identifying-cell-surface-markers-primary-neural-stem-progenitor-cells

Identifying Cell Surface Markers of Primary Neural Stem and Progenitor Cells by Metabolic Labeling of Sialoglycan

Neural stem and progenitor cells (NSPCs) are the cellular basis for the complex structures and functions of the brain. They are located in specialized ...

Tongji University and Frontier Science Research Center for Stem Cells of Ministry of Education

Chromatin modifications play an important role in cortical neurogenesis. In this issue, Baizabal et al. (2018) show how PRDM16, a histone methyltransferase, influences upper layer neuron production and migration by pre-setting enhancer activity within the developmental radial glial lineage.

Influence without Presence: PRDM16 Casts Destiny.

Recently in Cell, Berg et al. (2019) show that Hopx-expressing neural progenitor cells in the embryonic dentate gyrus contribute to dentate neurogenesis through the embryonic to adult stage, exhibiting a common transcriptomic and epigenomic signature and developmental dynamics. This finding suggests a continuous model for neurogenesis in the dentate gyrus.

Article	Year
Influence without Presence: PRDM16 Casts Destiny. Neuron\| PubMed ID: 29879386	2018
All Roads Lead to Rome: Hippocampal Stem Cells Hop(x) the Continuous Way. Cell stem cell\| PubMed ID: 31051131	2019

Qin Shen

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