Pierre Magistretti

Pierre Magistretti

Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology

Affiliated withKing Abdullah University of Science and Technology

Research Area

Biography

Pierre J. Magistretti received his MD in 1979 from the University of Geneva and his Ph.D. in Biology in 1982 from UCSD. His laboratory has discovered some of the cellular and molecular mechanisms that underlie the coupling between neuronal activity and energy consumption by revealing the key role that glial cells, in particular, astrocytes, play in this physiological process. These findings are particularly relevant for understanding the origin of the signals detected by functional brain imaging and are revealing the role of astrocytes in neuronal plasticity and neuroprotection. He is strongly engaged in the public understanding of neuroscience.

JoVE Journal Publications

ArticleTotal : 1
Year
A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells
Publication title

Cited by 11

2019

Other Publications

Article
Year
Genes involved in the astrocyte-neuron lactate shuttle (ANLS) are specifically regulated in cortical astrocytes following sleep deprivation in mice.

Sleep| PubMed ID: 24082304

2013
Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 25071212

2014
2014
2015
2014
Methylglyoxal, the dark side of glycolysis.

Frontiers in neuroscience| PubMed ID: 25709564

2015
2015
2015
2015
2015
2015
2016
2015
2016
Goals in Nutrition Science 2015-2020.

Frontiers in nutrition| PubMed ID: 26442272

2015
2015
2016
2016
2016
2016
2016
2016
Imaging brain aerobic glycolysis as a marker of synaptic plasticity.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 27317739

2016
Astrocytic β2-adrenergic receptors mediate hippocampal long-term memory consolidation.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 27402767

2016
Lactate release from astrocytes to neurons contributes to cocaine memory formation.

BioEssays : news and reviews in molecular, cellular and developmental biology| PubMed ID: 27699812

2016
Role of MCT1 and CAII in skeletal muscle pH homeostasis, energetics, and function: insights from MCT1 haploinsufficient mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 28254758

2017
2017
2017
2018
Lactate in the brain: from metabolic end-product to signalling molecule.

Nature reviews. Neuroscience| PubMed ID: 29515192

2018
Impact of MCT1 Haploinsufficiency on the Mouse Retina.

Advances in experimental medicine and biology| PubMed ID: 29721966

2018
2018
At the Heart of Genome Editing and Cardiovascular Diseases.

Circulation research| PubMed ID: 29976689

2018
2018
2018
2018
2018
The Epistemological Foundations of Freud's Energetics Model.

Frontiers in psychology| PubMed ID: 30364323

2018
2019
2019
2019
Gangliosides: Treatment Avenues in Neurodegenerative Disease.

Frontiers in neurology| PubMed ID: 31447771

2019
2019