Gary R. Whittaker

Department of Microbiology and Immunology, Cornell University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 24	2019
Publication title Cited by 89	2019

Other Publications

Article	Year
Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins. Journal of virology\| PubMed ID: 10644350	2000
Dissecting virus entry via endocytosis. The Journal of general virology\| PubMed ID: 12075072	2002
Influenza virus can enter and infect cells in the absence of clathrin-mediated endocytosis. Journal of virology\| PubMed ID: 12239322	2002
Role of protein kinase C betaII in influenza virus entry via late endosomes. Journal of virology\| PubMed ID: 12477851	2003
Differential requirements of Rab5 and Rab7 for endocytosis of influenza and other enveloped viruses. Traffic (Copenhagen, Denmark)\| PubMed ID: 12713661	2003
Virus nuclear import. Advanced drug delivery reviews\| PubMed ID: 12788537	2003
Rab GTPases are recruited to chlamydial inclusions in both a species-dependent and species-independent manner. Infection and immunity\| PubMed ID: 14500507	2003
Role for influenza virus envelope cholesterol in virus entry and infection. Journal of virology\| PubMed ID: 14610177	2003
The ubiquitin-vacuolar protein sorting system is selectively required during entry of influenza virus into host cells. Traffic (Copenhagen, Denmark)\| PubMed ID: 14617349	2003
Influenza virus entry and infection require host cell N-linked glycoprotein. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15601777	2004
Role of clathrin-mediated endocytosis during vesicular stomatitis virus entry into host cells. Virology\| PubMed ID: 15936793	2005
The avian coronavirus infectious bronchitis virus undergoes direct low-pH-dependent fusion activation during entry into host cells. Journal of virology\| PubMed ID: 16537586	2006
Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p. Molecular and cellular biology\| PubMed ID: 16980630	2006
Fluorescence dequenching assays of coronavirus fusion. Advances in experimental medicine and biology\| PubMed ID: 17037536	2006
Avian infectious bronchitis virus enters cells via the endocytic pathway. Advances in experimental medicine and biology\| PubMed ID: 17037550	2006
Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus. Virology journal\| PubMed ID: 17324273	2007
Heparan sulfate is a selective attachment factor for the avian coronavirus infectious bronchitis virus Beaudette. Avian diseases\| PubMed ID: 17461266	2007
Role of the actin cytoskeleton during influenza virus internalization into polarized epithelial cells. Cellular microbiology\| PubMed ID: 17578407	2007
Molecular architecture of the bipartite fusion loops of vesicular stomatitis virus glycoprotein G, a class III viral fusion protein. The Journal of biological chemistry\| PubMed ID: 18165228	2008
Differential role for low pH and cathepsin-mediated cleavage of the viral spike protein during entry of serotype II feline coronaviruses. Veterinary microbiology\| PubMed ID: 18606506	2008
Utilization of DC-SIGN for entry of feline coronaviruses into host cells. Journal of virology\| PubMed ID: 18799586	2008
Activation of p38 MAPK by feline infectious peritonitis virus regulates pro-inflammatory cytokine production in primary blood-derived feline mononuclear cells. Virology\| PubMed ID: 19058829	2009
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19321428	2009
Characterization of a highly conserved domain within the severe acute respiratory syndrome coronavirus spike protein S2 domain with characteristics of a viral fusion peptide. Journal of virology\| PubMed ID: 19439480	2009
SARS-coronavirus spike S2 domain flanked by cysteine residues C822 and C833 is important for activation of membrane fusion. Virology\| PubMed ID: 19717178	2009
Feline lectin activity is critical for the cellular entry of feline infectious peritonitis virus. Journal of virology\| PubMed ID: 20484511	2010
Elastase-mediated activation of the severe acute respiratory syndrome coronavirus spike protein at discrete sites within the S2 domain. The Journal of biological chemistry\| PubMed ID: 20507992	2010
Modifications to the hemagglutinin cleavage site control the virulence of a neurotropic H1N1 influenza virus. Journal of virology\| PubMed ID: 20554779	2010
Promotion of vesicular stomatitis virus fusion by the endosome-specific phospholipid bis(monoacylglycero)phosphate (BMP). FEBS letters\| PubMed ID: 21333650	2011
Expression of the C-type lectins DC-SIGN or L-SIGN alters host cell susceptibility for the avian coronavirus, infectious bronchitis virus. Veterinary microbiology\| PubMed ID: 22340967	2012
Characterization of a recombinant canine coronavirus with a distinct receptor-binding (S1) domain. Virology\| PubMed ID: 22609354	2012
Cleavage activation of the human-adapted influenza virus subtypes by matriptase reveals both subtype and strain specificities. Journal of virology\| PubMed ID: 22811538	2012
Mechanisms of coronavirus cell entry mediated by the viral spike protein. Viruses\| PubMed ID: 22816037	2012
Influenza virus-mediated membrane fusion: determinants of hemagglutinin fusogenic activity and experimental approaches for assessing virus fusion. Viruses\| PubMed ID: 22852045	2012
Influenza virus-membrane fusion triggered by proton uncaging for single particle studies of fusion kinetics. Analytical chemistry\| PubMed ID: 22974237	2012
Acquisition of a novel eleven amino acid insertion directly N-terminal to a tetrabasic cleavage site confers intracellular cleavage of an H7N7 influenza virus hemagglutinin. Virology\| PubMed ID: 23051710	2012
Plasmin-mediated activation of pandemic H1N1 influenza virus hemagglutinin is independent of the viral neuraminidase. Journal of virology\| PubMed ID: 23449787	2013
Internalization and fusion mechanism of vesicular stomatitis virus and related rhabdoviruses. Future virology\| PubMed ID: 23516023	2010
Cleavage activation of human-adapted influenza virus subtypes by kallikrein-related peptidases 5 and 12. The Journal of biological chemistry\| PubMed ID: 23612974	2013
Mutation in spike protein cleavage site and pathogenesis of feline coronavirus. Emerging infectious diseases\| PubMed ID: 23763835	2013
Entry of influenza virus. Advances in experimental medicine and biology\| PubMed ID: 23884586	2013
Entry of rhabdoviruses into animal cells. Advances in experimental medicine and biology\| PubMed ID: 23884591	2013
Single particle assay of coronavirus membrane fusion with proteinaceous receptor-embedded supported bilayers. Biomaterials\| PubMed ID: 23886734	2013
Utilization of human DC-SIGN and L-SIGN for entry and infection of host cells by the New World arenavirus, Junín virus. Biochemical and biophysical research communications\| PubMed ID: 24183720	2013
A novel activation mechanism of avian influenza virus H9N2 by furin. Journal of virology\| PubMed ID: 24257604	2014
Influenza entry pathways in polarized MDCK cells. Biochemical and biophysical research communications\| PubMed ID: 24878525	2014
Inhibition of influenza virus infection and hemagglutinin cleavage by the protease inhibitor HAI-2. Biochemical and biophysical research communications\| PubMed ID: 24978308	2014
Canine enteric coronaviruses: emerging viral pathogens with distinct recombinant spike proteins. Viruses\| PubMed ID: 25153347	2014
Genotypic characterization of canine coronaviruses associated with fatal canine neonatal enteritis in the United States. Journal of clinical microbiology\| PubMed ID: 25253797	2014
Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25288733	2014
Variations in pH sensitivity, acid stability, and fusogenicity of three influenza virus H3 subtypes. Journal of virology\| PubMed ID: 25320308	2015
Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis. Virus research\| PubMed ID: 25445340	2015
Modification of the hemagglutinin cleavage site allows indirect activation of avian influenza virus H9N2 by bacterial staphylokinase. Virology\| PubMed ID: 25841078	2015
Human transferrin receptor triggers an alternative Tacaribe virus internalization pathway. Archives of virology\| PubMed ID: 26559962	2016
Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice. Vaccine\| PubMed ID: 26827663	2016
Fusion of Enveloped Viruses in Endosomes. Traffic (Copenhagen, Denmark)\| PubMed ID: 26935856	2016
Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin. Antiviral research\| PubMed ID: 27424494	2016
Viral fusion efficacy of specific H3N2 influenza virus reassortant combinations at single-particle level. Scientific reports\| PubMed ID: 27752100	2016
A camel-derived MERS-CoV with a variant spike protein cleavage site and distinct fusion activation properties. Emerging microbes & infections\| PubMed ID: 27999426	2016
Murine Leukemia Virus (MLV)-based Coronavirus Spike-pseudotyped Particle Production and Infection. Bio-protocol\| PubMed ID: 28018942	2016
Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 28215994	2017
A peptide-based approach to evaluate the adaptability of influenza A virus to humans based on its hemagglutinin proteolytic cleavage site. PloS one\| PubMed ID: 28358853	2017
Use of AAScatterPlot tool for monitoring the evolution of the hemagglutinin cleavage site in H9 avian influenza viruses. Bioinformatics (Oxford, England)\| PubMed ID: 28383669	2017
A single dose and long lasting vaccine against pandemic influenza through the controlled release of a heterospecies tandem M2 sequence embedded within detoxified bacterial outer membrane ves... Vaccine\| PubMed ID: 28866291	2017
The SARS-CoV Fusion Peptide Forms an Extended Bipartite Fusion Platform that Perturbs Membrane Order in a Calcium-Dependent Manner. Journal of molecular biology\| PubMed ID: 29056462	2017
Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells. Virology\| PubMed ID: 29275820	2018
Improving Virus Taxonomy by Recontextualizing Sequence-Based Classification with Biologically Relevant Data: the Case of the Species. mSphere\| PubMed ID: 29299531	2018
Feline coronavirus: Insights into viral pathogenesis based on the spike protein structure and function. Virology\| PubMed ID: 29329682	2018
Characterizing replication kinetics and plaque production of type I feline infectious peritonitis virus in three feline cell lines. Virology\| PubMed ID: 30205273	2018