Paul Walther

Central Facility for Electron Microscopy, Ulm University

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 13	2018
Publication title	2025

Other Publications

Article	Year
DM-GRASP/ALCAM/CD166 is required for cardiac morphogenesis and maintenance of cardiac identity in first heart field derived cells. Developmental biology\| PubMed ID: 18598690	2008
High-resolution cryo-SEM allows direct identification of F-actin at the inner nuclear membrane of Xenopus oocytes by virtue of its structural features. Journal of microscopy\| PubMed ID: 19017237	2008
The effect of carboxydextran-coated superparamagnetic iron oxide nanoparticles on c-Jun N-terminal kinase-mediated apoptosis in human macrophages. Biomaterials\| PubMed ID: 20381862	2010
Optimization of STEM tomography acquisition--a comparison of convergent beam and parallel beam STEM tomography. Ultramicroscopy\| PubMed ID: 20570046	2010
Novel electron tomographic methods to study the morphology of keratin filament networks. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada\| PubMed ID: 20598205	2010
Viral infection of cells in culture--approaches for electron microscopy. Methods in cell biology\| PubMed ID: 20869540	2010
Preparation of cryofixed cells for improved 3D ultrastructure with scanning transmission electron tomography. Histochemistry and cell biology\| PubMed ID: 21113611	2011
The tegument protein UL71 of human cytomegalovirus is involved in late envelopment and affects multivesicular bodies. Journal of virology\| PubMed ID: 21289123	2011
Protein pUL128 of human cytomegalovirus is necessary for monocyte infection and blocking of migration. Journal of virology\| PubMed ID: 21367908	2011
Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Cell host & microbe\| PubMed ID: 22177559	2011
Sho1p connects the plasma membrane with proteins of the cytokinesis network through multiple isomeric interaction states. Journal of cell science\| PubMed ID: 22623719	2012
Decellularized cartilage matrix as a novel biomatrix for cartilage tissue-engineering applications. Tissue engineering. Part A\| PubMed ID: 22690787	2012
Nuclear factor κB activation impairs ependymal ciliogenesis and links neuroinflammation to hydrocephalus formation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22915098	2012
FIB/SEM tomography with TEM-like resolution for 3D imaging of high-pressure frozen cells. Histochemistry and cell biology\| PubMed ID: 22918510	2012
High-pressure freezing for scanning transmission electron tomography analysis of cellular organelles. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23027022	2013
Human cytomegalovirus infection of M1 and M2 macrophages triggers inflammation and autologous T-cell proliferation. Journal of virology\| PubMed ID: 23055571	2013
Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication. PLoS pathogens\| PubMed ID: 23236278	2012
Freeze fracture approach to directly visualize wetting transitions on nanopatterned superhydrophobic silicon surfaces: more than a proof of principle. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 23259773	2013
Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses. Nature nanotechnology\| PubMed ID: 23334171	2013
Analysis of nuclear actin by overexpression of wild-type and actin mutant proteins. Histochemistry and cell biology\| PubMed ID: 24091797	2014
Three-dimensional imaging of adherent cells using FIB/SEM and STEM. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24357382	2014
Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Nature communications\| PubMed ID: 24691351	2014
Hepcidin knockout mice fed with iron-rich diet develop chronic liver injury and liver fibrosis due to lysosomal iron overload. Journal of hepatology\| PubMed ID: 24816174	2014
Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration. Human molecular genetics\| PubMed ID: 25552654	2015
Liposomal delivery of lipoarabinomannan triggers Mycobacterium tuberculosis specific T-cells. Tuberculosis (Edinburgh, Scotland)\| PubMed ID: 26043674	2015
3D Analysis of HCMV Induced-Nuclear Membrane Structures by FIB/SEM Tomography: Insight into an Unprecedented Membrane Morphology. Viruses\| PubMed ID: 26556360	2015
A new role for an old drug: Ambroxol triggers lysosomal exocytosis via pH-dependent Ca²⁺ release from acidic Ca²⁺ stores. Cell calcium\| PubMed ID: 26560688	2015
TDP-43 is intercellularly transmitted across axon terminals. The Journal of cell biology\| PubMed ID: 26598621	2015
Megapinocytosis: a novel endocytic pathway. Histochemistry and cell biology\| PubMed ID: 26733077	2016
Branching of keratin intermediate filaments. Journal of structural biology\| PubMed ID: 27039023	2016
Electron tomography reveals the fibril structure and lipid interactions in amyloid deposits. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27140609	2016
A small key unlocks a heavy door: The essential function of the small hydrophobic proteins SP-B and SP-C to trigger adsorption of pulmonary surfactant lamellar bodies. Biochimica et biophysica acta\| PubMed ID: 27155084	2016
Active multi-point microrheology of cytoskeletal networks. Beilstein journal of nanotechnology\| PubMed ID: 27335739	2016
Fluorescent Nanodiamond-Gold Hybrid Particles for Multimodal Optical and Electron Microscopy Cellular Imaging. Nano letters\| PubMed ID: 27629492	2016
Importance of Highly Conserved Peptide Sites of Human Cytomegalovirus gO for Formation of the gH/gL/gO Complex. Journal of virology\| PubMed ID: 27795411	2017
Metabolic Characterization of Intact Cells Reveals Intracellular Amyloid Beta but Not Its Precursor Protein to Reduce Mitochondrial Respiration. PloS one\| PubMed ID: 28005987	2016
A Luciferase Gene Driven by an Alphaherpesviral Promoter Also Responds to Immediate Early Antigens of the Betaherpesvirus HCMV, Allowing Comparative Analyses of Different Human Herpesviruses... PloS one\| PubMed ID: 28060895	2017
Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration. Molecular neurodegeneration\| PubMed ID: 28193238	2017
Amyloid plaque structure and cell surface interactions of β-amyloid fibrils revealed by electron tomography. Scientific reports\| PubMed ID: 28240273	2017
Generation and Characterization of Virus-Enhancing Peptide Nanofibrils Functionalized with Fluorescent Labels. Bioconjugate chemistry\| PubMed ID: 28300392	2017
Evaluation of methods for pore generation and their influence on physio-chemical properties of a protein based hydrogel. Biotechnology reports (Amsterdam, Netherlands)\| PubMed ID: 28352549	2016
Cell-to-cell transfer of SAA1 protein in a cell culture model of systemic AA amyloidosis. Scientific reports\| PubMed ID: 28361953	2017
Frizzled 3 acts upstream of Alcam during embryonic eye development. Developmental biology\| PubMed ID: 28427856	2017
Vaccinia virus A11 is required for membrane rupture and viral membrane assembly. Cellular microbiology\| PubMed ID: 28618160	2017
Cellular mechanism of fibril formation from serum amyloid A1 protein. EMBO reports\| PubMed ID: 28637682	2017
The cell polarity proteins Boi1p and Boi2p stimulate vesicle fusion at the plasma membrane of yeast cells. Journal of cell science\| PubMed ID: 28751498	2017
The armadillo protein p0071 controls KIF3 motor transport. Journal of cell science\| PubMed ID: 28808088	2017
LC3-associated phagocytosis in microbial pathogenesis. International journal of medical microbiology : IJMM\| PubMed ID: 29169848	2017
Laser surface modification of decellularized extracellular cartilage matrix for cartilage tissue engineering. Lasers in medical science\| PubMed ID: 29209868	2018
CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency. Human molecular genetics\| PubMed ID: 29315381	2018
sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca homeostasis and CREB1-signaling. Experimental neurology\| PubMed ID: 29466703	2018
Endonuclease G promotes mitochondrial genome cleavage and replication. Oncotarget\| PubMed ID: 29719607	2018
Opal-like Multicolor Appearance of Self-Assembled Photonic Array. ACS applied materials & interfaces\| PubMed ID: 29842782	2018
Correction: Endonuclease G promotes mitochondrial genome cleavage and replication. Oncotarget\| PubMed ID: 29963248	2018
Nutrient limitation affects presynaptic structures through dissociable Bassoon autophagic degradation and impaired vesicle release. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 29972341	2018
Investigation of modified nanopore arrays using FIB/SEM tomography. Faraday discussions\| PubMed ID: 29974089	2018
STEM tomography of high-pressure frozen and freeze-substituted cells: a comparison of image stacks obtained at 200 kV or 300 kV. Histochemistry and cell biology\| PubMed ID: 30229291	2018
Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure. The Journal of clinical investigation\| PubMed ID: 30320600	2018
Resting cells rely on the DNA helicase component MCM2 to build cilia. Nucleic acids research\| PubMed ID: 30329080	2019
Investigating HCMV entry into host cells by STEM tomography. Journal of structural biology\| PubMed ID: 30352275	2018
Detection of herpesvirus capsids in transmission electron microscopy images using transfer learning. Histochemistry and cell biology\| PubMed ID: 30488339	2019
Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation. Circulation\| PubMed ID: 30586717	2019
Regulation of Human Cytomegalovirus Secondary Envelopment by a C-Terminal Tetralysine Motif in pUL71. Journal of virology\| PubMed ID: 30996102	2019
Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. The Journal of clinical investigation\| PubMed ID: 31094706	2019
Indirect visualization of endogenous nuclear actin by correlative light and electron microscopy (CLEM) using an actin-directed chromobody. Histochemistry and cell biology\| PubMed ID: 31154480	2019
Loss of Peter Pan (PPAN) Affects Mitochondrial Homeostasis and Autophagic Flux. Cells\| PubMed ID: 31416196	2019
High porosity with tiny pore constrictions and unbending pathways characterize the 3D structure of intervessel pit membranes in angiosperm xylem. Plant, cell & environment\| PubMed ID: 31595539	2020
mir-124-5p Regulates Phagocytosis of Human Macrophages by Targeting the Actin Cytoskeleton via the ARP2/3 Complex. Frontiers in immunology\| PubMed ID: 31636629	2019
In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8-16-mer Oligomer Species. Cell reports\| PubMed ID: 31775051	2019
A Cerberus-Inspired Anti-Infective Multicomponent Gatekeeper Hydrogel against Infections with the Emerging "Superbug" Yeast Candida auris. Macromolecular bioscience\| PubMed ID: 32104975	2020
Megapinosome: Morphological description of a novel organelle. Journal of structural biology\| PubMed ID: 32247049	2020
A Placenta Derived C-Terminal Fragment of β-Hemoglobin With Combined Antibacterial and Antiviral Activity. Frontiers in microbiology\| PubMed ID: 32328038	2020
Protein Kinase D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From Cancer Cells That Promote Metastasis to Lung in Mice. Gastroenterology\| PubMed ID: 32446697	2020
The Putative Type III Secreted Virulence-Associated Protein CAB063 Targets Lamin and Induces Apoptosis. Frontiers in microbiology\| PubMed ID: 32523581	2020
Dual-axis STEM tomography at 200 kV: Setup, performance, limitations. Journal of structural biology\| PubMed ID: 32589927	2020
Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers. Journal of the American Chemical Society\| PubMed ID: 32926779	2020
Haploinsufficiency of TANK-binding kinase 1 prepones age-associated neuroinflammatory changes without causing motor neuron degeneration in aged mice. Brain communications\| PubMed ID: 33005894	2020
Improved automatic detection of herpesvirus secondary envelopment stages in electron microscopy by augmenting training data with synthetic labelled images generated by a generative adversari... Cellular microbiology\| PubMed ID: 33073426	2021
Respiratory ß-2-Microglobulin exerts pH dependent antimicrobial activity. Virulence\| PubMed ID: 33092477	2020
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas. Nature metabolism\| PubMed ID: 33536639	2021
Quantitative Electron Microscopy to Study HCMV Morphogenesis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 33555592	2021
Delivery by Dendritic Mesoporous Silica Nanoparticles Enhances the Antimicrobial Activity of a Napsin-Derived Peptide Against Intracellular Mycobacterium tuberculosis. Advanced healthcare materials\| PubMed ID: 34142469	2021
Gran1: A Granulysin-Derived Peptide with Potent Activity against Intracellular . International journal of molecular sciences\| PubMed ID: 34445098	2021
Zika virus replication in glioblastoma cells: electron microscopic tomography shows 3D arrangement of endoplasmic reticulum, replication organelles, and viral ribonucleoproteins. Histochemistry and cell biology\| PubMed ID: 34514517	2021
The Molecular Tweezer CLR01 Inhibits Antibody-Resistant Cell-to-Cell Spread of Human Cytomegalovirus. Viruses\| PubMed ID: 34578265	2021
Role of mutations and post-translational modifications in systemic AL amyloidosis studied by cryo-EM. Nature communications\| PubMed ID: 34741031	2021
Angicin, a novel bacteriocin of Streptococcus anginosus. Scientific reports\| PubMed ID: 34934110	2021
Core-Shell Imprinted Particles for Adenovirus Binding. Materials (Basel, Switzerland)\| PubMed ID: 34947287	2021
Fluorescence lifetime imaging and electron microscopy: a correlative approach. Histochemistry and cell biology\| PubMed ID: 35267057	2022
Dual signaling via interferon and DNA damage response elicits entrapment by giant PML nuclear bodies. eLife\| PubMed ID: 35319461	2022
Cas1 and Fen1 Display Equivalent Functions During Archaeal DNA Repair. Frontiers in microbiology\| PubMed ID: 35495653	2022
Clearing Chlamydia abortus infection in epithelial cells and primary human macrophages by use of antibiotics and the MDM2-p53-inhibitor nutlin-3. Diagnostic microbiology and infectious disease\| PubMed ID: 35598409	2022
Megapinosomes and homologous structures in hematopoietic cells. Histochemistry and cell biology\| PubMed ID: 35829814	2022
Vaccinia virus H7-protein is required for the organization of the viral scaffold protein into hexamers. Scientific reports\| PubMed ID: 35906465	2022
Weighted average ensemble-based semantic segmentation in biological electron microscopy images. Histochemistry and cell biology\| PubMed ID: 35988009	2022
Scalable and Tunable Diamond Nanostructuring Process for Nanoscale NMR Applications. ACS omega\| PubMed ID: 36092615	2022
An efficient capture strategy for the purification of human adenovirus type 5 from cell lysates. Journal of biotechnology\| PubMed ID: 36494010	2023
NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss. Molecular neurodegeneration\| PubMed ID: 37069623	2023
The C-terminal 32-mer fragment of hemoglobin alpha is an amyloidogenic peptide with antimicrobial properties. Cellular and molecular life sciences : CMLS\| PubMed ID: 37198527	2023
ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling. Nature communications\| PubMed ID: 37914730	2023
Functional and Morphological Differences of Muscle Mitochondria in Chronic Fatigue Syndrome and Post-COVID Syndrome. International journal of molecular sciences\| PubMed ID: 38338957	2024
Antibacterial Action of Zn Ions Driven by the In Vivo Formed ZnO Nanoparticles. ACS applied materials & interfaces\| PubMed ID: 38853353	2024
Venetoclax resistance in acute lymphoblastic leukemia is characterized by increased mitochondrial activity and can be overcome by co-targeting oxidative phosphorylation. Cell death & disease\| PubMed ID: 38961053	2024
Attenuated replication and damaging effects of SARS-CoV-2 Omicron variants in an intestinal epithelial barrier model. Journal of medical virology\| PubMed ID: 38965890	2024
Lactate-mediated mixotrophic co-cultivation of Clostridium drakei and recombinant Acetobacterium woodii for autotrophic production of volatile fatty acids. Microbial cell factories\| PubMed ID: 39061103	2024
Impact of Coenzyme Q on Mitochondrial Metabolism: A Complementary Study Using Fluorescence Lifetime Imaging and Electron Microscopy. Frontiers in bioscience (Landmark edition)\| PubMed ID: 39614446	2024
Transduction enhancing EF-C peptide nanofibrils are endocytosed by macropinocytosis and subsequently degraded. Biomaterials\| PubMed ID: 39754968	2025
α-Synuclein fibrils enhance HIV-1 infection of human T cells, macrophages and microglia. Nature communications\| PubMed ID: 39827271	2025
High-pressure freezing of mechanically stretched cells. Journal of microscopy\| PubMed ID: 40170659	2025
Provirus deletion from affects motility, stress resistance, and CRISPR RNA expression. microLife\| PubMed ID: 40395997	2025