoya University School of Medicine between 2012 and 2017, and Trustee and Vice President of Nagoya University between 2017 and 2020. I became Director and Professor of International Center for Cell and Gene Therapy at Fujita Health University in 2020.

JoVE Journal Publications

ArticleTotal : 2
Year
Use of Anti-phospho-girdin Antibodies to Visualize Intestinal Tuft Cells in Free-Floating Mouse Jejunum Cryosections
Publication title

Cited by 3

2018
2021

Other Publications

Article
Year
The GDNF/RET signaling pathway and human diseases.

Cytokine & growth factor reviews| PubMed ID: 11544105

2001
Role for O-glycosylation of RFP in the interaction with enhancer of polycomb.

Biochemical and biophysical research communications| PubMed ID: 11779184

2002
2002
2002
2002
Activation of RET tyrosine kinase regulates interleukin-8 production by multiple signaling pathways.

Biochemical and biophysical research communications| PubMed ID: 12056817

2002
Role of Dok1 in cell signaling mediated by RET tyrosine kinase.

The Journal of biological chemistry| PubMed ID: 12087092

2002
Characterization of gene expression induced by RET with MEN2A or MEN2B mutation.

The American journal of pathology| PubMed ID: 12107109

2002
Overexpression of interleukin-15 prevents the development of murine retrovirus-induced acquired immunodeficiency syndrome.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 12409318

2002
2002
2003
2003
2003
2003
Identification of RET autophosphorylation sites by mass spectrometry.

The Journal of biological chemistry| PubMed ID: 14711813

2004
2004
RET and neuroendocrine tumors.

Cancer letters| PubMed ID: 15013219

2004
Expression of CD109 in human cancer.

Oncogene| PubMed ID: 15116102

2004
Induction of CRMP-2 by GDNF and analysis of the CRMP-2 promoter region.

Biochemical and biophysical research communications| PubMed ID: 15207709

2004
2004
2004
2004
2004
2004
2005
CD109 expression in squamous cell carcinoma of the uterine cervix.

Pathology international| PubMed ID: 15826242

2005
2005
Activation of c-Jun amino-terminal kinase by GDNF induces G2/M cell cycle delay linked with actin reorganization.

Genes to cells : devoted to molecular & cellular mechanisms| PubMed ID: 15966897

2005
2005
2005
2005
2006
Analyses of ultraviolet-induced focus formation of hREV1 protein.

Genes to cells : devoted to molecular & cellular mechanisms| PubMed ID: 16483309

2006
2006
2006
RET and neuroendocrine tumors.

Pituitary| PubMed ID: 17036197

2006
2006
2006
2007
2007
2007
2007
2007
2007
2007
A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1.

Biochemical and biophysical research communications| PubMed ID: 18060868

2008
2008
2008
GDNF-mediated signaling via RET tyrosine 1062 is essential for maintenance of spermatogonial stem cells.

Genes to cells : devoted to molecular & cellular mechanisms| PubMed ID: 18363967

2008
CD109 expression in basal-like breast carcinoma.

Pathology international| PubMed ID: 18429827

2008
2008
2009
2009
2009
2009
2009
2009
2009
2010
2010
c-Ret-mediated hearing loss in mice with Hirschsprung disease.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20616061

2010
2010
2011
2011
2011
2011
Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 21632933

2011
2011
Proteomic analysis of hippocampal proteins of F344 rats exposed to 1-bromopropane.

Toxicology and applied pharmacology| PubMed ID: 21925529

2011
2011
2011
2012
2012
2012
2012
2012
2012
Epidermal hyperplasia and appendage abnormalities in mice lacking CD109.

The American journal of pathology| PubMed ID: 22846721

2012
2012
2013
2012
2013
2013
2014
2014
2015
2013
Silencing of TBC1D15 promotes RhoA activation and membrane blebbing.

Molecular and cellular biochemistry| PubMed ID: 24337944

2014
2014
2014
2014
2011
2014
2014
Girdin phosphorylation is crucial for synaptic plasticity and memory: a potential role in the interaction of BDNF/TrkB/Akt signaling with NMDA receptor.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 25378165

2014
2015
2015
Girdin is phosphorylated on tyrosine 1798 when associated with structures required for migration.

Biochemical and biophysical research communications| PubMed ID: 25707853

2015
CD109 attenuates TGF-β1 signaling and enhances EGF signaling in SK-MG-1 human glioblastoma cells.

Biochemical and biophysical research communications| PubMed ID: 25724945

2015
2015
2015
2015
2015
Rabphilin-3A as a Targeted Autoantigen in Lymphocytic Infundibulo-neurohypophysitis.

The Journal of clinical endocrinology and metabolism| PubMed ID: 25919460

2015
Potential involvement of kinesin-1 in the regulation of subcellular localization of Girdin.

Biochemical and biophysical research communications| PubMed ID: 26072378

2015
2015
2015
2016
Akt-Girdin as oncotarget.

Oncoscience| PubMed ID: 26682257

2015
CD109 is a component of exosome secreted from cultured cells.

Biochemical and biophysical research communications| PubMed ID: 26707640

2016
2016
CCDC88A mutations cause PEHO-like syndrome in humans and mouse.

Brain : a journal of neurology| PubMed ID: 26917597

2016
2016
2016
2016
2016
2017
Tyrosine Phosphorylation of an Actin-Binding Protein Girdin Specifically Marks Tuft Cells in Human and Mouse Gut.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society| PubMed ID: 28375676

2017
2017
2017
2017
2018
2018
2018
2018
2018
CD109 deficiency induces osteopenia with an osteoporosis-like phenotype in vivo.

Genes to cells : devoted to molecular & cellular mechanisms| PubMed ID: 29767469

2018
2018
2018
Chemerin promotes angiogenesis in vivo.

Physiological reports| PubMed ID: 30588761

2018
Cancer-associated fibroblasts in gastrointestinal cancer.

Nature reviews. Gastroenterology & hepatology| PubMed ID: 30778141

2019
Dephosphorylation of Girdin by PP2A inhibits breast cancer metastasis.

Biochemical and biophysical research communications| PubMed ID: 30935690

2019
2019
2019
2019
2020
2020
2020
2020
2021
Intracellular RET signaling pathways activated by GDNF.

Cell and tissue research| PubMed ID: 32816064

2020
2020
The Daple-CK1ε complex regulates Dvl2 phosphorylation and canonical Wnt signaling.

Biochemical and biophysical research communications| PubMed ID: 32888647

2020
2020
2020
2020
2021
2021
2021
Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity.

Genes to cells : devoted to molecular & cellular mechanisms| PubMed ID: 33960573

2021
2021
2021