Christine L. Mummery

Department of Anatomy and Embryology, Leiden University Medical Center

Affiliated withLeiden University Medical Center University of Twente Leiden University Medical Center

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2018

Other Publications

Article	Year
SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 17195180	2007
Prospects for pluripotent stem cell-derived cardiomyocytes in cardiac cell therapy and as disease models. Journal of cellular biochemistry\| PubMed ID: 19449339	2009
Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes. Cellular and molecular life sciences : CMLS\| PubMed ID: 19844658	2010
Challenges in using stem cells for cardiac repair. Science translational medicine\| PubMed ID: 20393186	2010
Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models. The Biochemical journal\| PubMed ID: 21269276	2011
Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development. Trends in molecular medicine\| PubMed ID: 21703926	2011
Shedding new light on the mechanism underlying stem cell therapy for the heart. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 21720378	2011
Human embryonic and fetal mesenchymal stem cells differentiate toward three different cardiac lineages in contrast to their adult counterparts. PloS one\| PubMed ID: 21931658	2011
New perspectives on regeneration of the heart. Circulation research\| PubMed ID: 21960722	2011
Smooth muscle diversity from human pluripotent cells. Nature biotechnology\| PubMed ID: 22318032	2012
Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease. Circulation\| PubMed ID: 22647976	2012
Induced pluripotent stem cells: the new patient? Nature reviews. Molecular cell biology\| PubMed ID: 23034453	2012
Model systems for cardiovascular regenerative biology. Cold Spring Harbor perspectives in medicine\| PubMed ID: 23545574	2013
Is heart regeneration on the right track? Nature medicine\| PubMed ID: 23558629	2013
Conversion of mature human β-cells into glucagon-producing α-cells. Diabetes\| PubMed ID: 23569174	2013
Generation of induced pluripotent stem cells from human foetal fibroblasts using the Sleeping Beauty transposon gene delivery system. Differentiation; research in biological diversity\| PubMed ID: 23933400	2013
Direct cardiomyocyte reprogramming: a new direction for cardiovascular regenerative medicine. Cold Spring Harbor perspectives in medicine\| PubMed ID: 24003244	2013
Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 24158517	2014
Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome. The EMBO journal\| PubMed ID: 24213244	2013
PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function. Stem cell reports\| PubMed ID: 24371810	2013
Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones. Experimental cell research\| PubMed ID: 24836851	2014
Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells. Nature protocols\| PubMed ID: 24874816	2014
SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development. Stem cell research\| PubMed ID: 24968096	2014
Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes. Journal of cellular and molecular medicine\| PubMed ID: 24981391	2014
Cell replacement therapies: is it time to reprogram? Human gene therapy\| PubMed ID: 25141889	2014
Assessment of functional competence of endothelial cells from human pluripotent stem cells in zebrafish embryos. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25173378	2014
A case for crowd sourcing in stem cell research. Stem cells translational medicine\| PubMed ID: 25232185	2014
Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25453094	2014
Pluripotent stem cell derived cardiovascular progenitors--a developmental perspective. Developmental biology\| PubMed ID: 25624264	2015
Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes Under Defined Conditions. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25626427	2016
Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology. EMBO molecular medicine\| PubMed ID: 25700171	2015
Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro--correlation between contraction force and electrophysiology. Biomaterials\| PubMed ID: 25771005	2015
Lymphangiogenesis and angiogenesis during human fetal pancreas development. Vascular cell\| PubMed ID: 25785186	2014
Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25795241	2015
What Endothelial Cells from Patient iPSCs Can Tell Us about Aortic Valve Disease. Cell stem cell\| PubMed ID: 25957898	2015
The composition and differentiation potential of the duodenal intraepithelial innate lymphocyte compartment is altered in coeliac disease. Gut\| PubMed ID: 25966995	2016
KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas. Stem cell reports\| PubMed ID: 26028532	2015
Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells. Nature biotechnology\| PubMed ID: 26192318	2015
Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells. Development (Cambridge, England)\| PubMed ID: 26209647	2015
Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure. Biochemical and biophysical research communications\| PubMed ID: 26456652	2015
Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function. Cell reports\| PubMed ID: 26489474	2015
Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva. Stem cell reports\| PubMed ID: 26626181	2015
Advantages of the avian model for human ovarian cancer. Molecular and clinical oncology\| PubMed ID: 26807219	2015
Interaction Between ALK1 Signaling and Connexin40 in the Development of Arteriovenous Malformations. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26821948	2016
The avian embryo to study development of the cardiac conduction system. Differentiation; research in biological diversity\| PubMed ID: 26856662	2016
Complex Tissue and Disease Modeling using hiPSCs. Cell stem cell\| PubMed ID: 26942851	2016
Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and he... European heart journal\| PubMed ID: 27055812	2016
Stem cells: The cancer's gone, but did chemotherapy damage your heart? Nature reviews. Cardiology\| PubMed ID: 27226155	2016
Concise Review: Measuring Physiological Responses of Human Pluripotent Stem Cell Derived Cardiomyocytes to Drugs and Disease. Stem cells (Dayton, Ohio)\| PubMed ID: 27250776	2016
Inherited heart disease - what can we expect from the second decade of human iPS cell research? FEBS letters\| PubMed ID: 27391414	2016
A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells. EMBO molecular medicine\| PubMed ID: 27470144	2016
Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come? British journal of pharmacology\| PubMed ID: 27641943	2016
Readthrough-Promoting Drugs Gentamicin and PTC124 Fail to Rescue Nav1.5 Function of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying Nonsense Mutations in the Sodium Chann... Circulation. Arrhythmia and electrophysiology\| PubMed ID: 27784737	2016
Small molecule absorption by PDMS in the context of drug response bioassays. Biochemical and biophysical research communications\| PubMed ID: 27856254	2017
TECRL, a new life-threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT. EMBO molecular medicine\| PubMed ID: 27861123	2016
Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes. Biochemical and biophysical research communications\| PubMed ID: 28153730	2018
Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes. European heart journal\| PubMed ID: 28182242	2017
Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells. Development (Cambridge, England)\| PubMed ID: 28279973	2017
Differentiation-Defective Human Induced Pluripotent Stem Cells Reveal Strengths and Limitations of the Teratoma Assay and In Vitro Pluripotency Assays. Stem cell reports\| PubMed ID: 28494940	2017
FANTOM5 CAGE profiles of human and mouse samples. Scientific data\| PubMed ID: 28850106	2017
Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies. Disease models & mechanisms\| PubMed ID: 28883014	2017
DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells. Nature communications\| PubMed ID: 29030611	2017
Co-Differentiation of Human Pluripotent Stem Cells-Derived Cardiomyocytes and Endothelial Cells from Cardiac Mesoderm Provides a Three-Dimensional Model of Cardiac Microtissue. Current protocols in human genetics\| PubMed ID: 29044469	2017
Executive summary of the 12th HHT international scientific conference. Angiogenesis\| PubMed ID: 29147802	2018
A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes. Stem cell reports\| PubMed ID: 29173897	2017
Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells. Stem cell reports\| PubMed ID: 29173898	2017
MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo. Circulation research\| PubMed ID: 29282212	2018
Squaramide-Based Supramolecular Materials for Three-Dimensional Cell Culture of Human Induced Pluripotent Stem Cells and Their Derivatives. Biomacromolecules\| PubMed ID: 29528623	2018
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network. Nature communications\| PubMed ID: 29636455	2018
Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells. Stem cell reports\| PubMed ID: 29657098	2018
Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology. Advanced drug delivery reviews\| PubMed ID: 29944904	2018
Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell-Derived Cardiomyocytes to Zebrafish and Human Hearts. Current protocols in human genetics\| PubMed ID: 30253059	2018
Cytostretch, an Organ-on-Chip Platform. Micromachines\| PubMed ID: 30404293	2016