Jean-Philippe Julien

Program in Molecular Medicine, The Hospital for Sick Children Research Institute

Affiliated withThe Hospital for Sick Children Research Institute University of Toronto

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2018

Other Publications

Article	Year
Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25422458	2014
Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer. PLoS pathogens\| PubMed ID: 25807248	2015
Origins of a Vaccine-Induced, Human Anti-HIV-1 Antibody. EBioMedicine\| PubMed ID: 26288832	2015
Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26372963	2015
EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis. PloS one\| PubMed ID: 26934472	2016
HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen. Science (New York, N.Y.)\| PubMed ID: 27013733	2016
Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. PLoS pathogens\| PubMed ID: 27560183	2016
Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27798168	2016
Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 28003379	2017
Molecular basis of human CD22 function and therapeutic targeting. Nature communications\| PubMed ID: 28970495	2017
Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nature communications\| PubMed ID: 29146922	2017
Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection. The Journal of experimental medicine\| PubMed ID: 29167197	2018
Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies. Immunity\| PubMed ID: 29195810	2017
Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. Journal of molecular biology\| PubMed ID: 29277294	2018
Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11. Journal of virology\| PubMed ID: 29618644	2018
Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies. Immunity\| PubMed ID: 29768173	2018
Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science (New York, N.Y.)\| PubMed ID: 29880723	2018