Alan W. Flake

Alan W. Flake

Division of General, Children's Hospital of Philadelphia

Affiliated withChildren's Hospital of Philadelphia

Research Area

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JoVE Journal Publications

ArticleTotal : 1
Year
Intravenous and Intra-amniotic <em>In Utero</em> Transplantation in the Murine Model
Publication title

Cited by 11

2018

Other Publications

Article
Year
In utero hematopoietic stem cell transplantation. A status report.

JAMA| PubMed ID: 9302247

1997
In utero transplantation for thalassemia.

Annals of the New York Academy of Sciences| PubMed ID: 9668552

1998
The current status and future potential of fetal intervention: image is everything.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society| PubMed ID: 10091869

1999
1999
In utero stem cell transplantation for the treatment of genetic diseases.

Schweizerische medizinische Wochenschrift| PubMed ID: 10603645

1999
The natural history of prenatally diagnosed conjoined twins.

Journal of pediatric surgery| PubMed ID: 11877639

2002
2002
The EXIT procedure: experience and outcome in 31 cases.

Journal of pediatric surgery| PubMed ID: 11877660

2002
Bone marrow tissue engineering.

Tissue engineering| PubMed ID: 11886662

2002
2002
2002
2002
2002
The ex-utero intrapartum treatment.

Current opinion in pediatrics| PubMed ID: 12130912

2002
2002
Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 12231171

2002
Genetic therapies for the fetus.

Clinical obstetrics and gynecology| PubMed ID: 12370608

2002
2003
Management of congenital lung lesions.

Seminars in pediatric surgery| PubMed ID: 12520469

2003
Surgery in the human fetus: the future.

The Journal of physiology| PubMed ID: 12562950

2003
Temporary tracheal occlusion in fetal sheep with lung hypoplasia does not improve postnatal lung function.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 12571135

2003
2003
2003
2003
2003
2003
Stem cell and genetic therapies for the fetus.

Seminars in pediatric surgery| PubMed ID: 12961115

2003
Fetal myelomeningocele repair: short-term clinical outcomes.

American journal of obstetrics and gynecology| PubMed ID: 14520222

2003
2003
2003
2004
2004
2004
2004
Right congenital diaphragmatic hernia: Prenatal assessment and outcome.

Journal of pediatric surgery| PubMed ID: 15017545

2004
2004
Mesenchymal stem cells: paradoxes of passaging.

Experimental hematology| PubMed ID: 15145209

2004
2004
2004
2004
Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research| PubMed ID: 15355914

2004
Heregulin ameliorates the dystrophic phenotype in mdx mice.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 15365169

2004
2005
Reproductive outcomes after pregnancy complicated by maternal-fetal surgery.

American journal of obstetrics and gynecology| PubMed ID: 15507978

2004
2005
2004
2004
In utero stem cell transplantation.

Best practice & research. Clinical obstetrics & gynaecology| PubMed ID: 15582548

2004
2005
Management of fetal mediastinal teratoma.

Journal of pediatric surgery| PubMed ID: 15868589

2005
2005
2005
2006
Severe pulmonary hypoplasia associated with giant cervical teratomas.

Journal of pediatric surgery| PubMed ID: 16410139

2006
2006
2006
2006
2006
2006
2007
2006
2006
Diagnosis and characterization of fetal sacrococcygeal teratoma with prenatal MRI.

AJR. American journal of roentgenology| PubMed ID: 16985105

2006
2006
2007
2006
Targeted gene transfer to fetal rat lung interstitium by ultrasound-guided intrapulmonary injection.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 17235312

2007
Gene transfer to ocular stem cells by early gestational intraamniotic injection of lentiviral vector.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 17245352

2007
Murine bone marrow stromal progenitor cells elicit an in vivo cellular and humoral alloimmune response.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation| PubMed ID: 17382248

2007
Enhanced epithelial gap closure and increased angiogenesis in wounds of diabetic mice treated with adult murine bone marrow stromal progenitor cells.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society| PubMed ID: 17537122

2007
2007
2007
Persistent expression of hF.IX After tolerance induction by in utero or neonatal administration of AAV-1-F.IX in hemophilia B mice.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 17565352

2007
2006
2007
2007
2008
2008
Pulmonary vascular malformations.

Seminars in pediatric surgery| PubMed ID: 18158137

2008
2008
2008
2008
2008
2008
2008
Cystic adenomatoid malformations are induced by localized FGF10 overexpression in fetal rat lung.

American journal of respiratory cell and molecular biology| PubMed ID: 18421016

2008
In utero hematopoietic stem cell transplantation: progress toward clinical application.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation| PubMed ID: 18541191

2008
Repair of indirect inguinal hernias by "laparoscopic joining of the edges".

Surgical laparoscopy, endoscopy & percutaneous techniques| PubMed ID: 18574416

2008
Apoptotic cell-mediated immunoregulation of dendritic cells does not require iC3b opsonization.

Journal of immunology (Baltimore, Md. : 1950)| PubMed ID: 18713972

2008
2008
2008
Correction of ADAMTS13 deficiency by in utero gene transfer of lentiviral vector encoding ADAMTS13 genes.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 18957966

2009
2008
2009
2009
Haploidentical in utero hematopoietic cell transplantation improves phenotype and can induce tolerance for postnatal same-donor transplants in the canine leukocyte adhesion deficiency model.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation| PubMed ID: 19203720

2009
In utero meconium passage in fetuses and newborns with myelomeningocele.

Journal of neurosurgery. Pediatrics| PubMed ID: 19278315

2009
Stem cell and genetic therapies for the fetus.

Seminars in fetal & neonatal medicine| PubMed ID: 19540822

2010
Prenatal stem cell transplantation and gene therapy.

Clinics in perinatology| PubMed ID: 19559331

2009
2009
2010
2010
2010
2010
2010
2010
2010
Predicting the severity of congenital high airway obstruction syndrome.

Journal of pediatric surgery| PubMed ID: 20713212

2010
2010
2010
Fetal surgery: progress and perspectives.

Advances in pediatrics| PubMed ID: 21056747

2010
2011
2011
Laparoscopic hepaticoduodenostomy versus open hepaticoduodenostomy for reconstruction after resection of choledochal cyst.

Journal of laparoendoscopic & advanced surgical techniques. Part A| PubMed ID: 21443442

2011
2011
2011
In vivo Differentiation Potential of Mesenchymal Stem Cells: Prenatal and Postnatal Model Systems.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie| PubMed ID: 21547121

2008
2011
2012
2012
2008
Patch repair for congenital diaphragmatic hernia: is it really a problem?

Journal of pediatric surgery| PubMed ID: 22498374

2012
2012
Maternal-fetal surgery for structural malformations.

Best practice & research. Clinical obstetrics & gynaecology| PubMed ID: 22542765

2012
2012
Use of manipulated stem cells for prenatal therapy.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 22648772

2012
Animal models for prenatal gene therapy: rodent models for prenatal gene therapy.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 22648774

2012
2012
2012
2013
2012
2013
Stem cell and genetic therapies for the fetus.

Seminars in pediatric surgery| PubMed ID: 23395147

2013
2013
Fetal surgical intervention: progress and perspectives.

Pediatric surgery international| PubMed ID: 23552956

2013
The effects of fetal surgery on retinopathy of prematurity development.

Ophthalmology and eye diseases| PubMed ID: 23861606

2009
2013
2014
Open fetal surgery for central bronchial atresia.

Fetal diagnosis and therapy| PubMed ID: 24457616

2014
2014
2014
2014
2014
In utero stem cell and gene therapy: current status and future perspectives.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie| PubMed ID: 24945440

2014
2015
2015
2015
Percutaneous minimal-access fetoscopic surgery for myelomeningocele - not so minimal!

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology| PubMed ID: 25363896

2014
2014
Pulmonary hypertension in giant omphalocele infants.

Journal of pediatric surgery| PubMed ID: 25487480

2014
2015
2015
2015
2015
2015
2015
2015
2015
2015
2015
2015
2015
2014
2015
2015
2015
In utero stem cell transplantation and gene therapy: Recent progress and the potential for clinical application.

Best practice & research. Clinical obstetrics & gynaecology| PubMed ID: 26483174

2016
Experience with Thoracoscopic Repair of Long Gap Esophageal Atresia in Neonates.

Journal of laparoendoscopic & advanced surgical techniques. Part A| PubMed ID: 26485521

2015
2016
2016
Delayed abdominal closure after congenital diaphragmatic hernia repair.

Journal of pediatric surgery| PubMed ID: 26653950

2016
2016
The Intravenous Route of Injection Optimizes Engraftment and Survival in the Murine Model of In Utero Hematopoietic Cell Transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation| PubMed ID: 26797401

2016
2016
Vector serotype screening for use in ovine perinatal lung gene therapy.

Journal of pediatric surgery| PubMed ID: 27032612

2016
2016
2016
2016
2016
2017
2016
Prenatal growth characteristics of lymphatic malformations.

Journal of pediatric surgery| PubMed ID: 27836363

2017
2016
2017
2017
2018
2017
Acceptability of In Utero Hematopoietic Cell Transplantation for Sickle Cell Disease.

Medical decision making : an international journal of the Society for Medical Decision Making| PubMed ID: 28490230

2017
Responsible surgical innovation and research in maternal-fetal surgery.

Seminars in fetal & neonatal medicine| PubMed ID: 28551276

2017
2017
2018
2018
Fetal intervention: Improving evidence and expanding applications.

Seminars in fetal & neonatal medicine| PubMed ID: 29037820

2017
2017
2017
Short-Term Neurodevelopmental Outcome in Congenital Diaphragmatic Hernia: The Impact of Extracorporeal Membrane Oxygenation and Timing of Repair.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies| PubMed ID: 29303891

2018
Rate and Risk Factors Associated with Autism Spectrum Disorder in Congenital Diaphragmatic Hernia.

Journal of autism and developmental disorders| PubMed ID: 29383650

2018
2018
2018
2018
2018
2018
2018
2018
Preclinical Canine Model of Graft-versus-Host Disease after In Utero Hematopoietic Cell Transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation| PubMed ID: 29802901

2018
Reduced oxygen concentration for the resuscitation of infants with congenital diaphragmatic hernia.

Journal of perinatology : official journal of the California Perinatal Association| PubMed ID: 29887609

2018
Fetal surgery for spina bifida aperta.

Archives of disease in childhood. Fetal and neonatal edition| PubMed ID: 30006470

2018
Congenital pulmonary airway malformation: advances and controversies.

The Lancet. Child & adolescent health| PubMed ID: 30169300

2018