John C. Schimenti

Department of Biomedical Sciences, Cornell University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2018

Other Publications

Article	Year
The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm. Molecular and cellular biology\| PubMed ID: 15542845	2004
Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations. Genome research\| PubMed ID: 16024820	2005
The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. The EMBO journal\| PubMed ID: 16222339	2005
Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations. Genetics\| PubMed ID: 17151244	2007
A dominant, recombination-defective allele of Dmc1 causing male-specific sterility. PLoS biology\| PubMed ID: 17425408	2007
Different regulatory systems operate in the midpiece and principal piece of the mammalian sperm flagellum. Society of Reproduction and Fertility supplement\| PubMed ID: 17644973	2007
Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis. PLoS genetics\| PubMed ID: 17696610	2007
Mutation in mouse hei10, an e3 ubiquitin ligase, disrupts meiotic crossing over. PLoS genetics\| PubMed ID: 17784788	2007
The dual bromodomain and WD repeat-containing mouse protein BRWD1 is required for normal spermiogenesis and the oocyte-embryo transition. Developmental biology\| PubMed ID: 18353305	2008
Development and use of DNA archives at veterinary teaching hospitals to investigate the genetic basis of disease in dogs. Journal of the American Veterinary Medical Association\| PubMed ID: 19119968	2009
Mouse H6 Homeobox 1 (Hmx1) mutations cause cranial abnormalities and reduced body mass. BMC developmental biology\| PubMed ID: 19379485	2009
Aneuploidy and improved growth are coincident but not causal in a yeast cancer model. PLoS biology\| PubMed ID: 19636358	2009
SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells. BMC developmental biology\| PubMed ID: 20170518	2010
Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality. The Journal of biological chemistry\| PubMed ID: 20197277	2010
An allele separating skeletal patterning and spermatogonial renewal functions of PLZF. BMC developmental biology\| PubMed ID: 20338044	2010
PDCD2 is essential for inner cell mass development and embryonic stem cell maintenance. Developmental biology\| PubMed ID: 20813103	2010
The full-length isoform of the mouse pleckstrin homology domain-interacting protein (PHIP) is required for postnatal growth. FEBS letters\| PubMed ID: 20816727	2010
Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress. PLoS genetics\| PubMed ID: 20838603	2010
High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5. BMC genetics\| PubMed ID: 21118569	2010
A reduction of licensed origins reveals strain-specific replication dynamics in mice. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 21611832	2011
A-MYB (MYBL1) transcription factor is a master regulator of male meiosis. Development (Cambridge, England)\| PubMed ID: 21750041	2011
Genetic evidence that synaptonemal complex axial elements govern recombination pathway choice in mice. Genetics\| PubMed ID: 21750255	2011
Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase. Genes\| PubMed ID: 21779533	2010
Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21987787	2011
Spata22, a novel vertebrate-specific gene, is required for meiotic progress in mouse germ cells. Biology of reproduction\| PubMed ID: 22011390	2012
Haploid embryonic stem cells and the dominance of recessive traits. Cell stem cell\| PubMed ID: 22136917	2011
Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis. PLoS genetics\| PubMed ID: 22346761	2012
MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans. The Journal of clinical investigation\| PubMed ID: 22354170	2012
Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells. Nucleic acids research\| PubMed ID: 22362746	2012
MARF1 regulates essential oogenic processes in mice. Science (New York, N.Y.)\| PubMed ID: 22442484	2012
Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver. Genetics\| PubMed ID: 22851646	2012
Genetic background affects induced pluripotent stem cell generation. Stem cell research & therapy\| PubMed ID: 22862934	2012
Genetics of meiosis and recombination in mice. International review of cell and molecular biology\| PubMed ID: 22878107	2012
Using genetic networks and homology to understand the evolution of phenotypic traits. Current genomics\| PubMed ID: 22942677	2012
Tissue-specific functional networks for prioritizing phenotype and disease genes. PLoS computational biology\| PubMed ID: 23028291	2012
Meiosis arrest female 1 (MARF1) has nuage-like function in mammalian oocytes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23090997	2012
Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. PLoS genetics\| PubMed ID: 23133405	2012
The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination. Molecular and cellular biology\| PubMed ID: 23401855	2013
An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes. Molecular cell\| PubMed ID: 23523368	2013
AKAP9 is essential for spermatogenesis and sertoli cell maturation in mice. Genetics\| PubMed ID: 23608191	2013
Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress. Oncogene\| PubMed ID: 23975433	2014
Female mice lacking estrogen receptor-alpha in osteoblasts have compromised bone mass and strength. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 24038209	2014
IQ motif-containing G (Iqcg) is required for mouse spermiogenesis. G3 (Bethesda, Md.)\| PubMed ID: 24362311	2014
Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway. Science (New York, N.Y.)\| PubMed ID: 24482479	2014
STAG3 is a strong candidate gene for male infertility. Human molecular genetics\| PubMed ID: 24608227	2014
miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment. Cell reports\| PubMed ID: 24630988	2014
Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow-derived stromal cells in vitro. Regenerative medicine\| PubMed ID: 24773530	2014
Applying "gold standards" to in-vitro-derived germ cells. Cell\| PubMed ID: 24906145	2014
Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signaling. PLoS genetics\| PubMed ID: 25010009	2014
A method for isolating high quality RNA from mouse cortical and cancellous bone. Bone\| PubMed ID: 25073031	2014
A mouse geneticist's practical guide to CRISPR applications. Genetics\| PubMed ID: 25271304	2015
Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability. The Journal of cell biology\| PubMed ID: 25547156	2015
Effects of Deletion of ERα in Osteoblast-Lineage Cells on Bone Mass and Adaptation to Mechanical Loading Differ in Female and Male Mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 25707500	2015
Mechanism and regulation of rapid telomere prophase movements in mouse meiotic chromosomes. Cell reports\| PubMed ID: 25892231	2015
The genetics of human infertility by functional interrogation of SNPs in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26240362	2015
MCM9 deficiency delays primordial germ cell proliferation independent of the ATM pathway. Genesis (New York, N.Y. : 2000)\| PubMed ID: 26388201	2015
Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation. PLoS genetics\| PubMed ID: 26765334	2016
Transcriptional profiling of cortical versus cancellous bone from mechanically-loaded murine tibiae reveals differential gene expression. Bone\| PubMed ID: 26876048	2016
L. C. Dunn and Donald Charles on Quantitative Traits in the Mouse. Genetics\| PubMed ID: 26953264	2016
The Chromatin Remodeling Component Arid1a Is a Suppressor of Spontaneous Mammary Tumors in Mice. Genetics\| PubMed ID: 27280691	2016
Repair of Meiotic DNA Breaks and Homolog Pairing in Mouse Meiosis Requires a Minichromosome Maintenance (MCM) Paralog. Genetics\| PubMed ID: 27986806	2017
Pharmacological Inhibition of the DNA Damage Checkpoint Prevents Radiation-Induced Oocyte Death. Genetics\| PubMed ID: 28576861	2017
The DNA Damage Checkpoint Eliminates Mouse Oocytes with Chromosome Synapsis Failure. Molecular cell\| PubMed ID: 28844861	2017