Constantinos M. Mikelis

Department of Pharmaceutical Sciences, Texas Tech University Health Sciences Center

Affiliated withTexas Tech University Health Sciences Center University of Patras

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 9	2019
Publication title Cited by 1	2023

Other Publications

Article	Year
Multipronged activity of combinatorial miR-143 and miR-506 inhibits Lung Cancer cell cycle progression and angiogenesis in vitro. Scientific reports\| PubMed ID: 30002440	2018
Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells. Oncogene\| PubMed ID: 26616858	2016
CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System. PLoS pathogens\| PubMed ID: 26679537	2015
Extrapulmonary infection in patients with CARD9 deficiency. JCI insight\| PubMed ID: 27777981	2016
Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes. PloS one\| PubMed ID: 28301547	2017
Mechanisms of angiogenesis in microbe-regulated inflammatory and neoplastic conditions. Angiogenesis\| PubMed ID: 29110215	2018
The homozygous CX3CR1-M280 mutation impairs human monocyte survival. JCI insight\| PubMed ID: 29415879	2018
GM-CSF therapy in human caspase recruitment domain-containing protein 9 deficiency. The Journal of allergy and clinical immunology\| PubMed ID: 29890237	2018
Conception, synthesis, and characterization of a rofecoxib-combretastatin hybrid drug with potent cyclooxygenase-2 (COX-2) inhibiting and microtubule disrupting activities in colon cancer ce... Oncotarget\| PubMed ID: 29899846	2018
Analogs of penfluridol as chemotherapeutic agents with reduced central nervous system activity. Bioorganic & medicinal chemistry letters\| PubMed ID: 30389290	2018
DNA Repair Response Adaptors: Novel Targets for Vasoproliferative Retinopathy? Thrombosis and haemostasis\| PubMed ID: 30620993	2019
In Vitro Spheroid Sprouting Assay of Angiogenesis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 30825177	2019
Matrigel Plug Assay for In Vivo Evaluation of Angiogenesis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 30825178	2019
Role of Angiopoietin-2 in Vascular Physiology and Pathophysiology. Cells\| PubMed ID: 31108880	2019
In Vitro Wound Healing Assays to Investigate Epidermal Migration. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31123996	2020
Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis. Scientific reports\| PubMed ID: 31406143	2019
Nanoparticle Delivery and Tumor Vascular Normalization: The Chicken or The Egg? Frontiers in oncology\| PubMed ID: 31799190	2019
Low Dose of Penfluridol Inhibits VEGF-Induced Angiogenesis. International journal of molecular sciences\| PubMed ID: 31979394	2020
Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling. Nature communications\| PubMed ID: 32139674	2020
Assessing the Current State of Lung Cancer Chemoprevention: A Comprehensive Overview. Cancers\| PubMed ID: 32429547	2020
S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI insight\| PubMed ID: 32544090	2020
Pleiotrophin selectively binds to vascular endothelial growth factor receptor 2 and inhibits or stimulates cell migration depending on αβ integrin expression. Angiogenesis\| PubMed ID: 32681389	2020
Investigating Epidermal Interactions Through an In Vivo Cutaneous Wound-Healing Assay. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 32808253	2021
In Vivo Ear Sponge Lymphangiogenesis Assay. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 32808261	2021
Identification of Rho GEF and RhoA Activation by Pull-Down Assays. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 32808262	2021
Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. European journal of medicinal chemistry\| PubMed ID: 33039722	2021
An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening. ACS pharmacology & translational science\| PubMed ID: 33073192	2020
Glycolysis is integral to histamine-induced endothelial hyperpermeability. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 33566443	2021
Delayed Exercise-induced Upregulation of Angiogenic Proteins and Recovery of Motor Function after Photothrombotic Stroke in Mice. Neuroscience\| PubMed ID: 33667592	2021
Advanced bioinformatic analysis and pathway prediction of NSCLC cells upon cisplatin resistance. Scientific reports\| PubMed ID: 33753779	2021
Role of bFGF in Acquired Resistance upon Anti-VEGF Therapy in Cancer. Cancers\| PubMed ID: 33804681	2021
Targeting the Angiopoietin/Tie Pathway: Prospects for Treatment of Retinal and Respiratory Disorders. Drugs\| PubMed ID: 34586603	2021
Protein tyrosine phosphatase receptor-ζ1 deletion triggers defective heart morphogenesis in mice and zebrafish. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 34767486	2022
MiRNAs as Anti-Angiogenic Adjuvant Therapy in Cancer: Synopsis and Potential. Frontiers in oncology\| PubMed ID: 34956857	2021
Evaluation of Urea-Based Inhibitors of the Dopamine Transporter Using the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. ACS chemical neuroscience\| PubMed ID: 34978174	2022
Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis. Angiogenesis\| PubMed ID: 35103877	2022
Chlorinated benzothiadiazines inhibit angiogenesis through suppression of VEGFR2 phosphorylation. Bioorganic & medicinal chemistry\| PubMed ID: 35635929	2022
An in vitro model of glucose transporter 1 deficiency syndrome at the blood-brain barrier using induced pluripotent stem cells. Journal of neurochemistry\| PubMed ID: 35943296	2022
Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis. The Journal of clinical investigation\| PubMed ID: 36377664	2022
Chlorotoxin and Lung Cancer: A Targeting Perspective for Drug Delivery. Pharmaceutics\| PubMed ID: 36559106	2022
Endothelial-Specific Targeting of RhoA Signaling via CD31 Antibody-Conjugated Nanoparticles. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 36746610	2023
Genetic deletion or tyrosine phosphatase inhibition of PTPRZ1 activates c-Met to up-regulate angiogenesis and lung adenocarcinoma growth. International journal of cancer\| PubMed ID: 37260355	2023