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Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis

Article DOI: 10.3791/59460-v • 11:44 min • March 30th, 2019
March 30th, 2019 •
1, 1, 2, 3, 1, 1, 2, 1
1School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, 2Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, 3Department of Obstetrics and Gynecology, School of Medicine, Texas Tech University Health Sciences Center

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Summary
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miRNA therapeutics have significant potential in regulating cancer progression. Demonstrated here are analytical approaches used for identification of the activity of a combinatorial miRNA treatment in halting cell cycle and angiogenesis.

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Combinatorial MiRNA Treatments Regulate Cell Cycle Angiogenesis Lung Cancer Cells Lab Techniques MicroRNA 143 MicroRNA 506 Gene Expression Analysis Antibody Protein MicroRNA Cell Transfection RNA Extraction Quantitative Real Time PCR MicroRNA Analysis Gene Expression QPCR Micro-array Analysis
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