Anders Nykjaer

The Lundbeck Foundation Research Center MIND, Aarhus University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 97	2011

Other Publications

Article	Year
Pathways for kidney-specific uptake of the steroid hormone 25-hydroxyvitamin D3. Current opinion in lipidology\| PubMed ID: 12045394	2002
The low-density lipoprotein receptor gene family: a cellular Swiss army knife? Trends in cell biology\| PubMed ID: 12074887	2002
Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism. Kidney international\| PubMed ID: 12371967	2002
低钙血症和肾特定 megalin 基因小鼠骨病缺损。 FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12475886	2003
From holoprosencephaly to osteopathology: role of multifunctional endocytic receptors in absorptive epithelia. Annals of medicine\| PubMed ID: 12952015	2003
Sortilin is essential for proNGF-induced neuronal cell death. Nature\| PubMed ID: 14985763	2004
The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein... The Biochemical journal\| PubMed ID: 15053742	2004
Functional organization of the sortilin Vps10p domain. The Journal of biological chemistry\| PubMed ID: 15364913	2004
p75NTR--live or let die. Current opinion in neurobiology\| PubMed ID: 15721744	2005
ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15930396	2005
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15987945	2005
Role of endocytosis in cellular uptake of sex steroids. Cell\| PubMed ID: 16143106	2005
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16174740	2005
Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members. The Biochemical journal\| PubMed ID: 16393139	2006
Hyporesponsiveness to glucocorticoids in mice genetically deficient for the corticosteroid binding globulin. Molecular and cellular biology\| PubMed ID: 16980625	2006
Inhibition of PDGF-BB by Factor VII-activating protease (FSAP) is neutralized by protease nexin-1, and the FSAP-inhibitor complexes are internalized via LRP. The Biochemical journal\| PubMed ID: 17298300	2007
Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury. Nature neuroscience\| PubMed ID: 17934455	2007
Different motifs regulate trafficking of SorCS1 isoforms. Traffic (Copenhagen, Denmark)\| PubMed ID: 18315530	2008
VPS10P-domain receptors - regulators of neuronal viability and function. Nature reviews. Neuroscience\| PubMed ID: 19002190	2008
Cubilin and megalin co-localize in the neonatal inner ear. Audiology & neuro-otology\| PubMed ID: 19202329	2009
Assessing low-dose gentamicin-induced kidney injury in rats by analysis of urine. Journal of pharmacological and toxicological methods\| PubMed ID: 19632345	2009
Cellular uptake of steroid carrier proteins--mechanisms and implications. Molecular and cellular endocrinology\| PubMed ID: 19646505	2010
Mature BDNF, but not proBDNF, reduces excitability of fast-spiking interneurons in mouse dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19812317	2009
Brain-derived neurotrophic factor reduces amyloidogenic processing through control of SORLA gene expression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20007471	2009
Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease. Neuroscience letters\| PubMed ID: 20085800	2010
Identification of a linear epitope in sortilin that partakes in pro-neurotrophin binding. The Journal of biological chemistry\| PubMed ID: 20159974	2010
SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na(+)-K(+)-Cl(-) cotransporter 2. Molecular and cellular biology\| PubMed ID: 20385770	2010
Golgi-to-phagosome transport of acid sphingomyelinase and prosaposin is mediated by sortilin. Journal of cell science\| PubMed ID: 20571055	2010
Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export. Cell metabolism\| PubMed ID: 20816088	2010
APP involvement in retinogenesis of mice. Acta neuropathologica\| PubMed ID: 20978902	2011
Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. Neuron\| PubMed ID: 21092856	2010
Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nature neuroscience\| PubMed ID: 21102451	2011
Sortilins: new players in lipoprotein metabolism. Current opinion in lipidology\| PubMed ID: 21124217	2011
Proneurotrophin-3 may induce Sortilin-dependent death in inner ear neurons. The European journal of neuroscience\| PubMed ID: 21261755	2011
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking. Journal of cell science\| PubMed ID: 21385844	2011
Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: Neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and ... BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 21717487	2011
Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation. The Journal of biological chemistry\| PubMed ID: 21730062	2011
Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease. The EMBO journal\| PubMed ID: 21989385	2012
Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22279231	2012
The Loop Diuretic Bumetanide Blocks Posttraumatic p75NTR Upregulation and Rescues Injured Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22302815	2012