Frank Buchholz

Max Plank Institute for Molecular Cell Biology and Genetics, Dresden

Affiliated withMax Plank Institute for Molecular Cell Biology and Genetics, Dresden Max Planck Institute of Molecular Cell Biology and Genetics

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 4	2008
Publication title Cited by 17	2010

Other Publications

Article	Year
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12096193	2002
Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12391321	2002
Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation. Nucleic acids research\| PubMed ID: 12954782	2003
RNA interference: gene silencing in the fast lane. Seminars in cancer biology\| PubMed ID: 14563120	2003
Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. Journal of virology\| PubMed ID: 15016866	2004
Tissue-specific RNA interference in post-implantation mouse embryos using directional electroporation and whole embryo culture. Differentiation; research in biological diversity\| PubMed ID: 15066189	2004
DEQOR: a web-based tool for the design and quality control of siRNAs. Nucleic acids research\| PubMed ID: 15215362	2004
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division. Nature\| PubMed ID: 15616564	2004
RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15695330	2005
Functional genomic analysis of cell division by endoribonuclease-prepared siRNAs. Cell cycle (Georgetown, Tex.)\| PubMed ID: 15876870	2005
Selective expression of the Cre recombinase in late-stage thymocytes using the distal promoter of the Lck gene. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15905512	2005
Production of endoribonuclease-prepared short interfering RNAs for gene silencing in mammalian cells. Nature methods\| PubMed ID: 16179925	2005
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature\| PubMed ID: 16541024	2006
Enzymatically prepared RNAi libraries. Nature methods\| PubMed ID: 16929314	2006
Minimizing the risk of reporting false positives in large-scale RNAi screens. Nature methods\| PubMed ID: 16990807	2006
RNAi in embryonic stem cells. Stem cell reviews\| PubMed ID: 17142881	2006
RUNX1 DNA-binding mutants, associated with minimally differentiated acute myelogenous leukemia, disrupt myeloid differentiation. Cancer research\| PubMed ID: 17234761	2007
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies. Nature methods\| PubMed ID: 17351622	2007
Tandem affinity purification of functional TAP-tagged proteins from human cells. Nature protocols\| PubMed ID: 17546005	2007
HIV-1 proviral DNA excision using an evolved recombinase. Science (New York, N.Y.)\| PubMed ID: 17600219	2007
Genome-scale RNAi profiling of cell division in human tissue culture cells. Nature cell biology\| PubMed ID: 17994010	2007
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nature methods\| PubMed ID: 18391959	2008
Systems biology of mammalian cell division. Cell cycle (Georgetown, Tex.)\| PubMed ID: 18635956	2008
Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives. BMC genomics\| PubMed ID: 19203379	2009
The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1. Gastroenterology\| PubMed ID: 19328795	2009
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell stem cell\| PubMed ID: 19345177	2009
Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. The EMBO journal\| PubMed ID: 19387489	2009
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Current biology : CB\| PubMed ID: 19427217	2009
Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice. Disease models & mechanisms\| PubMed ID: 19692579	2009
Engineering DNA processing enzymes for the postgenomic era. Current opinion in biotechnology\| PubMed ID: 19700301	2009
The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation. PloS one\| PubMed ID: 19727443	2009
SKAnking with Ska3: essential role of Ska3 in cell division revealed by combined phenotypic profiling. Cell cycle (Georgetown, Tex.)\| PubMed ID: 19838048	2009
A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth. EMBO reports\| PubMed ID: 20134481	2010
Systems survey of endocytosis by multiparametric image analysis. Nature\| PubMed ID: 20190736	2010
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science (New York, N.Y.)\| PubMed ID: 20360068	2010
PhenoFam-gene set enrichment analysis through protein structural information. BMC bioinformatics\| PubMed ID: 20478033	2010
SeLOX--a locus of recombination site search tool for the detection and directed evolution of site-specific recombination systems. Nucleic acids research\| PubMed ID: 20529878	2010
In vitro evolution and analysis of HIV-1 LTR-specific recombinases. Methods (San Diego, Calif.)\| PubMed ID: 20600935	2011
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. PLoS biology\| PubMed ID: 20613862	2010
High-throughput RNAi screening in mammalian cells with esiRNAs. Methods (San Diego, Calif.)\| PubMed ID: 21185384	2011
Production of Endoribonuclease-Prepared Short Interfering RNAs (esiRNAs) for Specific and Effective Gene Silencing in Mammalian Cells. CSH protocols\| PubMed ID: 21357149	2007
From RNAi Screens to Molecular Function in Embryonic Stem Cells. Stem cell reviews\| PubMed ID: 21526416	2011
RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity. PloS one\| PubMed ID: 21589869	2011
A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly. Nature cell biology\| PubMed ID: 21642980	2011
An RNA interference phenotypic screen identifies a role for FGF signals in colon cancer progression. PloS one\| PubMed ID: 21853123	2011
Ribosome biogenesis and p53: who is regulating whom? Cell cycle (Georgetown, Tex.)\| PubMed ID: 22067651	2011
Combined RNAi and localization for functionally dissecting long noncoding RNAs. Nature methods\| PubMed ID: 22327834	2012