Stuart C. Sealfon

Center for Translational Systems Biology and Department of Neurology, Mount Sinai School of Medicine

Affiliated withMount Sinai School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2011

Other Publications

Article	Year
Strategies for mapping the binding site of the serotonin 5-HT2A receptor. Methods in enzymology\| PubMed ID: 11665561	2002
Monitoring G-protein-coupled receptor signaling with DNA microarrays and real-time polymerase chain reaction. Methods in enzymology\| PubMed ID: 11665639	2002
Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays. Nucleic acids research\| PubMed ID: 12000853	2002
Coupling of GnRH concentration and the GnRH receptor-activated gene program. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 12040003	2002
Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations. The Journal of biological chemistry\| PubMed ID: 12145300	2002
Validated genomic approach to study differentially expressed genes in complex tissues. Neurochemical research\| PubMed ID: 12462402	2002
Molecular basis of partial agonism: orientation of indoleamine ligands in the binding pocket of the human serotonin 5-HT2A receptor determines relative efficacy. Molecular pharmacology\| PubMed ID: 12488534	2003
Activation of phosphoinositide 3-kinase by D2 receptor prevents apoptosis in dopaminergic cell lines. The Biochemical journal\| PubMed ID: 12683952	2003
Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor. The Journal of biological chemistry\| PubMed ID: 12970364	2003
Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14523084	2003
Structure of the GnRH receptor-stimulated signaling network: insights from genomics. Frontiers in neuroendocrinology\| PubMed ID: 14596811	2003
Focused microarray analysis. Methods (San Diego, Calif.)\| PubMed ID: 14597315	2003
Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress. The Journal of biological chemistry\| PubMed ID: 15078887	2004
Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression. Neurochemical research\| PubMed ID: 15176466	2004
Genomics view of gonadotrope signaling circuits. Trends in endocrinology and metabolism: TEM\| PubMed ID: 15350605	2004
Mutational analysis of the serotonin receptor 5HT2c in severe early-onset human obesity. Canadian journal of physiology and pharmacology\| PubMed ID: 15381968	2004
Epsilon-sarcoglycan immunoreactivity and mRNA expression in mouse brain. The Journal of comparative neurology\| PubMed ID: 15612018	2005
CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 15774504	2005
Acute induction of gene expression in brain and liver by insulin-induced hypoglycemia. Diabetes\| PubMed ID: 15793232	2005
Teaching resources. G-protein-coupled receptors. Science's STKE : signal transduction knowledge environment\| PubMed ID: 15827322	2005
Local protein synthesis mediates a rapid increase in dendritic elongation factor 1A after induction of late long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15958750	2005
Transcript profiling of immediate early genes reveals a unique role for activating transcription factor 3 in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonado... Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 15961508	2005
Method for multiplex cellular detection of mRNAs using quantum dot fluorescent in situ hybridization. Nucleic acids research\| PubMed ID: 16224100	2005
Chronic exposure to TNF-alpha increases airway mucus gene expression in vivo. The Journal of allergy and clinical immunology\| PubMed ID: 16337454	2005
The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells. The Journal of clinical investigation\| PubMed ID: 16604194	2006
Influenza virus evades innate and adaptive immunity via the NS1 protein. Journal of virology\| PubMed ID: 16775317	2006
Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science (New York, N.Y.)\| PubMed ID: 16873667	2006
Mixed analog/digital gonadotrope biosynthetic response to gonadotropin-releasing hormone. The Journal of biological chemistry\| PubMed ID: 16916798	2006
p53 mediates nontranscriptional cell death in dopaminergic cells in response to proteasome inhibition. The Journal of biological chemistry\| PubMed ID: 17060322	2006
Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior. Neuron\| PubMed ID: 17270739	2007
Biphasic effects of postnatal exposure to diethylhexylphthalate on the timing of puberty in male rats. Journal of andrology\| PubMed ID: 17287459	2007
Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone beta subunit transcription. Journal of molecular endocrinology\| PubMed ID: 17293449	2007
BioPP: a tool for web-publication of biological networks. BMC bioinformatics\| PubMed ID: 17519033	2007
Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells. Nucleic acids research\| PubMed ID: 17675303	2007
Noise propagation and scaling in regulation of gonadotrope biosynthesis. Biophysical journal\| PubMed ID: 17720728	2007
Time and length scales of autocrine signals in three dimensions. Biophysical journal\| PubMed ID: 17720734	2007
Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature\| PubMed ID: 18297054	2008
Getting started in biological pathway construction and analysis. PLoS computational biology\| PubMed ID: 18463709	2008
Cell-to-cell communication: time and length scales of ligand internalization in cultures of suspended cells. The Journal of chemical physics\| PubMed ID: 18554059	2008
Receptor pair for schizophrenia. Pediatric research\| PubMed ID: 18574404	2008
A comprehensive evaluation of human plasmacytoid dendritic cells using small volumes of human blood. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 18729740	2008
Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus. PLoS pathogens\| PubMed ID: 18974865	2008
Antiviral-activated dendritic cells: a paracrine-induced response state. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18981106	2008
SOME STEP-DOWN PROCEDURES CONTROLLING THE FALSE DISCOVERY RATE UNDER DEPENDENCE. Statistica Sinica\| PubMed ID: 19018297	2008
Psychedelics and schizophrenia. Trends in neurosciences\| PubMed ID: 19269047	2009
Agonist-trafficking and hallucinogens. Current medicinal chemistry\| PubMed ID: 19275609	2009
Microtranscriptome regulation by gonadotropin-releasing hormone. Molecular and cellular endocrinology\| PubMed ID: 19356622	2009
Model of autocrine/paracrine signaling in epithelial layer: geometrical regulation of intercellular communication. The journal of physical chemistry. B\| PubMed ID: 19601596	2009
Group II metabotropic glutamate receptors and schizophrenia. Cellular and molecular life sciences : CMLS\| PubMed ID: 19707855	2009
Multiple testing and its applications to microarrays. Statistical methods in medical research\| PubMed ID: 20048384	2009
Immune response modeling of interferon beta-pretreated influenza virus-infected human dendritic cells. Biophysical journal\| PubMed ID: 20159146	2010
Antiviral response dictated by choreographed cascade of transcription factors. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20164420	2010
Coregulation mapping based on individual phenotypic variation in response to virus infection. Immunome research\| PubMed ID: 20298589	2010
Plato's cave algorithm: inferring functional signaling networks from early gene expression shadows. PLoS computational biology\| PubMed ID: 20585619	2010
Research resource: Gonadotropin-releasing hormone receptor-mediated signaling network in LbetaT2 cells: a pathway-based web-accessible knowledgebase. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 20592162	2010
Heteromerization of G protein-coupled receptors: relevance to neurological disorders and neurotherapeutics. CNS & neurological disorders drug targets\| PubMed ID: 20632964	2010
Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study. Journal of virology\| PubMed ID: 20739535	2010
Validation of efficient high-throughput plasmid and siRNA transfection of human monocyte-derived dendritic cells without cell maturation. Journal of immunological methods\| PubMed ID: 20875421	2010
Signaling network of dendritic cells in response to pathogens: a community-input supported knowledgebase. BMC systems biology\| PubMed ID: 20929569	2010
Misty Mountain clustering: application to fast unsupervised flow cytometry gating. BMC bioinformatics\| PubMed ID: 20932336	2010
RNA and DNA microarrays. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20967621	2011
Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists. Neuroscience letters\| PubMed ID: 21276828	2011
Role of cell-to-cell variability in activating a positive feedback antiviral response in human dendritic cells. PloS one\| PubMed ID: 21347441	2011
Differential gene expression in patients with amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases\| PubMed ID: 21375368	2011
Characterization of a MAPK scaffolding protein logic gate in gonadotropes. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 21436256	2011
Improved compensation in flow cytometry by multivariable optimization. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 21485003	2011
Functional crosstalk and heteromerization of serotonin 5-HT2A and dopamine D2 receptors. Neuropharmacology\| PubMed ID: 21645528	2011
Authors response to correspondence about an improved compensation method. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 22065546	2011
Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs. Cell\| PubMed ID: 22118459	2011
Optimized amplification and single-cell analysis identify GnRH-mediated activation of Rap1b in primary rat gonadotropes. Molecular and cellular endocrinology\| PubMed ID: 22127306	2012
Multi-scale stochastic simulation of diffusion-coupled agents and its application to cell culture simulation. PloS one\| PubMed ID: 22216238	2011