Richard Finnell

Center for Environmental and Genetic Medicine, Texas A&M University (TAMU)

Affiliated withTexas A&M University (TAMU)

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title Cited by 9	2008
Publication title Cited by 4	2008
Publication title Cited by 3	2009
Publication title Cited by 1	2009

Other Publications

Article	Year
Molecular basis of environmentally induced birth defects. Annual review of pharmacology and toxicology\| PubMed ID: 11807170	2002
Effects of folate supplementation on the risk of spontaneous and induced neural tube defects in Splotch mice. Teratology\| PubMed ID: 11857507	2002
Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida. American journal of medical genetics\| PubMed ID: 11857541	2002
Apolipoprotein B and apolipoprotein E genotypes and sporadic holoprosencephaly. American journal of medical genetics\| PubMed ID: 11857554	2002
Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug. Epilepsia\| PubMed ID: 11903457	2002
Study of MTHFR and MS polymorphisms as risk factors for NTD in the Italian population. Journal of human genetics\| PubMed ID: 12111380	2002
DNA methylation in Folbp1 knockout mice supplemented with folic acid during gestation. The Journal of nutrition\| PubMed ID: 12163711	2002
Does prenatal screening for 5,10-methylenetetrahydrofolate reductase (MTHFR) mutations in high-risk neural tube defect pregnancies make sense? Genetic testing\| PubMed ID: 12180076	2002
Integration of DNA sample collection into a multi-site birth defects case-control study. Teratology\| PubMed ID: 12353214	2002
Apolipoprotein E and apolipoprotein B genotypes and risk for spina bifida. Teratology\| PubMed ID: 12397634	2002
Maternal periconceptional vitamins: interactions with selected factors and congenital anomalies? Epidemiology (Cambridge, Mass.)\| PubMed ID: 12410002	2002
Gene expression profiling within the developing neural tube. Neurochemical research\| PubMed ID: 12462415	2002
Lack of association between ZIC2 and ZIC3 genes and the risk of neural tube defects (NTDs) in Hispanic populations. American journal of medical genetics. Part A\| PubMed ID: 12522805	2003
Is Sonic hedgehog (SHH) a candidate gene for spina bifida? A pilot study. American journal of medical genetics. Part A\| PubMed ID: 12548748	2003
Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents. British journal of pharmacology\| PubMed ID: 12598414	2003
Maternal occupational chemical exposures and biotransformation genotypes as risk factors for selected congenital anomalies. American journal of epidemiology\| PubMed ID: 12631536	2003
Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects. Molecular genetics and metabolism\| PubMed ID: 12649067	2003
Reduced folate carrier polymorphism (80A-->G) and neural tube defects. European journal of human genetics : EJHG\| PubMed ID: 12673279	2003
Pathobiology and genetics of neural tube defects. Epilepsia\| PubMed ID: 12790882	2003
Evaluation of infant methylenetetrahydrofolate reductase genotype, maternal vitamin use, and risk of high versus low level spina bifida defects. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 12797455	2003
Risk factors for neural tube defects: associations between uncoupling protein 2 polymorphisms and spina bifida. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 12797456	2003
Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice. British journal of pharmacology\| PubMed ID: 12812999	2003
Neural and orofacial defects in Folp1 knockout mice [corrected]. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 12854656	2003
Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk. Molecular genetics and metabolism\| PubMed ID: 12855225	2003
Genetic dissection of hyperthermia-induced neural tube defects in mice. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 12962284	2003
Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of terat... Epilepsia\| PubMed ID: 14510821	2003
Gene-specific monitoring of T7-based RNA amplification by real-time quantitative PCR. BioTechniques\| PubMed ID: 14513555	2003
Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial and conotruncal heart defects. American journal of epidemiology\| PubMed ID: 14561664	2003
Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicology letters\| PubMed ID: 14581169	2003
Promoter haplotype combinations for the human PDGFRA gene are associated with risk of neural tube defects. Molecular genetics and metabolism\| PubMed ID: 14741194	2004
Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 14745917	2003
Associations between polymorphisms within the thymidylate synthase gene and spina bifida. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 14745930	2003
Limb deficiency defects, MSX1, and exposure to tobacco smoke. American journal of medical genetics. Part A\| PubMed ID: 14994238	2004
Teratogenicity of valproate conjugates with anticonvulsant activity in mice. Epilepsy research\| PubMed ID: 15013055	2003
Evaluation of the Cited2 gene and risk for spina bifida and congenital heart defects. American journal of medical genetics. Part A\| PubMed ID: 15054851	2004
Evaluation of the jumonji gene and risk for spina bifida and congenital heart defects. American journal of medical genetics. Part A\| PubMed ID: 15057990	2004
Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms. Epidemiology (Cambridge, Mass.)\| PubMed ID: 15127906	2004
Mapping a chromosomal locus for valproic acid-induced exencephaly in mice. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 15170225	2004
Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos. Neurochemical research\| PubMed ID: 15176467	2004
Gene-nutrient interactions: importance of folates and retinoids during early embryogenesis. Toxicology and applied pharmacology\| PubMed ID: 15236946	2004
Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 15259034	2004
Folate modulates Hox gene-controlled skeletal phenotypes. Genesis (New York, N.Y. : 2000)\| PubMed ID: 15282741	2004
Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 15305303	2004
Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 15523664	2004
Epidemiologic study on HFE C282Y mutation in Azerbaijan. European journal of haematology\| PubMed ID: 15654913	2005
Investigations into the etiology of neural tube defects. Birth defects research. Part C, Embryo today : reviews\| PubMed ID: 15662706	2004
Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies. Toxicology and applied pharmacology\| PubMed ID: 15694460	2005
Renal tubular reabsorption of folate mediated by folate binding protein 1. Journal of the American Society of Nephrology : JASN\| PubMed ID: 15703271	2005
Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis. Cancer research\| PubMed ID: 15705887	2005
Reduced folate carrier gene is a risk factor for neural tube defects in a Chinese population. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 15799025	2005
Role of Folbp1 in the regional regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies. American journal of medical genetics. Part C, Seminars in medical genetics\| PubMed ID: 15800851	2005
Are the betaine-homocysteine methyltransferase (BHMT and BHMT2) genes risk factors for spina bifida and orofacial clefts? American journal of medical genetics. Part A\| PubMed ID: 15887275	2005
Epidemiologic characteristics of anophthalmia and bilateral microphthalmia among 2.5 million births in California, 1989-1997. American journal of medical genetics. Part A\| PubMed ID: 16007635	2005
Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial defects and congenital heart defects in China. Annals of epidemiology\| PubMed ID: 16019224	2006
Genetic variation in the proto-oncogene SKI and risk for orofacial clefting. Molecular genetics and metabolism\| PubMed ID: 16054854	2005
Genes encoding catalytic subunits of protein kinase A and risk of spina bifida. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 16080189	2005
Variation in IRF6 contributes to nonsyndromic cleft lip and palate. American journal of medical genetics. Part A\| PubMed ID: 16096995	2005
Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes. American journal of medical genetics. Part A\| PubMed ID: 16100725	2005
Maternal smoking, genetic variation of glutathione s-transferases, and risk for orofacial clefts. Epidemiology (Cambridge, Mass.)\| PubMed ID: 16135950	2005
Valproic acid-induced skeletal malformations: associated gene expression cascades. Pharmacogenetics and genomics\| PubMed ID: 16220111	2005
Spontaneous neural tube defects in splotch mice supplemented with selected micronutrients. Toxicology and applied pharmacology\| PubMed ID: 16226775	2006
A known functional polymorphism (Ile120Val) of the human PCMT1 gene and risk of spina bifida. Molecular genetics and metabolism\| PubMed ID: 16256389	2006
Endothelial nitric oxide synthase (NOS3) genetic variants, maternal smoking, vitamin use, and risk of human orofacial clefts. American journal of epidemiology\| PubMed ID: 16269583	2005
Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China. American journal of medical genetics. Part A\| PubMed ID: 16470725	2006
3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer research\| PubMed ID: 16489053	2006
Myo-inositol enhances teratogenicity of valproic acid in the mouse. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 16511884	2006
Phosphatidylethanolamine N-methyltransferase (PEMT) gene polymorphisms and risk of spina bifida. American journal of medical genetics. Part A\| PubMed ID: 16523512	2006
Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. Neurotoxicology\| PubMed ID: 16620997	2006
Nutrient effects upon embryogenesis: folate, vitamin A and iodine. NestlÃ© Nutrition workshop series. Paediatric programme\| PubMed ID: 16632927	2005
Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug. Neuropharmacology\| PubMed ID: 16890251	2006
Neural tube defects and folate: case far from closed. Nature reviews. Neuroscience\| PubMed ID: 16924261	2006
Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. The Journal of nutritional biochemistry\| PubMed ID: 16963246	2007
Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide. Epilepsy research\| PubMed ID: 16997532	2007
Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure ... American journal of medical genetics. Part A\| PubMed ID: 17036337	2006
Another key role for the cardiac neural crest in heart development. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17098821	2007
Screening for novel PAX3 polymorphisms and risks of spina bifida. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 17149730	2007
Infant C677T MTHFR polymorphism and severe mental retardation. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 17149733	2007
CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population. BMC medicine\| PubMed ID: 17184542	2006
Fetal and maternal MTHFR C677T genotype, maternal folate intake and the risk of nonsyndromic oral clefts. American journal of medical genetics. Part A\| PubMed ID: 17219389	2007
Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 17286298	2007
Association between CFL1 gene polymorphisms and spina bifida risk in a California population. BMC medical genetics\| PubMed ID: 17352815	2007
A new partner for the international knockout mouse consortium. Cell\| PubMed ID: 17448981	2007
Maternal smoking during early pregnancy, GSTP1 and EPHX1 variants, and risk of isolated orofacial clefts. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association\| PubMed ID: 17608547	2007
Nutrient intakes in women and risks of anophthalmia and microphthalmia in their offspring. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 17847120	2007
Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. Journal of medicinal chemistry\| PubMed ID: 17994680	2007
Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube. Human molecular genetics\| PubMed ID: 18003640	2008
Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity. BMC developmental biology\| PubMed ID: 18028541	2007
Importance of folate-homocysteine homeostasis during early embryonic development. Clinical chemistry and laboratory medicine : CCLM / FESCC\| PubMed ID: 18067451	2007
Reproductive consequences of oral arsenate exposure during pregnancy in a mouse model. Birth defects research. Part B, Developmental and reproductive toxicology\| PubMed ID: 18186108	2008
Embryonic development in the reduced folate carrier knockout mouse is modulated by maternal folate supplementation. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 18383508	2008
Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. BMC genomics\| PubMed ID: 18400109	2008
Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid. Epilepsia\| PubMed ID: 18435754	2008
Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 18553462	2008
State of the art in developmental toxicity screening methods and a way forward: a meeting report addressing embryonic stem cells, whole embryo culture, and zebrafish. Birth defects research. Part B, Developmental and reproductive toxicology\| PubMed ID: 18702117	2008
Gene-nutrient interactions: importance of folic acid and vitamin B12 during early embryogenesis. Food and nutrition bulletin\| PubMed ID: 18709884	2008
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome research\| PubMed ID: 18799693	2008
Autoantibodies to folate receptor during pregnancy and neural tube defect risk. Journal of reproductive immunology\| PubMed ID: 18804286	2008
Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer. The Journal of nutritional biochemistry\| PubMed ID: 18926688	2009
Mid-pregnancy cotinine and risks of orofacial clefts and neural tube defects. The Journal of pediatrics\| PubMed ID: 18990410	2009
A cannabinoid analogue of Delta9-tetrahydrocannabinol disrupts neural development in chick. Birth defects research. Part B, Developmental and reproductive toxicology\| PubMed ID: 19040278	2008
Genetic polymorphisms in the thioredoxin 2 (TXN2) gene and risk for spina bifida. American journal of medical genetics. Part A\| PubMed ID: 19165900	2009
Regulation of folate receptor 1 gene expression in the visceral endoderm. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 19180647	2009
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 19204075	2009
Biomarkers of exposure to combustion by-products in a human population in Shanxi, China. Journal of exposure science & environmental epidemiology\| PubMed ID: 19277067	2010
Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid. Journal of medicinal chemistry\| PubMed ID: 19296679	2009
Novel mutations in VANGL1 in neural tube defects. Human mutation\| PubMed ID: 19319979	2009
Arsenate-induced maternal glucose intolerance and neural tube defects in a mouse model. Toxicology and applied pharmacology\| PubMed ID: 19446573	2009
Transcriptional regulation of the novel Toll-like receptor Tlr13. The Journal of biological chemistry\| PubMed ID: 19487701	2009
118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects. BMC medical genetics\| PubMed ID: 19493349	2009
Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): I. Obstetrical complications and change in seizure frequency: Report of the Quality Standards Subcomm... Epilepsia\| PubMed ID: 19496807	2009
Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeuti... Epilepsia\| PubMed ID: 19507301	2009
Management issues for women with epilepsy--focus on pregnancy (an evidence-based review): III. Vitamin K, folic acid, blood levels, and breast-feeding: Report of the Quality Standards Subcom... Epilepsia\| PubMed ID: 19507305	2009
Choline and risk of neural tube defects in a folate-fortified population. Epidemiology (Cambridge, Mass.)\| PubMed ID: 19593156	2009
Whole genome microarray analysis, from neonatal blood cards. BMC genetics\| PubMed ID: 19624846	2009
Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate. Pediatric research\| PubMed ID: 19668105	2009
Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative. Epilepsia\| PubMed ID: 19674061	2010
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nature cell biology\| PubMed ID: 19767740	2009
Autoantibodies to folate receptor alpha during early pregnancy and risk of oral clefts in Denmark. Pediatric research\| PubMed ID: 19952865	2010
Novel folate binding protein-1 interactions in embryonic orofacial tissue. Life sciences\| PubMed ID: 20045418	2010
Planar cell polarity pathway genes and risk for spina bifida. American journal of medical genetics. Part A\| PubMed ID: 20101694	2010
HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis. Gastroenterology\| PubMed ID: 20102719	2010
Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid. Neuropharmacology\| PubMed ID: 20230843	2010
High-affinity folate receptor in cardiac neural crest migration: a gene knockdown model using siRNA. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 20235221	2010
Does global hypomethylation contribute to susceptibility to neural tube defects? The American journal of clinical nutrition\| PubMed ID: 20375188	2010
Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide. Journal of medicinal chemistry\| PubMed ID: 20420384	2010
Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. The Journal of clinical investigation\| PubMed ID: 20424322	2010
Teratogenic effects of antiepileptic drugs. Expert review of neurotherapeutics\| PubMed ID: 20518610	2010
Folic acid in early pregnancy: a public health success story. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 20631328	2010
Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid. Epilepsia\| PubMed ID: 20738383	2010
Genes encoding critical transcriptional activators for murine neural tube development and human spina bifida: a case-control study. BMC medical genetics\| PubMed ID: 20932315	2010
Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. The Journal of investigative dermatology\| PubMed ID: 20962855	2011
Folate pathway and nonsyndromic cleft lip and palate. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 21125565	2010
Folate pathway and nonsyndromic cleft lip and palate. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 21254359	2011
A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency. Blood\| PubMed ID: 21346251	2011
Defective sumoylation pathway directs congenital heart disease. Birth defects research. Part A, Clinical and molecular teratology\| PubMed ID: 21563299	2011
Genetic basis of susceptibility to teratogen induced birth defects. American journal of medical genetics. Part C, Seminars in medical genetics\| PubMed ID: 21766441	2011
Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21768370	2011
Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice. Environmental toxicology and pharmacology\| PubMed ID: 21783456	2005
Fuz regulates craniofacial development through tissue specific responses to signaling factors. PloS one\| PubMed ID: 21935430	2011
Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid. Epilepsy & behavior : E&B\| PubMed ID: 21959082	2011
Cannabinoid Receptor 1 Signaling in Embryo Neurodevelopment. Birth defects research. Part B, Developmental and reproductive toxicology\| PubMed ID: 22311661	2012
Maternal Occupational Exposure to Polycyclic Aromatic Hydrocarbons and Gastroschisis among Offspring in the National Birth Defects Prevention Study. Environmental health perspectives\| PubMed ID: 22330681	2012