James A. Traherne

Department of Pathology, University of Cambridge

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 8	2019

Other Publications

Article	Year
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history. PLoS genetics\| PubMed ID: 16440057	2006
Splice variation in the cytoplasmic domains of myelin oligodendrocyte glycoprotein affects its cellular localisation and transport. Journal of neurochemistry\| PubMed ID: 17573820	2007
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project. Immunogenetics\| PubMed ID: 18193213	2008
Human MHC architecture and evolution: implications for disease association studies. International journal of immunogenetics\| PubMed ID: 18397301	2008
Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G. PloS one\| PubMed ID: 19223974	2009
Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex. Human molecular genetics\| PubMed ID: 19959527	2010
Genetic variation, Fcγ receptors, KIRs and infection: the evolution of autoimmunity. Current opinion in immunology\| PubMed ID: 21050737	2010
Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis. Hepatology (Baltimore, Md.)\| PubMed ID: 21413052	2011
Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors. Genome research\| PubMed ID: 22948769	2012
Killer cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population. Immunogenetics\| PubMed ID: 23974321	2013
Copy number and nucleotide variation of the LILR family of myelomonocytic cell activating and inhibitory receptors. Immunogenetics\| PubMed ID: 24257760	2014
TAPBPR isoforms exhibit altered association with MHC class I. Immunology\| PubMed ID: 24444341	2014
Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR. Genome medicine\| PubMed ID: 24597950	2014
A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples. BMC genomics\| PubMed ID: 24720548	2014
KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand. Immunogenetics\| PubMed ID: 25139336	2014
Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population. PloS one\| PubMed ID: 25521205	2014
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nature genetics\| PubMed ID: 25559196	2015
A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25561558	2015
Surveillance of cell and tissue perturbation by receptors in the LRC. Immunological reviews\| PubMed ID: 26284474	2015
Imputation of KIR Types from SNP Variation Data. American journal of human genetics\| PubMed ID: 26430804	2015
LILRA6 copy number variation correlates with susceptibility to atopic dermatitis. Immunogenetics\| PubMed ID: 27333811	2016
Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing. American journal of human genetics\| PubMed ID: 27486779	2016
qKAT: a high-throughput qPCR method for KIR gene copy number and haplotype determination. Genome medicine\| PubMed ID: 27686127	2016
Deciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology. Immunology\| PubMed ID: 27779741	2017
Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease. Nature genetics\| PubMed ID: 28067912	2017
Novel KIR genotypes and gene copy number variations in northeastern Thais. Immunology\| PubMed ID: 28950036	2018
High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 30249807	2018
Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop. Human immunology\| PubMed ID: 30321631	2018
A novel antibody combination to identify KIR2DS2 natural killer cells in KIR2DL3/L2/S2 heterozygous donors. HLA\| PubMed ID: 30381896	2019
Inhibitory killer cell immunoglobulin-like receptors strengthen CD8 T cell-mediated control of HIV-1, HCV, and HTLV-1. Science immunology\| PubMed ID: 30413420	2018