Akira Ainai

Department of Pathology, National Institute of Infectious Diseases

Affiliated withNational Institute of Infectious Diseases

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2019

Other Publications

Article	Year
Development of mucosal adjuvants for intranasal vaccine for H5N1 influenza viruses. Therapeutics and clinical risk management\| PubMed ID: 19436601	2009
PolyI:polyC12U adjuvant-combined intranasal vaccine protects mice against highly pathogenic H5N1 influenza virus variants. Vaccine\| PubMed ID: 19840660	2009
Induction of cross-protective immunity against influenza A virus H5N1 by an intranasal vaccine with extracts of mushroom mycelia. Journal of medical virology\| PubMed ID: 19950232	2010
The first autopsy case of pandemic influenza (A/H1N1pdm) virus infection in Japan: detection of a high copy number of the virus in type II alveolar epithelial cells by pathological and virol... Japanese journal of infectious diseases\| PubMed ID: 20093768	2010
Characterization of quasispecies of pandemic 2009 influenza A virus (A/H1N1/2009) by de novo sequencing using a next-generation DNA sequencer. PloS one\| PubMed ID: 20428231	2010
Intranasal administration of adjuvant-combined vaccine protects monkeys from challenge with the highly pathogenic influenza A H5N1 virus. Journal of medical virology\| PubMed ID: 20827774	2010
Cross-protective immunity against influenza virus infections induced by intranasal vaccination together with a TLR3-mucosal adjuvant. Human vaccines\| PubMed ID: 21321485	2011
A novel function of the N-terminal domain of PA in assembly of influenza A virus RNA polymerase. Biochemical and biophysical research communications\| PubMed ID: 22001919	2011
Outer membrane vesicles of Porphyromonas gingivalis elicit a mucosal immune response. PloS one\| PubMed ID: 22022548	2011
Characterization of neutralizing antibodies in adults after intranasal vaccination with an inactivated influenza vaccine. Journal of medical virology\| PubMed ID: 22170556	2012
Mucosal IgA responses in influenza virus infections; thoughts for vaccine design. Vaccine\| PubMed ID: 22835738	2012
The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses. Journal of virology\| PubMed ID: 24600012	2014
Combatting infectious diseases; nanotechnology as a platform for rational vaccine design. Advanced drug delivery reviews\| PubMed ID: 24862579	2014
Cytokine profile of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during seasonal H1N1 infection. Cytokine\| PubMed ID: 24998935	2014
Relationship of the quaternary structure of human secretory IgA to neutralization of influenza virus. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26056267	2015
Host Adaptation and the Alteration of Viral Properties of the First Influenza A/H1N1pdm09 Virus Isolated in Japan. PloS one\| PubMed ID: 26079133	2015
Protective antibody responses against A(H1N1)pdm09 primed by infection and recalled by intranasal vaccination. Vaccine\| PubMed ID: 26432916	2015
The effect of mucoadhesive excipient on the nasal retention time of and the antibody responses induced by an intranasal influenza vaccine. Vaccine\| PubMed ID: 26802605	2016
Intranasal Inactivated Influenza Vaccines: a Reasonable Approach to Improve the Efficacy of Influenza Vaccine? Japanese journal of infectious diseases\| PubMed ID: 27212584	2016
Impacts of allergic airway inflammation on lung pathology in a mouse model of influenza A virus infection. PloS one\| PubMed ID: 28245238	2017
Intranasal Administration of Whole Inactivated Influenza Virus Vaccine as a Promising Influenza Vaccine Candidate. Viral immunology\| PubMed ID: 28650274	2017
Functional and structural characteristics of secretory IgA antibodies elicited by mucosal vaccines against influenza virus. Vaccine\| PubMed ID: 28780981	2017
Pulmonary inflammation and cytokine dynamics of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during A(H1N1)pdm09 influenza infection. Scientific reports\| PubMed ID: 28831046	2017
The road to a more effective influenza vaccine: Up to date studies and future prospects. Vaccine\| PubMed ID: 28866292	2017
cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue. Medical sciences (Basel, Switzerland)\| PubMed ID: 29258267	2017
Neutralizing Antibodies Induced by Gene-Based Hydrodynamic Injection Have a Therapeutic Effect in Lethal Influenza Infection. Frontiers in immunology\| PubMed ID: 29416543	2018
IgA polymerization contributes to efficient virus neutralization on human upper respiratory mucosa after intranasal inactivated influenza vaccine administration. Human vaccines & immunotherapeutics\| PubMed ID: 29425074	2018
Application of HTLV-1 tax transgenic mice for therapeutic intervention. Advances in biological regulation\| PubMed ID: 29588208	2018
Tuberculous pneumonia-induced severe ARDS complicated with DIC in a female child: a case of successful treatment. BMC infectious diseases\| PubMed ID: 29970013	2018
Intranasal inactivated influenza vaccines for the prevention of seasonal influenza epidemics. Expert review of vaccines\| PubMed ID: 30092690	2018
IgA tetramerization improves target breadth but not peak potency of functionality of anti-influenza virus broadly neutralizing antibody. PLoS pathogens\| PubMed ID: 30605488	2019