Lee M. Nadler

Medical Oncology, Dana Farber Cancer Institute

Affiliated withDana Farber Cancer Institute Brigham and Womens Hospital

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2011

Other Publications

Article	Year
A phase III study of anti-B4-blocked ricin as adjuvant therapy post-autologous bone marrow transplant: CALGB 9254. Leukemia & lymphoma\| PubMed ID: 21275630	2011
Blockade of B7/CD28 in mixed lymphocyte reaction cultures results in the generation of alternatively activated macrophages, which suppress T-cell responses. Blood\| PubMed ID: 11830501	2002
CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11884439	2002
Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application. Blood\| PubMed ID: 11964299	2002
HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12023395	2002
cAMP inhibits both Ras and Rap1 activation in primary human T lymphocytes, but only Ras inhibition correlates with blockade of cell cycle progression. Blood\| PubMed ID: 12393539	2003
From genomics to cancer vaccines: patient-tailored or universal vaccines? Current opinion in molecular therapeutics\| PubMed ID: 12596359	2002
MUC1-like tandem repeat proteins are broadly immunogenic in cancer patients. Cancer immunity : a journal of the Academy of Cancer Immunology\| PubMed ID: 12747745	2003
Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma. British journal of haematology\| PubMed ID: 12786794	2003
The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells. Blood\| PubMed ID: 12869499	2003
Differential localization and function of ADP-ribosylation factor-6 in anergic human T cells: a potential marker for their identification. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12902467	2003
Autoantibodies frequently detected in patients with aplastic anemia. Blood\| PubMed ID: 12947009	2003
IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL. Blood\| PubMed ID: 14615384	2004
Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 14871958	2004
Autologous bone marrow transplantation for marginal zone non-Hodgkin's lymphoma. Leukemia & lymphoma\| PubMed ID: 15101717	2004
Correspondence re R. Lapointe et al., CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells. Cancer Res 2003;63:2... Cancer research\| PubMed ID: 15173021	2004
pH-triggered microparticles for peptide vaccination. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15294974	2004
Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells. The Journal of experimental medicine\| PubMed ID: 15353558	2004
Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-alpha/beta-inducible gene expression, without signif... Blood\| PubMed ID: 15358617	2005
Measuring T cell immunity to influenza vaccination in children after haemopoietic stem cell transplantation. British journal of haematology\| PubMed ID: 15491293	2004
Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia. Haematologica\| PubMed ID: 15590396	2004
Presence of anti-kinectin and anti-PMS1 antibodies in Japanese aplastic anaemia patients. British journal of haematology\| PubMed ID: 15638857	2005
Identification of a new HLA-A*0201-restricted cryptic epitope from CYP1B1. International journal of cancer. Journal international du cancer\| PubMed ID: 15688394	2005
Failure to define window of time for autologous tumor vaccination in patients with newly diagnosed or relapsed acute lymphoblastic leukemia. Experimental hematology\| PubMed ID: 15730852	2005
Increasing incidence of late second malignancies after conditioning with cyclophosphamide and total-body irradiation and autologous bone marrow transplantation for non-Hodgkin's lymphoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15753460	2005
Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia. Blood\| PubMed ID: 15920008	2005
Unexpected association between induction of immunity to the universal tumor antigen CYP1B1 and response to next therapy. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15958627	2005
Phase I/II combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-A2-restricted CAP-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastati... Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16115944	2005
Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia. Blood\| PubMed ID: 16131571	2005
Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockade of mTOR and NF-kappaB. Blood\| PubMed ID: 16141350	2006
Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity. Blood\| PubMed ID: 16239433	2006
Gene expression profiling identifies BAX-delta as a novel tumor antigen in acute lymphoblastic leukemia. Cancer research\| PubMed ID: 16267031	2005
CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants. Blood\| PubMed ID: 16357329	2006
Leukemia-stimulated bone marrow endothelium promotes leukemia cell survival. Experimental hematology\| PubMed ID: 16647567	2006
Efficient presentation of naturally processed HLA class I peptides by artificial antigen-presenting cells for the generation of effective antitumor responses. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16707591	2006
Identification of an immunogenic CD8+ T-cell epitope derived from gamma-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia. Blood\| PubMed ID: 16778141	2006
Long-lived antitumor CD8+ lymphocytes for adoptive therapy generated using an artificial antigen-presenting cell. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17363542	2007
Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 17697968	2007
Lee Marshall Nadler, MD: a conversation with the editor. Proceedings (Baylor University. Medical Center)\| PubMed ID: 17948113	2007
Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies. Blood\| PubMed ID: 18617635	2008
Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18641323	2008
CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 18765557	2008
Induction of alloanergy in human donor T cells without loss of pathogen or tumor immunity. Transplantation\| PubMed ID: 18813111	2008
Dissociation of its opposing immunologic effects is critical for the optimization of antitumor CD8+ T-cell responses induced by interleukin 21. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 18829491	2008
Cyclin D1-specific cytotoxic T lymphocytes are present in the repertoire of cancer patients: implications for cancer immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 18927298	2008
Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation. Science translational medicine\| PubMed ID: 20368155	2009
Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies. Cancer research\| PubMed ID: 20424114	2010
A panel of human cell-based artificial APC enables the expansion of long-lived antigen-specific CD4+ T cells restricted by prevalent HLA-DR alleles. International immunology\| PubMed ID: 21059769	2010
Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors. Experimental hematology\| PubMed ID: 21277936	2011
Establishment of antitumor memory in humans using in vitro-educated CD8+ T cells. Science translational medicine\| PubMed ID: 21525398	2011
Aberrant expression of functional BAFF-system receptors by malignant B-cell precursors impacts leukemia cell survival. PloS one\| PubMed ID: 21687682	2011
Induction of HLA-DP4-restricted anti-survivin Th1 and Th2 responses using an artificial antigen-presenting cell. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21705450	2011
IL-21 Can Supplement Suboptimal Lck-Independent MAPK Activation in a STAT-3-Dependent Manner in Human CD8+ T Cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22238455	2012
Ex vivo expansion of human CD8 T cells using autologous CD4 T cell help. PloS one\| PubMed ID: 22279573	2012