Sven Lang

Medical Biochemistry and Molecular Biology, Saarland University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 17	2011

Other Publications

Article	Year
Right Portal Vein Ligation Combined With In Situ Splitting Induces Rapid Left Lateral Liver Lobe Hypertrophy Enabling 2-Staged Extended Right Hepatic Resection in Small-for-Size Settings. Annals of surgery\| PubMed ID: 22330038	2012
p16INK4a is a prognostic marker in resected ductal pancreatic cancer: an analysis of p16INK4a, p53, MDM2, an Rb. Annals of surgery\| PubMed ID: 11753042	2002
CDKN2A germline mutations in familial pancreatic cancer. Annals of surgery\| PubMed ID: 12454511	2002
No contribution of multipotent mesenchymal stromal cells to liver regeneration in a rat model of prolonged hepatic injury. Stem cells (Dayton, Ohio)\| PubMed ID: 17110617	2007
Sirolimus promotes tolerance for donor and recipient antigens after MHC class II disparate bone marrow transplantation in rats. Experimental hematology\| PubMed ID: 17198885	2007
Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model. International journal of cancer. Journal international du cancer\| PubMed ID: 17230506	2007
Mycophenolate mofetil inhibits tumor growth and angiogenesis in vitro but has variable antitumor effects in vivo, possibly related to bioavailability. Transplantation\| PubMed ID: 17353782	2007
Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo. Molecular cancer therapeutics\| PubMed ID: 17363505	2007
The direct effects of anti-vascular endothelial growth factor therapy on tumor cells. Clinical colorectal cancer\| PubMed ID: 17681102	2007
Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hyp... Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17975158	2007
Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors i... Molecular cancer therapeutics\| PubMed ID: 18025273	2007
Dual inhibition of Raf and VEGFR2 reduces growth and vascularization of hepatocellular carcinoma in an experimental model. Langenbeck's archives of surgery / Deutsche Gesellschaft fÃ¼r Chirurgie\| PubMed ID: 18297306	2008
Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 18445520	2008
ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo. BMC cancer\| PubMed ID: 18651980	2008
Dual targeting of Raf and VEGF receptor 2 reduces growth and metastasis of pancreatic cancer through direct effects on tumor cells, endothelial cells, and pericytes. Molecular cancer therapeutics\| PubMed ID: 19001434	2008
Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice. Hepatology (Baltimore, Md.)\| PubMed ID: 19085954	2009
Heat-shock protein 90 (Hsp90) as a molecular target for therapy of gastrointestinal cancer. Anticancer research\| PubMed ID: 19528462	2009
Lanthanum ions inhibit the mammalian Sec61 complex in its channel dynamics and protein transport activity. FEBS letters\| PubMed ID: 19555690	2009
Up-regulation of KrÃ¼ppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha. Molecular cancer research : MCR\| PubMed ID: 19671674	2009
Results of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from colorectal cancer. Journal of surgical oncology\| PubMed ID: 19697436	2009
Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models. Surgery\| PubMed ID: 20015528	2010
Implication of RICTOR in the mTOR inhibitor-mediated induction of insulin-like growth factor-I receptor (IGF-IR) and human epidermal growth factor receptor-2 (Her2) expression in gastrointes... Biochimica et biophysica acta\| PubMed ID: 20116405	2010
Interaction of calmodulin with Sec61Î± limits Ca2+ leakage from the endoplasmic reticulum. The EMBO journal\| PubMed ID: 21102557	2011
Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition. BMC cancer\| PubMed ID: 21129190	2010
Sec62 protein level is crucial for the ER stress tolerance of prostate cancer. The Prostate\| PubMed ID: 21229553	2011
Transforming growth factor-beta 2 gene silencing with trabedersen (AP 12009) in pancreatic cancer. Cancer science\| PubMed ID: 21366804	2011
Sec61 complexes form ubiquitous ER Ca2+ leak channels. Channels (Austin, Tex.)\| PubMed ID: 21406962	2011
Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages. The Journal of clinical investigation\| PubMed ID: 21519141	2011
Sec62 protein level is crucial for the ER stress tolerance of prostate cancer. The Prostate\| PubMed ID: 21557272	2011
Targeting FGFR/PDGFR/VEGFR impairs tumor growth, angiogenesis, and metastasis by effects on tumor cells, endothelial cells, and pericytes in pancreatic cancer. Molecular cancer therapeutics\| PubMed ID: 21885862	2011
Oncogenic MST1R Activity in Pancreatic and Gastric Cancer Represents a Valid Target of HSP90 Inhibitors. Anticancer research\| PubMed ID: 22287729	2012