David Lovinger

Section on Synaptic Pharmacology/Laboratory for Integrative Neuroscience, National Institutes of Health/National Institute on Alcohol Abuse and Alcoholism

Affiliated withNational Institutes of Health/National Institute on Alcohol Abuse and Alcoholism

Research Area

Neuroscience

Biography

David Lovinger has not added Biography.
If you are David Lovinger and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 17	2011

Other Publications

Article	Year
Nicotinic acetylcholine receptors interact with dopamine in induction of striatal long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11923419	2002
Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene. Hippocampus\| PubMed ID: 12000122	2002
Dicinnamoylquinides in roasted coffee inhibit the human adenosine transporter. European journal of pharmacology\| PubMed ID: 12065074	2002
NMDA receptors lose their inhibitions. Nature neuroscience\| PubMed ID: 12085089	2002
It could be habit forming: drugs of abuse and striatal synaptic plasticity. Trends in neurosciences\| PubMed ID: 12689769	2003
Phorbol ester uncouples adenosine inhibition of presynaptic Ca2+ transients at hippocampal synapses. Hippocampus\| PubMed ID: 12722976	2003
A mutation in transmembrane domain II of the 5-hydroxytryptamine(3A) receptor stabilizes channel opening and alters alcohol modulatory actions. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 12730353	2003
Ethanol inhibits alpha-amino-3-hydyroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor function in central nervous system neurons by stabilizing desensitization. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 12734392	2003
G protein-coupled endothelial receptor for atypical cannabinoid ligands modulates a Ca2+-dependent K+ current. The Journal of biological chemistry\| PubMed ID: 12952947	2003
Emerging roles for endocannabinoids in long-term synaptic plasticity. British journal of pharmacology\| PubMed ID: 14504143	2003
A predominant role for inhibition of the adenylate cyclase/protein kinase A pathway in ERK activation by cannabinoid receptor 1 in N1E-115 neuroblastoma cells. The Journal of biological chemistry\| PubMed ID: 14517212	2003
Plastic control of striatal glutamatergic transmission by ensemble actions of several neurotransmitters and targets for drugs of abuse. Annals of the New York Academy of Sciences\| PubMed ID: 14684449	2003
Disruption of endocannabinoid release and striatal long-term depression by postsynaptic blockade of endocannabinoid membrane transport. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14973237	2004
Serotonin-3 receptors in the actions of alcohol, alcohol reinforcement, and alcoholism. Alcoholism, clinical and experimental research\| PubMed ID: 15112933	2004
Cortical neurons lacking KCC2 expression show impaired regulation of intracellular chloride. Journal of neurophysiology\| PubMed ID: 15469961	2005
Induction of striatal long-term synaptic depression by moderate frequency activation of cortical afferents in rat. The Journal of physiology\| PubMed ID: 15498813	2005
Maturation of cultured hippocampal slices results in increased excitability in granule cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience\| PubMed ID: 15730888	2005
CaMKIIalpha 的自磷酸化依赖机制增强了 NR2B 含 NMDA 受体的脱敏。 Molecular and cellular neurosciences\| PubMed ID: 15866054	2005
Retrograde endocannabinoid signaling in a postsynaptic neuron/synaptic bouton preparation from basolateral amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15987949	2005
Role of aspartate 298 in mouse 5-HT3A receptor gating and modulation by extracellular Ca2+. The Journal of physiology\| PubMed ID: 16096341	2005
Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16162920	2005
Laboratory models of alcoholism: treatment target identification and insight into mechanisms. Nature neuroscience\| PubMed ID: 16251990	2005
Actions of acute and chronic ethanol on presynaptic terminals. Alcoholism, clinical and experimental research\| PubMed ID: 16441271	2006
Effects of ethanol on adenosine 5'-triphosphate-gated purinergic and 5-hydroxytryptamine receptors. Alcoholism, clinical and experimental research\| PubMed ID: 16441284	2006
Mutations of L293 in transmembrane two of the mouse 5-hydroxytryptamine3A receptor alter gating and alcohol modulatory actions. British journal of pharmacology\| PubMed ID: 16520747	2006
Ethanol potentiates GABAergic synaptic transmission in a postsynaptic neuron/synaptic bouton preparation from basolateral amygdala. Journal of neurophysiology\| PubMed ID: 16624993	2006
Temperature: an important experimental variable in studying PKC modulation of ligand-gated ion channels. Brain research\| PubMed ID: 16626662	2006
Dopaminergic control of corticostriatal long-term synaptic depression in medium spiny neurons is mediated by cholinergic interneurons. Neuron\| PubMed ID: 16675398	2006
Frequency-specific and D2 receptor-mediated inhibition of glutamate release by retrograde endocannabinoid signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16698932	2006
Ethanol effects on electrophysiological properties of astrocytes in striatal brain slices. Neuropharmacology\| PubMed ID: 16938316	2006
Ethanol inhibits brain-derived neurotrophic factor stimulation of extracellular signal-regulated/mitogen-activated protein kinase in cerebellar granule cells. Alcohol (Fayetteville, N.Y.)\| PubMed ID: 16938627	2006
Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17015831	2006
The role of protein synthesis in striatal long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17108154	2006
Mixing proteomics and alcohol. Alcohol (Fayetteville, N.Y.)\| PubMed ID: 17157715	2006
Anandamide regulates postnatal development of long-term synaptic plasticity in the rat dorsolateral striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17329438	2007
Persistent synaptic activity produces long-lasting enhancement of endocannabinoid modulation and alters long-term synaptic plasticity. Journal of neurophysiology\| PubMed ID: 17392410	2007
Ethanol induces long-term facilitation of NR2B-NMDA receptor activity in the dorsal striatum: implications for alcohol drinking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17392475	2007
Tonic for what ails us? high-affinity GABAA receptors and alcohol. Alcohol (Fayetteville, N.Y.)\| PubMed ID: 17521844	2007
Ethanol reverses the direction of long-term synaptic plasticity in the dorsomedial striatum. The European journal of neuroscience\| PubMed ID: 17552991	2007
Combined activation of L-type Ca2+ channels and synaptic transmission is sufficient to induce striatal long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17581965	2007
Neurotensin reduces glutamatergic transmission in the dorsolateral striatum via retrograde endocannabinoid signaling. Neuropharmacology\| PubMed ID: 17675102	2008
Endocannabinoid liberation from neurons in transsynaptic signaling. Journal of molecular neuroscience : MN\| PubMed ID: 17901551	2007
Medication discrepancies in resident sign-outs and their potential to harm. Journal of general internal medicine\| PubMed ID: 17963009	2007
Presynaptic modulation by endocannabinoids. Handbook of experimental pharmacology\| PubMed ID: 18064422	2008
Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18077376	2007
Electrophysiological properties and gap junction coupling of striatal astrocytes. Neurochemistry international\| PubMed ID: 18396351	2008
The L293 residue in transmembrane domain 2 of the 5-HT3A receptor is a molecular determinant of allosteric modulation by 5-hydroxyindole. Neuropharmacology\| PubMed ID: 18436267	2008
Endocannabinoid- and mGluR5-dependent short-term synaptic depression in an isolated neuron/bouton preparation from the hippocampal CA1 region. Journal of neurophysiology\| PubMed ID: 18497350	2008
The endogenous brain constituent N-arachidonoyl L-serine is an activator of large conductance Ca2+-activated K+ channels. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 18923087	2009
Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity. The European journal of neuroscience\| PubMed ID: 19120438	2009
Frequency-dependent inversion of net striatal output by endocannabinoid-dependent plasticity at different synaptic inputs. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19193884	2009
Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill. Nature neuroscience\| PubMed ID: 19198605	2009
Acute alcohol action and desensitization of ligand-gated ion channels. Pharmacological reviews\| PubMed ID: 19270242	2009
Ethanol increases desensitization of recombinant GluR-D AMPA receptor and TARP combinations. Alcohol (Fayetteville, N.Y.)\| PubMed ID: 19560629	2009
Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function. Journal of neurochemistry\| PubMed ID: 19682204	2009
Hydrophobic photolabeling studies identify the lipid-protein interface of the 5-HT3A receptor. Biochemistry\| PubMed ID: 19715355	2009
Developmental alteration of endocannabinoid retrograde signaling in the hippocampus. Journal of neurophysiology\| PubMed ID: 20007500	2010
Neurotransmitter roles in synaptic modulation, plasticity and learning in the dorsal striatum. Neuropharmacology\| PubMed ID: 20096294	2010
Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20357110	2010
International Review of Neurobiology. Functional plasticity and genetic variation: insights into the neurobiology of alcoholism. Preface. International review of neurobiology\| PubMed ID: 20813237	2010
Endocannabinoids rein in pain outside the brain. Nature neuroscience\| PubMed ID: 20877276	2010
N-Docosahexaenoylethanolamide promotes development of hippocampal neurons. The Biochemical journal\| PubMed ID: 21281269	2011
Fluorophore assisted light inactivation (FALI) of recombinant 5-HTâ‚ƒA receptor constitutive internalization and function. Molecular and cellular neurosciences\| PubMed ID: 21338684	2011
Serotonin induces long-term depression at corticostriatal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21593324	2011
Striatal involvement in human alcoholism and alcohol consumption, and withdrawal in animal models. Alcoholism, clinical and experimental research\| PubMed ID: 21615425	2011
Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors. Nature neuroscience\| PubMed ID: 21743470	2011
Synaptic Effects Induced by Alcohol. Current topics in behavioral neurosciences\| PubMed ID: 21786203	2011
Synaptic and morphological neuroadaptations in the putamen associated with long-term, relapsing alcohol drinking in primates. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 21796110	2011
Organophosphates dysregulate dopamine signaling, glutamatergic neurotransmission, and induce neuronal injury markers in striatum. Journal of neurochemistry\| PubMed ID: 21848865	2011
An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 Î”GAG knock-in mice. Behavioural brain research\| PubMed ID: 21995941	2012
Characterization of Two Mutations, M287L and Q266I, in the Î±1 Glycine Receptor Subunit That Modify Sensitivity to Alcohols. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 22037201	2012
Subsets of Spiny Striosomal Striatal Neurons Revealed in the Gad1-GFP BAC Transgenic Mouse. Basal ganglia\| PubMed ID: 22140656	2011
Serotonergic action on dorsal striatal function. Parkinsonism & related disorders\| PubMed ID: 22166410	2012
Endocannabinoids in striatal plasticity. Parkinsonism & related disorders\| PubMed ID: 22166411	2012