Peter Neubauer

Chair of Bioprocess Engineering, Technische Universität Berlin

Affiliated withTechnische Universität Berlin

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2019

Other Publications

Article	Year
Norvaline is accumulated after a down-shift of oxygen in Escherichia coli W3110. Microbial cell factories\| PubMed ID: 18940002	2008
Enzyme controlled glucose auto-delivery for high cell density cultivations in microplates and shake flasks. Microbial cell factories\| PubMed ID: 19017379	2008
A novel fed-batch based cultivation method provides high cell-density and improves yield of soluble recombinant proteins in shaken cultures. Microbial cell factories\| PubMed ID: 20167131	2010
Scale-down simulators for metabolic analysis of large-scale bioprocesses. Current opinion in biotechnology\| PubMed ID: 20185293	2010
Novel approach of high cell density recombinant bioprocess development: optimisation and scale-up from microliter to pilot scales while maintaining the fed-batch cultivation mode of E. coli ... Microbial cell factories\| PubMed ID: 20487563	2010
Quality control of inclusion bodies in Escherichia coli. Microbial cell factories\| PubMed ID: 20509924	2010
High cell density cultivation and recombinant protein production with Escherichia coli in a rocking-motion-type bioreactor. Microbial cell factories\| PubMed ID: 20509968	2010
Sandwich ELISA for quantitative detection of human collagen prolyl 4-hydroxylase. Microbial cell factories\| PubMed ID: 20565744	2010
Complete genome sequence of the lytic Pseudomonas fluorescens phage ϕIBB-PF7A. Virology journal\| PubMed ID: 21439081	2011
Reducing conditions are the key for efficient production of active ribonuclease inhibitor in Escherichia coli. Microbial cell factories\| PubMed ID: 21554746	2011
Enhanced growth and recombinant protein production of Escherichia coli by a perfluorinated oxygen carrier in miniaturized fed-batch cultures. Microbial cell factories\| PubMed ID: 21708024	2011
Two-compartment method for determination of the oxygen transfer rate with electrochemical sensors based on sulfite oxidation. Biotechnology journal\| PubMed ID: 21751399	2011
A two-compartment bioreactor system made of commercial parts for bioprocess scale-down studies: impact of oscillations on Bacillus subtilis fed-batch cultivations. Biotechnology journal\| PubMed ID: 21751400	2011
Heterologous production of active ribonuclease inhibitor in Escherichia coli by redox state control and chaperonin coexpression. Microbial cell factories\| PubMed ID: 21824411	2011
High-temperature cultivation and 5' mRNA optimization are key factors for the efficient overexpression of thermostable Deinococcus geothermalis purine nucleoside phosphorylase in Escherichia... Journal of biotechnology\| PubMed ID: 21871934	2011
Glucose-limited high cell density cultivations from small to pilot plant scale using an enzyme-controlled glucose delivery system. New biotechnology\| PubMed ID: 22100433	2012
High-yield production of biologically active recombinant protein in shake flask culture by combination of enzyme-based glucose delivery and increased oxygen transfer. Microbial cell factories\| PubMed ID: 22152005	2011
Enhanced plasmid production in miniaturized high-cell-density cultures of Escherichia coli supported with perfluorinated oxygen carrier. Bioprocess and biosystems engineering\| PubMed ID: 23178986	2013
Recombinant purine nucleoside phosphorylases from thermophiles: preparation, properties and activity towards purine and pyrimidine nucleosides. The FEBS journal\| PubMed ID: 23332162	2013
Recombinant protein production: a comparative view on host physiology (Laupheim, Germany, March 2013). New biotechnology\| PubMed ID: 23770265	2013
Cultivation of marine microorganisms in single-use systems. Advances in biochemical engineering/biotechnology\| PubMed ID: 23893044	2014
Effect of culture medium, host strain and oxygen transfer on recombinant Fab antibody fragment yield and leakage to medium in shaken E. coli cultures. Microbial cell factories\| PubMed ID: 23895637	2013
Lactose autoinduction with enzymatic glucose release: characterization of the cultivation system in bioreactor. Protein expression and purification\| PubMed ID: 24215862	2014
Reconstituted biosynthesis of the nonribosomal macrolactone antibiotic valinomycin in Escherichia coli. ACS synthetic biology\| PubMed ID: 24350980	2014
Process inhomogeneity leads to rapid side product turnover in cultivation of Corynebacterium glutamicum. Microbial cell factories\| PubMed ID: 24410842	2014
Enhanced production of the nonribosomal peptide antibiotic valinomycin in Escherichia coli through small-scale high cell density fed-batch cultivation. Applied microbiology and biotechnology\| PubMed ID: 24419900	2014
Quantitative and sensitive RNA based detection of Bacillus spores. Frontiers in microbiology\| PubMed ID: 24653718	2014
Escherichia coli as a cell factory for heterologous production of nonribosomal peptides and polyketides. New biotechnology\| PubMed ID: 24704144	2014
Identification and characterization of RNA guanine-quadruplex binding proteins. Nucleic acids research\| PubMed ID: 24771345	2014
Investigation of Phenolic Acids in Suspension Cultures of Vitis vinifera Stimulated with Indanoyl-Isoleucine, N-Linolenoyl-L-Glutamine, Malonyl Coenzyme A and Insect Saliva. Metabolites\| PubMed ID: 24957372	2012
Robotic platform for parallelized cultivation and monitoring of microbial growth parameters in microwell plates. Journal of laboratory automation\| PubMed ID: 25208534	2014
Type II thioesterase improves heterologous biosynthesis of valinomycin in Escherichia coli. Journal of biotechnology\| PubMed ID: 25449019	2015
Toward Microbioreactor Arrays: A Slow-Responding Oxygen Sensor for Monitoring of Microbial Cultures in Standard 96-Well Plates. Journal of laboratory automation\| PubMed ID: 25720599	2015
Response of Corynebacterium glutamicum exposed to oscillating cultivation conditions in a two- and a novel three-compartment scale-down bioreactor. Biotechnology and bioengineering\| PubMed ID: 25728062	2015
Structure-based directed evolution of a monomeric triosephosphate isomerase: toward a pentose sugar isomerase. Protein engineering, design & selection : PEDS\| PubMed ID: 25767111	2015
Scale-up bioprocess development for production of the antibiotic valinomycin in Escherichia coli based on consistent fed-batch cultivations. Microbial cell factories\| PubMed ID: 26063334	2015
An improved HPLC-DAD method for clavulanic acid quantification in fermentation broths of Streptomyces clavuligerus. Journal of pharmaceutical and biomedical analysis\| PubMed ID: 26760242	2016
Inversion of the stereochemical configuration (3S, 5S)-clavaminic acid into (3R, 5R)-clavulanic acid: A computationally-assisted approach based on experimental evidence. Journal of theoretical biology\| PubMed ID: 26835563	2016
Lanthipeptides: chemical synthesis versus in vivo biosynthesis as tools for pharmaceutical production. Microbial cell factories\| PubMed ID: 27267232	2016
Crystal structures of two monomeric triosephosphate isomerase variants identified via a directed-evolution protocol selecting for L-arabinose isomerase activity. Acta crystallographica. Section F, Structural biology communications\| PubMed ID: 27303904	2016
The fed-batch principle for the molecular biology lab: controlled nutrient diets in ready-made media improve production of recombinant proteins in Escherichia coli. Microbial cell factories\| PubMed ID: 27317421	2016
Life cycle assessment of flexibly fed biogas processes for an improved demand-oriented biogas supply. Bioresource technology\| PubMed ID: 27522120	2016
Pharmacological and pharmacokinetic properties of lanthipeptides undergoing clinical studies. Biotechnology letters\| PubMed ID: 28044226	2017
Erratum to: Pharmacological and pharmacokinetic properties of lanthipeptides undergoing clinical studies. Biotechnology letters\| PubMed ID: 28155176	2017
Micro-Electromechanical Affinity Sensor for the Monitoring of Glucose in Bioprocess Media. International journal of molecular sciences\| PubMed ID: 28594350	2017
Sterol synthesis and cell size distribution under oscillatory growth conditions in Saccharomyces cerevisiae scale-down cultivations. Yeast (Chichester, England)\| PubMed ID: 28940694	2018
Bare laser-synthesized Au-based nanoparticles as nondisturbing surface-enhanced Raman scattering probes for bacteria identification. Journal of biophotonics\| PubMed ID: 29388744	2018
Streptomyces clavuligerus shows a strong association between TCA cycle intermediate accumulation and clavulanic acid biosynthesis. Applied microbiology and biotechnology\| PubMed ID: 29523936	2018
How scalable and suitable are single-use bioreactors? Current opinion in biotechnology\| PubMed ID: 29753977	2018
Real-time monitoring of the budding index in Saccharomyces cerevisiae batch cultivations with in situ microscopy. Microbial cell factories\| PubMed ID: 29764434	2018
Importance of the cultivation history for the response of Escherichia coli to oscillations in scale-down experiments. Bioprocess and biosystems engineering\| PubMed ID: 29808419	2018
Synthesis of non-canonical branched-chain amino acids in Escherichia coli and approaches to avoid their incorporation into recombinant proteins. Current opinion in biotechnology\| PubMed ID: 29870877	2018
Comparison of time-gated surface-enhanced raman spectroscopy (TG-SERS) and classical SERS based monitoring of Escherichia coli cultivation samples. Biotechnology progress\| PubMed ID: 29882305	2018
An observational study of ballooning in large spiders: Nanoscale multifibers enable large spiders' soaring flight. PLoS biology\| PubMed ID: 29902191	2018
Application of Continuous Culture Methods to Recombinant Protein Production in Microorganisms. Microorganisms\| PubMed ID: 29933583	2018
Automated Cell Treatment for Competence and Transformation of in a High-Throughput Quasi-Turbidostat Using Microtiter Plates. Microorganisms\| PubMed ID: 29941834	2018
Bioinspired Designs, Molecular Premise and Tools for Evaluating the Ecological Importance of Antimicrobial Peptides. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 29996512	2018
Heterologous Biosynthesis, Modifications and Structural Characterization of Ruminococcin-A, a Lanthipeptide From the Gut Bacterium E1, in . Frontiers in microbiology\| PubMed ID: 30093894	2018
Rocking Aspergillus: morphology-controlled cultivation of Aspergillus niger in a wave-mixed bioreactor for the production of secondary metabolites. Microbial cell factories\| PubMed ID: 30129427	2018
CFD predicted pH gradients in lactic acid bacteria cultivations. Biotechnology and bioengineering\| PubMed ID: 30450609	2019
Accelerated Bioprocess Development of Endopolygalacturonase-Production with Using Multivariate Prediction in a 48 Mini-Bioreactor Automated Platform. Bioengineering (Basel, Switzerland)\| PubMed ID: 30469407	2018
Electrooptical Determination of Polarizability for On-Line Viability and Vitality Quantification of Cultures. Frontiers in bioengineering and biotechnology\| PubMed ID: 30564571	2018
Degradation Kinetics of Clavulanic Acid in Fermentation Broths at Low Temperatures. Antibiotics (Basel, Switzerland)\| PubMed ID: 30658482	2019
Carboxylic acid consumption and production by Corynebacterium glutamicum. Biotechnology progress\| PubMed ID: 30851150	2019
Antibacterial and anticancer activities of orphan biosynthetic gene clusters from Atlantis II Red Sea brine pool. Microbial cell factories\| PubMed ID: 30885206	2019
Reproduction of Large-Scale Bioreactor Conditions on Microfluidic Chips. Microorganisms\| PubMed ID: 31010155	2019
Construction and characterization of broad-host-range reporter plasmid suitable for on-line analysis of bacterial host responses related to recombinant protein production. Microbial cell factories\| PubMed ID: 31064376	2019
Monte Carlo Simulations for the Analysis of Non-linear Parameter Confidence Intervals in Optimal Experimental Design. Frontiers in bioengineering and biotechnology\| PubMed ID: 31179278	2019
A UV/Vis Spectroscopy-Based Assay for Monitoring of Transformations Between Nucleosides and Nucleobases. Methods and protocols\| PubMed ID: 31311105	2019
A model-based framework for parallel scale-down fed-batch cultivations in mini-bioreactors for accelerated phenotyping. Biotechnology and bioengineering\| PubMed ID: 31317526	2019
Data of clavulanic acid and clavulanate-imidazole stability at low temperatures. Data in brief\| PubMed ID: 31372423	2019
Monitoring of Polyhydroxyalkanoate (PHA) Production during High-Cell-Density Plant Oil Cultivations Using Photon Density Wave Spectroscopy. Bioengineering (Basel, Switzerland)\| PubMed ID: 31546779	2019
Characterization of the Metabolic Response of to Shear Stress in Stirred Tanks and Single-Use 2D Rocking Motion Bioreactors for Clavulanic Acid Production. Antibiotics (Basel, Switzerland)\| PubMed ID: 31569725	2019
Bioprocess Development for Lantibiotic Ruminococcin-A Production in and Kinetic Insights Into LanM Enzymes Catalysis. Frontiers in microbiology\| PubMed ID: 31572338	2019
Fungi as source for new bio-based materials: a patent review. Fungal biology and biotechnology\| PubMed ID: 31673396	2019