Yasuo Ihara

Graduate School of Brain Science, Doshisha University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 23	2019

Other Publications

Article	Year
Curcumin improves tau-induced neuronal dysfunction of nematodes. Neurobiology of aging\| PubMed ID: 26923403	2016
[Overview on Alzheimer's disease]. Rinsho shinkeigaku = Clinical neurology\| PubMed ID: 18210830	2007
GAB2 is not associated with late-onset Alzheimer's disease in Japanese. European journal of human genetics : EJHG\| PubMed ID: 18854865	2009
gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19828817	2009
Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 21554501	2011
The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer disease. Cold Spring Harbor perspectives in medicine\| PubMed ID: 22908190	2012
Suspected limited efficacy of γ-secretase modulators. Neurobiology of aging\| PubMed ID: 23058852	2013
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PloS one\| PubMed ID: 23565137	2013
Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3. The Journal of biological chemistry\| PubMed ID: 23723072	2013
Substrate ectodomain is critical for substrate preference and inhibition of γ-secretase. Nature communications\| PubMed ID: 24108142	2013
γ-Secretase associated with lipid rafts: multiple interactive pathways in the stepwise processing of β-carboxyl-terminal fragment. The Journal of biological chemistry\| PubMed ID: 24375443	2014
The homologous carboxyl-terminal domains of microtubule-associated protein 2 and TAU induce neuronal dysfunction and have differential fates in the evolution of neurofibrillary tangles. PloS one\| PubMed ID: 24587039	2014
Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population. Journal of Alzheimer's disease : JAD\| PubMed ID: 24762945	2014
Immunostaining of oxidized DJ-1 in human and mouse brains. Journal of neuropathology and experimental neurology\| PubMed ID: 24918637	2014
Identification of key amino acids responsible for the distinct aggregation properties of microtubule-associated protein 2 and tau. Journal of neurochemistry\| PubMed ID: 26134402	2015
The A673T mutation in the amyloid precursor protein reduces the production of β-amyloid protein from its β-carboxyl terminal fragment in cells. Acta neuropathologica communications\| PubMed ID: 26531305	2015
Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups. Nature communications\| PubMed ID: 26671725	2015
Alanine substitutions in the GXXXG motif alter C99 cleavage by γ-secretase but not its dimerization. Journal of neurochemistry\| PubMed ID: 28032911	2017
Semagacestat Is a Pseudo-Inhibitor of γ-Secretase. Cell reports\| PubMed ID: 28978478	2017
Distinct deposition of amyloid-β species in brains with Alzheimer's disease pathology visualized with MALDI imaging mass spectrometry. Acta neuropathologica communications\| PubMed ID: 29037261	2017
Imbalanced Expression of Tau and Tubulin Induces Neuronal Dysfunction in Models of Tauopathy. Frontiers in neuroscience\| PubMed ID: 29973863	2018