Cliona O'Farrelly

School of Biochemistry and Immunology, Trinity College Dublin

Research Area

Biography

Cliona O'Farrelly has not added Biography.
If you are Cliona O'Farrelly and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2019

Other Publications

Article	Year
Induction of a novel chicken Toll-like receptor following Salmonella enterica serovar Typhimurium infection. Infection and immunity\| PubMed ID: 16495540	2006
Evolution, expression and effectiveness in a cluster of novel bovine beta-defensins. Immunogenetics\| PubMed ID: 18369613	2008
Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18802051	2008
Antigen stimulation of peripheral blood mononuclear cells from Mycobacterium bovis infected cattle yields evidence for a novel gene expression program. BMC genomics\| PubMed ID: 18823559	2008
Differential antimicrobial peptide gene expression patterns during early chicken embryological development. Developmental and comparative immunology\| PubMed ID: 19007808	2009
Toll-like receptor and antimicrobial peptide expression in the bovine endometrium. Reproductive biology and endocrinology : RB&E\| PubMed ID: 19017375	2008
Natural killer cells in obesity: impaired function and increased susceptibility to the effects of cigarette smoke. PloS one\| PubMed ID: 20107494	2010
Clinical anxiety, cortisol and interleukin-6: evidence for specificity in emotion-biology relationships. Brain, behavior, and immunity\| PubMed ID: 20227485	2010
Experimental Staphylococcus aureus infection of the mammary gland induces region-specific changes in innate immune gene expression. Veterinary immunology and immunopathology\| PubMed ID: 21292330	2011
Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion. Hepatology (Baltimore, Md.)\| PubMed ID: 21452285	2011
Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide. Clinical immunology (Orlando, Fla.)\| PubMed ID: 21493160	2011
Risk factors for the development of depression in patients with hepatitis C taking interferon-α. Neuropsychiatric disease and treatment\| PubMed ID: 21654873	2011
Preparation of pre-confluent retinal cells increases graft viability in vitro and in vivo: a mouse model. PloS one\| PubMed ID: 21738643	2011
Ribavirin enhances IFN-α signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV. PloS one\| PubMed ID: 22114715	2011
Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes. BMC genomics\| PubMed ID: 22182502	2011
Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production. Immunity\| PubMed ID: 22981538	2012
Global endometrial transcriptomic profiling: transient immune activation precedes tissue proliferation and repair in healthy beef cows. BMC genomics\| PubMed ID: 22985206	2012
Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes. FEBS letters\| PubMed ID: 23587486	2013
CD141⁺ myeloid dendritic cells are enriched in healthy human liver. Journal of hepatology\| PubMed ID: 23968887	2014
Reply to: "Dendritic cell subset composition in the human liver is more complex than it seems". Journal of hepatology\| PubMed ID: 24418016	2014
Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1α-dependent inflammation. Diabetes\| PubMed ID: 24458363	2014
Characterisation and expression profile of the bovine cathelicidin gene repertoire in mammary tissue. BMC genomics\| PubMed ID: 24524771	2014
Hepatitis C virus (HCV)-induced suppressor of cytokine signaling (SOCS) 3 regulates proinflammatory TNF-α responses. Journal of leukocyte biology\| PubMed ID: 24659790	2014
IFNL cytokines do not modulate human or murine NK cell functions. Human immunology\| PubMed ID: 24994459	2014
In vitro blood cell responsiveness to IFN-α predicts clinical response independently of IL28B in hepatitis C virus genotype 1 infected patients. Journal of translational medicine\| PubMed ID: 25048205	2014
RNA-seq Transcriptional Profiling of Peripheral Blood Leukocytes from Cattle Infected with Mycobacterium bovis. Frontiers in immunology\| PubMed ID: 25206354	2014
Tissue-specific NK cell populations and their origin. Journal of leukocyte biology\| PubMed ID: 25246601	2014
Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic and interleukin-6 genes. Psychiatric genetics\| PubMed ID: 25350786	2015
The Role of microRNAs in Bovine Infection and Immunity. Frontiers in immunology\| PubMed ID: 25505900	2014
Natural Killer Cells: Key Players in Endometriosis. American journal of reproductive immunology (New York, N.Y. : 1989)\| PubMed ID: 26104509	2015
Increased uNK Progenitor Cells in Women With Endometriosis and Infertility are Associated With Low Levels of Endometrial Stem Cell Factor. American journal of reproductive immunology (New York, N.Y. : 1989)\| PubMed ID: 26791471	2016
Myeloid Engraftment in Humanized Mice: Impact of Granulocyte-Colony Stimulating Factor Treatment and Transgenic Mouse Strain. Stem cells and development\| PubMed ID: 26879149	2016
CCR1 antagonism attenuates T cell trafficking to omentum and liver in obesity-associated cancer. Immunology and cell biology\| PubMed ID: 27046081	2016
Liver immunology and its role in inflammation and homeostasis. Cellular & molecular immunology\| PubMed ID: 27063467	2016
Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection. Gut\| PubMed ID: 27196570	2017
The microenvironment of visceral adipose tissue and liver alter natural killer cell viability and function. Journal of leukocyte biology\| PubMed ID: 27365528	2016
Tissue-resident Eomes(hi) T-bet(lo) CD56(bright) NK cells with reduced proinflammatory potential are enriched in the adult human liver. European journal of immunology\| PubMed ID: 27485474	2016
The CD4(+) T cell methylome contributes to a distinct CD4(+) T cell transcriptional signature in Mycobacterium bovis-infected cattle. Scientific reports\| PubMed ID: 27507428	2016
Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 27617757	2016
A novel anti-viral role for STAT3 in IFN-α signalling responses. Cellular and molecular life sciences : CMLS\| PubMed ID: 27988795	2017
Early Subretinal Allograft Rejection Is Characterized by Innate Immune Activity. Cell transplantation\| PubMed ID: 28105976	2017
Disease outcomes in a cohort of women in Ireland infected by hepatitis C-contaminated anti-D immunoglobulin during 1970s. Journal of hepatology\| PubMed ID: 28843656	2017
Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma. Cancer letters\| PubMed ID: 29339209	2018
Uterine natural killer cell progenitor populations predict successful implantation in women with endometriosis-associated infertility. American journal of reproductive immunology (New York, N.Y. : 1989)\| PubMed ID: 29380456	2018
Depleted polymorphonuclear leukocytes in human metastatic liver reflect an altered immune microenvironment associated with recurrent metastasis. Cancer immunology, immunotherapy : CII\| PubMed ID: 29572702	2018
HIV-1 Promotes the Degradation of Components of the Type 1 IFN JAK/STAT Pathway and Blocks Anti-viral ISG Induction. EBioMedicine\| PubMed ID: 29580840	2018
Designer human tissue: coming to a lab near you. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 29786548	2018
Innate immunity in stem cell-derived hepatocytes. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 29786555	2018
Cervico-vaginal mucus (CVM) - an accessible source of immunologically informative biomolecules. Veterinary research communications\| PubMed ID: 30117040	2018
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses. Nature immunology\| PubMed ID: 30420624	2018
Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of Liver-Resident NK Cells in Colorectal Liver Metastasis. Cancer immunology research\| PubMed ID: 30563827	2019
β-Defensins: Farming the Microbiome for Homeostasis and Health. Frontiers in immunology\| PubMed ID: 30761155	2018
Non-canonical Inflammasome-Mediated IL-1β Production by Primary Endometrial Epithelial and Stromal Fibroblast Cells Is NLRP3 and Caspase-4 Dependent. Frontiers in immunology\| PubMed ID: 30804935	2019
The hepatitis C virus (HCV) protein, p7, suppresses inflammatory responses to tumor necrosis factor (TNF)-α signal transducer and activator of transcription (STAT)3 and extracellular signal... FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 31163989	2019