Suzanne Jackowski

Department of Infectious Diseases, St. Jude Children's Research Hospital

Affiliated withSt. Jude Children's Research Hospital

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2019

Other Publications

Article	Year
Activity of the phosphatidylcholine biosynthetic pathway modulates the distribution of fatty acids into glycerolipids in proliferating cells. Biochimica et biophysica acta\| PubMed ID: 10666565	2000
Modulation of CTP:phosphocholine cytidylyltransferase by membrane curvature elastic stress. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 10908674	2000
The licC gene of Streptococcus pneumoniae encodes a CTP:phosphocholine cytidylyltransferase. Journal of bacteriology\| PubMed ID: 11466299	2001
Structure and mechanism of CTP:phosphocholine cytidylyltransferase (LicC) from Streptococcus pneumoniae. The Journal of biological chemistry\| PubMed ID: 11706035	2002
A missense mutation in the fabB (beta-ketoacyl-acyl carrier protein synthase I) gene confers tiolactomycin resistance to Escherichia coli. Antimicrobial agents and chemotherapy\| PubMed ID: 11959552	2002
Forty years of bacterial fatty acid synthesis. Biochemical and biophysical research communications\| PubMed ID: 11969206	2002
The murine pantothenate kinase (Pank1) gene encodes two differentially regulated pantothenate kinase isozymes. Gene\| PubMed ID: 12095677	2002
Role of feedback regulation of pantothenate kinase (CoaA) in control of coenzyme A levels in Escherichia coli. Journal of bacteriology\| PubMed ID: 12754240	2003
Gene structure, expression and identification of a new CTP:phosphocholine cytidylyltransferase beta isoform. Biochimica et biophysica acta\| PubMed ID: 12842190	2003
PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression. Journal of lipid research\| PubMed ID: 14523052	2004
The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites. The Journal of biological chemistry\| PubMed ID: 15136582	2004
Disruption of CCTbeta2 expression leads to gonadal dysfunction. Molecular and cellular biology\| PubMed ID: 15143167	2004
Bacterial inhibition of phosphatidylcholine synthesis triggers apoptosis in the brain. The Journal of experimental medicine\| PubMed ID: 15238609	2004
Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites. The Journal of biological chemistry\| PubMed ID: 15459190	2004
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. The Journal of cell biology\| PubMed ID: 15466483	2004
CTP: Phosphocholine cytidylyltransferase: paving the way from gene to membrane. The Journal of biological chemistry\| PubMed ID: 15536089	2005
A pantothenate kinase from Staphylococcus aureus refractory to feedback regulation by coenzyme A. The Journal of biological chemistry\| PubMed ID: 15548531	2005
Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a). Molecular and cellular biology\| PubMed ID: 15798219	2005
Coenzyme A: back in action. Progress in lipid research\| PubMed ID: 15893380	2005
Feedback regulation of murine pantothenate kinase 3 by coenzyme A and coenzyme A thioesters. The Journal of biological chemistry\| PubMed ID: 16040613	2005
Biochemical properties of human pantothenate kinase 2 isoforms and mutations linked to pantothenate kinase-associated neurodegeneration. The Journal of biological chemistry\| PubMed ID: 16272150	2006
Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2. The Journal of biological chemistry\| PubMed ID: 16861741	2006
Role of phosphocholine cytidylyltransferase alpha in lung development. Molecular and cellular biology\| PubMed ID: 17130238	2007
Phospholipid biosynthesis program underlying membrane expansion during B-lymphocyte differentiation. The Journal of biological chemistry\| PubMed ID: 17213195	2007
Activation of human mitochondrial pantothenate kinase 2 by palmitoylcarnitine. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17242360	2007
Structure of the type III pantothenate kinase from Bacillus anthracis at 2.0 A resolution: implications for coenzyme A-dependent redox biology. Biochemistry\| PubMed ID: 17323930	2007
Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis. Chemistry & biology\| PubMed ID: 17379144	2007
Probucol therapy overcomes the reproductive defect in CTP: phosphocholine cytidylyltransferase beta2 knockout mice. Biochimica et biophysica acta\| PubMed ID: 17560827	2007
Localization and regulation of mouse pantothenate kinase 2. FEBS letters\| PubMed ID: 17825826	2007
Cytokine secretion requires phosphatidylcholine synthesis. The Journal of cell biology\| PubMed ID: 18559668	2008
Membrane phospholipid synthesis and endoplasmic reticulum function. Journal of lipid research\| PubMed ID: 18952570	2009
CTP:phosphocholine cytidylyltransferase alpha is required for B-cell proliferation and class switch recombination. The Journal of biological chemistry\| PubMed ID: 19139091	2009
ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum. Journal of cell science\| PubMed ID: 19420237	2009
Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. The Journal of biological chemistry\| PubMed ID: 19666474	2009
Pantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus. Journal of bacteriology\| PubMed ID: 19854913	2010
Phosphatidylcholine biosynthesis during neuronal differentiation and its role in cell fate determination. The Journal of biological chemistry\| PubMed ID: 20525991	2010
Pantothenate kinase 1 is required to support the metabolic transition from the fed to the fasted state. PloS one\| PubMed ID: 20559429	2010
Modulation of pantothenate kinase 3 activity by small molecules that interact with the substrate/allosteric regulatory domain. Chemistry & biology\| PubMed ID: 20797618	2010
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis. The EMBO journal\| PubMed ID: 21407177	2011
UPR-Mediated Membrane Biogenesis in B Cells. Biochemistry research international\| PubMed ID: 22110962	2012
Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation. The Journal of biological chemistry\| PubMed ID: 22442146	2012
The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells. Molecular immunology\| PubMed ID: 22555069	2012
Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism. PloS one\| PubMed ID: 22815849	2012
Phosphatidylcholine and the CDP-choline cycle. Biochimica et biophysica acta\| PubMed ID: 23010477	2013
Compartmentalization of Mammalian pantothenate kinases. PloS one\| PubMed ID: 23152917	2012
Preface: phospholipids and phospholipid metabolism. Biochimica et biophysica acta\| PubMed ID: 23369660	2013
Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance. Diabetologia\| PubMed ID: 24781151	2014
Coenzyme A and its derivatives: renaissance of a textbook classic. Biochemical Society transactions\| PubMed ID: 25109997	2014
Physiological roles of the pantothenate kinases. Biochemical Society transactions\| PubMed ID: 25109998	2014
Deregulated coenzyme A, loss of metabolic flexibility and diabetes. Biochemical Society transactions\| PubMed ID: 25110012	2014
A high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases. Journal of medicinal chemistry\| PubMed ID: 25569308	2015
The CDP-Ethanolamine Pathway Regulates Skeletal Muscle Diacylglycerol Content and Mitochondrial Biogenesis without Altering Insulin Sensitivity. Cell metabolism\| PubMed ID: 25955207	2015
Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in Mice. PloS one\| PubMed ID: 26052948	2015
Biosynthesis of Pantothenic Acid and Coenzyme A. EcoSal Plus\| PubMed ID: 26443589	2007
Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy. Molecular genetics and metabolism\| PubMed ID: 26549575	2015
Allosteric Regulation of Mammalian Pantothenate Kinase. The Journal of biological chemistry\| PubMed ID: 27555321	2016
T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions. The Journal of biological chemistry\| PubMed ID: 27903651	2017
Excess coenzyme A reduces skeletal muscle performance and strength in mice overexpressing human PANK2. Molecular genetics and metabolism\| PubMed ID: 28189602	2017
A therapeutic approach to pantothenate kinase associated neurodegeneration. Nature communications\| PubMed ID: 30352999	2018
Human pantothenate kinase 4 is a pseudo-pantothenate kinase. Protein science : a publication of the Protein Society\| PubMed ID: 30927326	2019
Proposed Therapies for Pantothenate-Kinase-Associated Neurodegeneration. Journal of experimental neuroscience\| PubMed ID: 31205425	2019
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in . Science translational medicine\| PubMed ID: 31534021	2019