Yongliang Zhang

Department of Microbiology and Immunology, National University of Singapore

Affiliated withNational University of Singapore China Agricultural University

Research Area

Biography

I got the Ph. D degree in China Agricultural University on 2010. From then on, I continued performing research in China Agricultural University, and worked as an assistant professor, associate professor and Professor up to now. During this period, I had gone to UC Berkeley and UC Davis to work as a visiting scholar. Currently, I mainly focus on the study of virus-host interactions, R gene-mediated resistance against virus and plant virus-based vector development.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 1	2018
Publication title Cited by 37	2020

Other Publications

Article	Year
Production of transgenic pigs mediated by pseudotyped lentivirus and sperm. PloS one\| PubMed ID: 22536374	2012
Molecular cloning and ontogenesis expression of fatty acid transport protein-1 in yellow-feathered broilers. Journal of genetics and genomics = Yi chuan xue bao\| PubMed ID: 18571120	2008
Development of Tobacco necrosis virus A as a vector for efficient and stable expression of FMDV VP1 peptides. Plant biotechnology journal\| PubMed ID: 20331532	2010
Global comparison of gene expression profiles between intramuscular and subcutaneous adipocytes of neonatal landrace pig using microarray. Meat science\| PubMed ID: 20573458	2010
Oral administration of plant-based rotavirus VP6 induces antigen-specific IgAs, IgGs and passive protection in mice. Vaccine\| PubMed ID: 20637305	2010
A comprehensive expression profile of microRNAs in porcine pituitary. PloS one\| PubMed ID: 21969866	2011
Regulation of leucine catabolism by metabolic fuels in mammary epithelial cells. Amino acids\| PubMed ID: 22543725	2012
Nutritional and regulatory role of branched-chain amino acids in lactation. Frontiers in bioscience (Landmark edition)\| PubMed ID: 22652809	2012
Hormonal regulation of leucine catabolism in mammary epithelial cells. Amino acids\| PubMed ID: 22707151	2013
Effects of "Bioactive" amino acids leucine, glutamate, arginine and tryptophan on feed intake and mRNA expression of relative neuropeptides in broiler chicks. Journal of animal science and biotechnology\| PubMed ID: 22958345	2012
Validation of reference genes for gene expression studies in virus-infected Nicotiana benthamiana using quantitative real-time PCR. PloS one\| PubMed ID: 23029521	2012
Fatty Acid and Transcriptome Profiling of Longissimus Dorsi Muscles between Pig Breeds Differing in Meat Quality. International journal of biological sciences\| PubMed ID: 23355796	2013
N-terminal basic amino acid residues of Beet black scorch virus capsid protein play a critical role in virion assembly and systemic movement. Virology journal\| PubMed ID: 23786675	2013
Glucose utilization, lipid metabolism and BMP-Smad signaling pathway of porcine intramuscular preadipocytes compared with subcutaneous preadipocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 23860035	2013
Tolerogenic vaccination reduced effector memory CD4 T cells and induced effector memory Treg cells for type I diabetes treatment. PloS one\| PubMed ID: 23894591	2013
Selection of reference genes for gene expression studies in virus-infected monocots using quantitative real-time PCR. Journal of biotechnology\| PubMed ID: 23954326	2013
MiRNA-181a regulates adipogenesis by targeting tumor necrosis factor-α (TNF-α) in the porcine model. PloS one\| PubMed ID: 24098322	2013
Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24248350	2013
Deep sequencing-based transcriptome profiling reveals comprehensive insights into the responses of Nicotiana benthamiana to beet necrotic yellow vein virus infections containing or lacking R... PloS one\| PubMed ID: 24416380	2014
Effect of diacylglycerol acyltransferase 2 overexpression in 3T3-L1 is associated to an increase in mono-unsaturated fatty acid accumulation. Journal of animal science and biotechnology\| PubMed ID: 24982757	2014
Differential regulation of proinflammatory cytokine expression by mitogen-activated protein kinases in macrophages in response to intestinal parasite infection. Infection and immunity\| PubMed ID: 25156742	2014
STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation. Cell research\| PubMed ID: 25412660	2014
Characterization of the complete genome of Barley yellow striate mosaic virus reveals a nested gene encoding a small hydrophobic protein. Virology\| PubMed ID: 25666524	2015
MAPK Phosphatase 7 Regulates T Cell Differentiation via Inhibiting ERK-Mediated IL-2 Expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25716993	2015
MAPK Phosphatase 5 Expression Induced by Influenza and Other RNA Virus Infection Negatively Regulates IRF3 Activation and Type I Interferon Response. Cell reports\| PubMed ID: 25772359	2015
Casein kinase II controls TBK1/IRF3 activation in IFN response against viral infection. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25810395	2015
MAP kinase phosphatase 2 regulates macrophage-adipocyte interaction. PloS one\| PubMed ID: 25816341	2015
Morphogenesis of Endoplasmic Reticulum Membrane-Invaginated Vesicles during Beet Black Scorch Virus Infection: Role of Auxiliary Replication Protein and New Implications of Three-Dimensional... Journal of virology\| PubMed ID: 25833056	2015
Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5. The Journal of biological chemistry\| PubMed ID: 25922079	2015
Phosphorylation of TGB1 by protein kinase CK2 promotes barley stripe mosaic virus movement in monocots and dicots. Journal of experimental botany\| PubMed ID: 25998907	2015
Phosphorylation of Beet black scorch virus coat protein by PKA is required for assembly and stability of virus particles. Scientific reports\| PubMed ID: 26108567	2015
Transcriptome Analysis of Beta macrocarpa and Identification of Differentially Expressed Transcripts in Response to Beet Necrotic Yellow Vein Virus Infection. PloS one\| PubMed ID: 26196682	2015
MAPK phosphatase 5 inhibits IRF3. Oncotarget\| PubMed ID: 26305722	2015
N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. Biochemical and biophysical research communications\| PubMed ID: 26365347	2015
Architecture of viral replication factories. Oncotarget\| PubMed ID: 26429866	2015
α-Lipoic Acids Promote the Protein Synthesis of C2C12 Myotubes by the TLR2/PI3K Signaling Pathway. Journal of agricultural and food chemistry\| PubMed ID: 26855124	2016
Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells. Biochemical and biophysical research communications\| PubMed ID: 26879142	2016
Capsules of virulent pneumococcal serotypes enhance formation of neutrophil extracellular traps during in vivo pathogenesis of pneumonia. Oncotarget\| PubMed ID: 27034012	2016
Enhanced Proliferation of Porcine Bone Marrow Mesenchymal Stem Cells Induced by Extracellular Calcium is Associated with the Activation of the Calcium-Sensing Receptor and ERK Signaling Path... Stem cells international\| PubMed ID: 27123007	2016
Regulatory Roles of MAPK Phosphatases in Cancer. Immune network\| PubMed ID: 27162525	2016
Alpha-ketoglutarate promotes skeletal muscle hypertrophy and protein synthesis through Akt/mTOR signaling pathways. Scientific reports\| PubMed ID: 27225984	2016
Epigallocatechin Gallate Reduces Slow-Twitch Muscle Fiber Formation and Mitochondrial Biosynthesis in C2C12 Cells by Repressing AMPK Activity and PGC-1α Expression. Journal of agricultural and food chemistry\| PubMed ID: 27420899	2016
The dipeptide Pro-Asp promotes IGF-1 secretion and expression in hepatocytes by enhancing JAK2/STAT5 signaling pathway. Molecular and cellular endocrinology\| PubMed ID: 27473671	2016
Monocyte-derived factors including PLA2G7 induced by macrophage-nasopharyngeal carcinoma cell interaction promote tumor cell invasiveness. Oncotarget\| PubMed ID: 27487154	2016
Ex Vivo and In Vivo Mice Models to Study Blastocystis spp. Adhesion, Colonization and Pathology: Closer to Proving Koch's Postulates. PloS one\| PubMed ID: 27508942	2016
Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27578867	2016
Vaccination with Astragalus and Ginseng Polysaccharides Improves Immune Response of Chickens against H5N1 Avian Influenza Virus. BioMed research international\| PubMed ID: 27597953	2016
Blomia tropicalis-Specific TCR Transgenic Th2 Cells Induce Inducible BALT and Severe Asthma in Mice by an IL-4/IL-13-Dependent Mechanism. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27733553	2016
Improved Pathogenicity of a Beet Black Scorch Virus Variant by Low Temperature and Co-infection with Its Satellite RNA. Frontiers in microbiology\| PubMed ID: 27867378	2016
Lauric Acid Stimulates Mammary Gland Development of Pubertal Mice through Activation of GPR84 and PI3K/Akt Signaling Pathway. Journal of agricultural and food chemistry\| PubMed ID: 27978622	2017
N-Oleoylglycine-Induced Hyperphagia Is Associated with the Activation of Agouti-Related Protein (AgRP) Neuron by Cannabinoid Receptor Type 1 (CB1R). Journal of agricultural and food chemistry\| PubMed ID: 28102080	2017
Characterization of faecal microbial communities of dairy cows fed diets containing ensiled Moringa oleifera fodder. Scientific reports\| PubMed ID: 28134261	2017
Dietary protein-induced hepatic IGF-1 secretion mediated by PPARγ activation. PloS one\| PubMed ID: 28257428	2017
The Barley stripe mosaic virus γb protein promotes chloroplast-targeted replication by enhancing unwinding of RNA duplexes. PLoS pathogens\| PubMed ID: 28388677	2017
Phytol Promotes the Formation of Slow-Twitch Muscle Fibers through PGC-1α/miRNA but Not Mitochondria Oxidation. Journal of agricultural and food chemistry\| PubMed ID: 28654264	2017
Stearic acid suppresses mammary gland development by inhibiting PI3K/Akt signaling pathway through GPR120 in pubertal mice. Biochemical and biophysical research communications\| PubMed ID: 28712865	2017
Three-Dimensional Analysis of Chloroplast Structures Associated with Virus Infection. Plant physiology\| PubMed ID: 28821590	2018
Hijacking of the nucleolar protein fibrillarin by TGB1 is required for cell-to-cell movement of Barley stripe mosaic virus. Molecular plant pathology\| PubMed ID: 28872759	2018
Heparin Increases Food Intake through AgRP Neurons. Cell reports\| PubMed ID: 28877477	2017
α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 28939592	2018
Succinate promotes skeletal muscle protein synthesis via Erk1/2 signaling pathway. Molecular medicine reports\| PubMed ID: 28944867	2017
Construction of infectious clones of lychnis ringspot virus and evaluation of its relationship with barley stripe mosaic virus by reassortment of genomic RNA segments. Virus research\| PubMed ID: 29054449	2018
Dual-Specificity Phosphatase 12 Targets p38 MAP Kinase to Regulate Macrophage Response to Intracellular Bacterial Infection. Frontiers in immunology\| PubMed ID: 29062315	2017
Barley Stripe Mosaic Virus γb Interacts with Glycolate Oxidase and Inhibits Peroxisomal ROS Production to Facilitate Virus Infection. Molecular plant\| PubMed ID: 29066357	2018
Diversity effect of capsaicin on different types of skeletal muscle. Molecular and cellular biochemistry\| PubMed ID: 29159769	2018
Laminarin counteracts diet-induced obesity associated with glucagon-like peptide-1 secretion. Oncotarget\| PubMed ID: 29245916	2017
A novel two-component system modulates quorum sensing and pathogenicity in Burkholderia cenocepacia. Molecular microbiology\| PubMed ID: 29363827	2018
Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Plant Virus Replication. Frontiers in plant science\| PubMed ID: 29441085	2018
Barley stripe mosaic virus infection requires PKA-mediated phosphorylation of γb for suppression of both RNA silencing and the host cell death response. The New phytologist\| PubMed ID: 29453938	2018
Hsc70-2 is required for Beet black scorch virus infection through interaction with replication and capsid proteins. Scientific reports\| PubMed ID: 29540800	2018
γb Protein Subverts Autophagy to Promote Viral Infection by Disrupting the ATG7-ATG8 Interaction. The Plant cell\| PubMed ID: 29848767	2018
Age-Related Changes in MicroRNA in the Rat Pituitary and Potential Role in GH Regulation. International journal of molecular sciences\| PubMed ID: 30011963	2018
The effect of dietary ginseng polysaccharide supplementation on porcine milk-derived esRNAs involved in the host immune responses. Journal of animal physiology and animal nutrition\| PubMed ID: 30407669	2019
MiR-125b-2 Knockout in Testis Is Associated with Targeting to the PAP Gene, Mitochondrial Copy Number, and Impaired Sperm Quality. International journal of molecular sciences\| PubMed ID: 30609807	2019
Interaction between Brassica yellows virus silencing suppressor P0 and plant SKP1 facilitates stability of P0 in vivo against degradation by proteasome and autophagy pathways. The New phytologist\| PubMed ID: 30664234	2019
Disruption of Quorum Sensing and Virulence in by a Structural Analogue of the -2-Dodecenoic Acid Signal. Applied and environmental microbiology\| PubMed ID: 30770405	2019
The beneficial effects of leaf on reproductive performance in mice. Food science & nutrition\| PubMed ID: 30847152	2019
A barley stripe mosaic virus-based guide RNA delivery system for targeted mutagenesis in wheat and maize. Molecular plant pathology\| PubMed ID: 31273916	2019
TurboID-based proximity labeling reveals that UBR7 is a regulator of N NLR immune receptor-mediated immunity. Nature communications\| PubMed ID: 31324801	2019
Oral supplementation with ginseng polysaccharide promotes food intake in mice. Brain and behavior\| PubMed ID: 31392839	2019
Construction of an Infectious cDNA Clone and Comparisons of Hordeivirus Cytopathology and Pathogenicity. Phytopathology\| PubMed ID: 31483225	2020
Lower methionine/cystine ratio in low-protein diet improves animal reproductive performance by modulating methionine cycle. Food science & nutrition\| PubMed ID: 31572580	2019
Hepatic exosome-derived miR-130a-3p attenuates glucose intolerance via suppressing PHLPP2 gene in adipocyte. Metabolism: clinical and experimental\| PubMed ID: 31715176	2020
Genomewide analysis of circular RNA in pituitaries of normal and heat-stressed sows. BMC genomics\| PubMed ID: 31870281	2019
Exploration of targets regulated by miR-125b in porcine adipocytes. In vitro cellular & developmental biology. Animal\| PubMed ID: 31912457	2020
Dietary thymol supplementation promotes skeletal muscle fibre type switch in longissimus dorsi of finishing pigs. Journal of animal physiology and animal nutrition\| PubMed ID: 31975464	2020
miR-709 inhibits GHRP6 induced GH synthesis by targeting PRKCA in pituitary. Molecular and cellular endocrinology\| PubMed ID: 32084499	2020
Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation. The EMBO journal\| PubMed ID: 32104923	2020
Emerging Roles of Heat-Induced circRNAs Related to Lactogenesis in Lactating Sows. Frontiers in genetics\| PubMed ID: 32117411	2019
Genome-Wide microRNA Profiling Using Oligonucleotide Microarray Reveals Regulatory Networks of microRNAs in During Beet Necrotic Yellow Vein Virus Infection. Viruses\| PubMed ID: 32178444	2020
MiR-130a-3p Inhibits PRL Expression and Is Associated With Heat Stress-Induced PRL Reduction. Frontiers in endocrinology\| PubMed ID: 32194503	2020
Oral Administration of Bovine and Porcine Milk Exosome Alter miRNAs Profiles in Piglet Serum. Scientific reports\| PubMed ID: 32332796	2020
Milk exosome-derived miRNAs from water buffalo are implicated in immune response and metabolism process. BMC veterinary research\| PubMed ID: 32349776	2020