Noah Weisleder

Department of Physiology and Biophysics, Robert Wood Johnson Medical School

Affiliated withRobert Wood Johnson Medical School The Ohio State University Wexner Medical Center The Ohio State University

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 17	2011
Publication title Cited by 15	2014
Publication title Cited by 82	2014

Other Publications

Article	Year
Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14715896	2004
Cardiomyocyte-specific desmin rescue of desmin null cardiomyopathy excludes vascular involvement. Journal of molecular and cellular cardiology\| PubMed ID: 14734054	2004
Structural and functional roles of desmin in mouse skeletal muscle during passive deformation. Biophysical journal\| PubMed ID: 15111414	2004
Alterations in the heart mitochondrial proteome in a desmin null heart failure model. Journal of molecular and cellular cardiology\| PubMed ID: 15733906	2005
Uncontrolled calcium sparks act as a dystrophic signal for mammalian skeletal muscle. Nature cell biology\| PubMed ID: 15834406	2005
Enhanced resistance to fatigue and altered calcium handling properties of sarcalumenin knockout mice. Physiological genomics\| PubMed ID: 15998745	2005
Uncoupling store-operated Ca2+ entry and altered Ca2+ release from sarcoplasmic reticulum through silencing of junctophilin genes. Biophysical journal\| PubMed ID: 16565048	2006
Ca2+ sparks as a plastic signal for skeletal muscle health, aging, and dystrophy. Acta pharmacologica Sinica\| PubMed ID: 16787561	2006
Muscle aging is associated with compromised Ca2+ spark signaling and segregated intracellular Ca2+ release. The Journal of cell biology\| PubMed ID: 16943181	2006
Azumolene inhibits a component of store-operated calcium entry coupled to the skeletal muscle ryanodine receptor. The Journal of biological chemistry\| PubMed ID: 16945924	2006
Systemic ablation of RyR3 alters Ca2+ spark signaling in adult skeletal muscle. Cell calcium\| PubMed ID: 17412417	2007
Mutations in JPH2-encoded junctophilin-2 associated with hypertrophic cardiomyopathy in humans. Journal of molecular and cellular cardiology\| PubMed ID: 17509612	2007
TRIC channels are essential for Ca2+ handling in intracellular stores. Nature\| PubMed ID: 17611541	2007
The tail-anchoring domain of Bfl1 and HCCS1 targets mitochondrial membrane permeability to induce apoptosis. Journal of cell science\| PubMed ID: 17666431	2007
Immuno-proteomic approach to excitation--contraction coupling in skeletal and cardiac muscle: molecular insights revealed by the mitsugumins. Cell calcium\| PubMed ID: 18061662	2008
Altered Ca2+ sparks in aging skeletal and cardiac muscle. Ageing research reviews\| PubMed ID: 18272434	2008
Caveolae/caveolin-1 are important modulators of store-operated calcium entry in Hs578/T breast cancer cells. Journal of pharmacological sciences\| PubMed ID: 18296864	2008
Compromised store-operated Ca2+ entry in aged skeletal muscle. Aging cell\| PubMed ID: 18505477	2008
A missense mutation in desmin tail domain linked to human dilated cardiomyopathy promotes cleavage of the head domain and abolishes its Z-disc localization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 18539904	2008
MG53 regulates membrane budding and exocytosis in muscle cells. The Journal of biological chemistry\| PubMed ID: 19029292	2009
MG53 nucleates assembly of cell membrane repair machinery. Nature cell biology\| PubMed ID: 19043407	2009
The amino-terminal peptide of Bax perturbs intracellular Ca2+ homeostasis to enhance apoptosis in prostate cancer cells. American journal of physiology. Cell physiology\| PubMed ID: 19091958	2009
Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin. The Journal of biological chemistry\| PubMed ID: 19380584	2009
Mitsugumin 53 (MG53) facilitates vesicle trafficking in striated muscle to contribute to cell membrane repair. Communicative & integrative biology\| PubMed ID: 19641737	2009
S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle. The Biochemical journal\| PubMed ID: 20095964	2010
Repression of cardiac phospholamban gene expression is mediated by thyroid hormone receptor-{alpha}1 and involves targeted covalent histone modifications. Endocrinology\| PubMed ID: 20392835	2010
Cardioprotection of ischemia/reperfusion injury by cholesterol-dependent MG53-mediated membrane repair. Circulation research\| PubMed ID: 20466981	2010
MG53 constitutes a primary determinant of cardiac ischemic preconditioning. Circulation\| PubMed ID: 20516375	2010
Increased store-operated Ca2+ entry in skeletal muscle with reduced calsequestrin-1 expression. Biophysical journal\| PubMed ID: 20816068	2010
Amphipathic tail-anchoring peptide and Bcl-2 homology domain-3 (BH3) peptides from Bcl-2 family proteins induce apoptosis through different mechanisms. The Journal of biological chemistry\| PubMed ID: 21189256	2011
Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling. Circulation. Heart failure\| PubMed ID: 21216834	2011
Polymerase transcriptase release factor (PTRF) anchors MG53 protein to cell injury site for initiation of membrane repair. The Journal of biological chemistry\| PubMed ID: 21343302	2011
Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch. Journal of neuropathology and experimental neurology\| PubMed ID: 21412170	2011
A versatile single-plasmid system for tissue-specific and inducible control of gene expression in transgenic mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 21518849	2011
Redox-dependent oligomerization through a leucine zipper motif is essential for MG53-mediated cell membrane repair. American journal of physiology. Cell physiology\| PubMed ID: 21525429	2011
Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals. Cell research\| PubMed ID: 21556035	2011
Store-operated Ca(2+) entry (SOCE) contributes to normal skeletal muscle contractility in young but not in aged skeletal muscle. Aging\| PubMed ID: 21666285	2011
Mitochondrial calcium uptake regulates rapid calcium transients in skeletal muscle during excitation-contraction (E-C) coupling. The Journal of biological chemistry\| PubMed ID: 21795684	2011
Disrupted membrane structure and intracellular CaÂ²âº signaling in adult skeletal muscle with acute knockdown of Bin1. PloS one\| PubMed ID: 21984944	2011
Store-operated calcium entry is present in HL-1 cardiomyocytes and contributes to resting calcium. Biochemical and biophysical research communications\| PubMed ID: 22079292	2011
Detection of calcium sparks in intact and permeabilized skeletal muscle fibers. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22130850	2012
Nonmuscle myosin IIA facilitates vesicle trafficking for MG53-mediated cell membrane repair. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22253476	2012
Enhancing Muscle Membrane Repair by Gene Delivery of MG53 Ameliorates Muscular Dystrophy and Heart Failure in Î´-Sarcoglycan-deficient Hamsters. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22314291	2012
Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy. Science translational medicine\| PubMed ID: 22723464	2012
Poloxamer 188 (p188) as a membrane resealing reagent in biomedical applications. Recent patents on biotechnology\| PubMed ID: 23092436	2012
Orai1 mediates exacerbated Ca(2+) entry in dystrophic skeletal muscle. PloS one\| PubMed ID: 23185465	2012
Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle. The Journal of biological chemistry\| PubMed ID: 23223241	2013
A dual mode pulsed electro-magnetic cell stimulator produces acceleration of myogenic differentiation. Recent patents on biotechnology\| PubMed ID: 23445453	2013
TRIM proteins in therapeutic membrane repair of muscular dystrophy. JAMA neurology\| PubMed ID: 23699904	2013
Novel excitation-contraction coupling related genes reveal aspects of muscle weakness beyond atrophy-new hopes for treatment of musculoskeletal diseases. Frontiers in physiology\| PubMed ID: 24600395	2014