Sonja C. Vernes

Sonja C. Vernes

Neurogenetics of Vocal Communication, Max Planck Institute for Psycholinguistics

Affiliated withMax Planck Institute for PsycholinguisticsDonders Institute for Brain, Cognition and BehaviorMax Planck Institute for Psycholinguistics

Research Area

Biography

Sonja Vernes investigates how speech and language relevant traits are biologically encoded, how these abilities evolved, and the causes of language related disorders. During her DPhil at the University of Oxford she sought to understand the functions of genes that cause speech and language disorders. She demonstrated how patient mutations in one such gene, FOXP2, cause altered neurodevelopment in mouse and human models, and identified a relationship between FOXP2 and another gene known as CNTNAP2, showing that they represent a novel genetic mechanism shared across clinically distinct language-related syndromes.

In 2016, Dr. Vernes was awarded a Max Planck Research Group (MPRG) Grant and a Human Frontiers Science Program (HFSP) Research Grant to establish a research group at the Max Planck Institute for Psycholinguistics with the goal to use bats for comparative studies of speech and language relevant traits. Her lab, the Neurogenetics of Vocal Communication Group, focuses on the abilities of bats to learn novel vocalisations (vocal learning), a skill that in humans, allows us learn the huge repertoire of sounds we use to communicate via spoken language. Their work has now demonstrated the feasibility of neurogenetic studies in bats, identified sites of action for key language-related genes in the brains of vocal learning bats, and their potential to contribute to our understanding of human speech and language.

To facilitate the use of bats as a neurogenetic model Dr. Vernes, together with Dr. Emma Teeling (UC Dublin), launched the Bat1K genome sequencing consortium (www.bat1k.com). This international research effort is now underway to sequence the genomes of all living bat species to reference quality resolution.

Together, these new research area is allowing us to characterise the genetics and neural circuitry underlying vocal learning in mammals and will ultimately inform our understanding of spoken language in humans.

JoVE Journal Publications

ArticleTotal : 1
Year
Tissue Collection of Bats for -Omics Analyses and Primary Cell Culture
Publication title

Cited by 25

2019

Other Publications

Article
Year
Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.

PLoS genetics| PubMed ID: 21765815

2011
FOXP2 targets show evidence of positive selection in European populations.

American journal of human genetics| PubMed ID: 23602712

2013
Shining a light on CNTNAP2: complex functions to complex disorders.

European journal of human genetics : EJHG| PubMed ID: 23714751

2014
2014
2014
2014
2015
2015
2015
2016
2016
What bats have to say about speech and language.

Psychonomic bulletin & review| PubMed ID: 27368623

2017
2018
2018
2018
Mapping of Human Enhancers Reveals Complex Regulation.

Frontiers in molecular neuroscience| PubMed ID: 29515369

2018
Taking turns: bridging the gap between human and animal communication.

Proceedings. Biological sciences| PubMed ID: 29875303

2018
Volitional control of social vocalisations and vocal usage learning in bats.

The Journal of experimental biology| PubMed ID: 29880634

2018
2018
2018
2019