Angelo C. Lepore

Department of Neuroscience, Thomas Jefferson University Medical College

Affiliated withThomas Jefferson University Medical College Sidney Kimmel Medical College at Thomas Jefferson University

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 30	2011
Publication title Cited by 16	2015

Other Publications

Article	Year
Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord. Brain research\| PubMed ID: 15910779	2005
Transplantation of neuronal and glial restricted precursors into contused spinal cord improves bladder and motor functions, decreases thermal hypersensitivity, and modifies intraspinal circu... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16237167	2005
Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult CNS. Neuron glia biology\| PubMed ID: 16520830	2004
Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS. Brain research\| PubMed ID: 17963733	2007
Adult glial precursor proliferation in mutant SOD1G93A mice. Glia\| PubMed ID: 18023016	2008
Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration. Experimental neurology\| PubMed ID: 18410928	2008
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nature neuroscience\| PubMed ID: 18931666	2008
Peripheral hyperstimulation alters site of disease onset and course in SOD1 rats. Neurobiology of disease\| PubMed ID: 20381620	2010
Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury. Journal of neuroscience research\| PubMed ID: 21488085	2011
Reduction in expression of the astrocyte glutamate transporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury. Glia\| PubMed ID: 21882244	2011
Stem cell transplantation for spinal cord neurodegeneration. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21913120	2011
Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21969586	2011
Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS. PloS one\| PubMed ID: 21998733	2011
Phrenic motor neuron degeneration compromises phrenic axonal circuitry and diaphragm activity in a unilateral cervical contusion model of spinal cord injury. Experimental neurology\| PubMed ID: 22465264	2012
Degeneration of phrenic motor neurons induces long-term diaphragm deficits following mid-cervical spinal contusion in mice. Journal of neurotrauma\| PubMed ID: 23176637	2012
Early phrenic motor neuron loss and transient respiratory abnormalities after unilateral cervical spinal cord contusion. Journal of neurotrauma\| PubMed ID: 23534670	2013
Chronic at-level thermal hyperalgesia following rat cervical contusion spinal cord injury is accompanied by neuronal and astrocyte activation and loss of the astrocyte glutamate transporter,... Brain research\| PubMed ID: 24833066	2014
Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion sp... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24872566	2014
Immunohistochemical toolkit for tracking and quantifying xenotransplanted human stem cells. Regenerative medicine\| PubMed ID: 25159062	2014
Therapeutically targeting astrocytes with stem and progenitor cell transplantation following traumatic spinal cord injury. Brain research\| PubMed ID: 25251595	2014
Persistent at-level thermal hyperalgesia and tactile allodynia accompany chronic neuronal and astrocyte activation in superficial dorsal horn following mouse cervical contusion spinal cord i... PloS one\| PubMed ID: 25268642	2014
Transplantation of glial progenitors that overexpress glutamate transporter GLT1 preserves diaphragm function following cervical SCI. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 25492561	2015
Inhibiting drug efflux transporters improves efficacy of ALS therapeutics. Annals of clinical and translational neurology\| PubMed ID: 25574474	2014
Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25609640	2015
Transplantation of stem cell-derived astrocytes for the treatment of amyotrophic lateral sclerosis and spinal cord injury. World journal of stem cells\| PubMed ID: 25815122	2015
GLT1 overexpression in SOD1(G93A) mouse cervical spinal cord does not preserve diaphragm function or extend disease. Neurobiology of disease\| PubMed ID: 25818008	2015