H. Artee Luchman

Hotchkiss Brain Institute, University of Calgary

Affiliated withUniversity of Calgary

Research Area

Cancer Research

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2018

Other Publications

Article	Year
Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium. Oncogene\| PubMed ID: 12370835	2002
Mutational-reporter transgenes rescued from mice lacking either Mgmt, or both Mgmt and Msh6 suggest that O6-alkylguanine-induced miscoding does not contribute to the spontaneous mutational s... Oncogene\| PubMed ID: 15208683	2004
Mgmt deficiency alters the in vivo mutational spectrum of tissues exposed to the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Carcinogenesis\| PubMed ID: 18281247	2008
Temporally controlled prostate epithelium-specific gene alterations. Genesis (New York, N.Y. : 2000)\| PubMed ID: 18395839	2008
The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision. PloS one\| PubMed ID: 19081794	2008
An in vivo patient-derived model of endogenous IDH1-mutant glioma. Neuro-oncology\| PubMed ID: 22166263	2012
DNA hypermethylation and 1p Loss silence NHE-1 in oligodendroglioma. Annals of neurology\| PubMed ID: 22718548	2012
On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells. Neuro-oncology\| PubMed ID: 23262510	2013
Spontaneous loss of heterozygosity leading to homozygous R132H in a patient-derived IDH1 mutant cell line. Neuro-oncology\| PubMed ID: 23757293	2013
Prostate epithelium-specific deletion of the selenocysteine tRNA gene Trsp leads to early onset intraepithelial neoplasia. The American journal of pathology\| PubMed ID: 24447801	2014
Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma. ACS medicinal chemistry letters\| PubMed ID: 24900612	2013
Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 25078279	2014
Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 25316808	2014
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism. Cancer research\| PubMed ID: 26045167	2015
Precursor States of Brain Tumor Initiating Cell Lines Are Predictive of Survival in Xenografts and Associated with Glioblastoma Subtypes. Stem cell reports\| PubMed ID: 26095605	2015
Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors. Neuro-oncology\| PubMed ID: 26245525	2016
Control of glioblastoma tumorigenesis by feed-forward cytokine signaling. Nature neuroscience\| PubMed ID: 27110918	2016
Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant . Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28916733	2017