Rui Monteiro

Rui Monteiro

MRC Molecular Haematology Unit, University of Oxford

Affiliated withUniversity of OxfordBHF Centre of Research ExcellenceUniversity of Birmingham

Research Area

Biography

Dr Rui Monteiro is a BHF Intermediate Basic Science Research Fellow and Birmingham Fellow at the University of Birmingham, UK. He graduated in Biochemistry from the University of Lisbon, Portugal and earned his PhD in Developmental Biology with Prof Christine Mummery at the Hubrecht Institute in Utrecht, The Netherlands.

During his PhD he developed a keen interest in the TGF/BMP signalling pathway. There, he generated transgenic reporters in mice to map BMP activity during embryonic development in mice and also identified the two zebrafish BMP type II receptors required for left-right asymmetry. In 2006, he joined Profr Roger Patient’s lab at the Weatherall Institute, University of Oxford to learn about developmental haematopoiesis and transcriptional regulation of cell fate decisions.

Dr Monteiro received a BHF Intermediate Basic Science Fellowship in 2014 to establish his own research group in the Radcliffe Department of Medicine at the University of Oxford, investigating TGF signalling and its role in the formation on blood stem cells. In 2016 he became a University Research Lecturer at Oxford and in 2018 he was recruited as faculty at the Institute of Cancer and Genomic Sciences, University of Birmingham. His lab research programme is focussed on the study of transcription factors and DNA elements (enhancers) that function to establish the genetic programming of haemogenic endothelial cells and blood stem cells, both in development and in disease.

JoVE Journal Publications

ArticleTotal : 1
Year
Genotyping and Quantification of In Situ Hybridization Staining in Zebrafish
Publication title

Cited by 25

2020

Other Publications

Article
Year
A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells.

Molecular and cellular biology| PubMed ID: 22801375

2012
Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23818617

2013
2014
2015
2016
2016
2016
2018
2019
2020