Arshad Desai

Ludwig Institute for Cancer Research, San Diego

Affiliated withLudwig Institute for Cancer Research, San Diego University of California, San Diego

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2019

Other Publications

Article	Year
The minus end in sight. Current biology : CB\| PubMed ID: 12906817	2003
Centriole assembly requires both centriolar and pericentriolar material proteins. Developmental cell\| PubMed ID: 15572125	2004
Kinetochore-spindle microtubule interactions during mitosis. Current opinion in cell biology\| PubMed ID: 15661517	2005
The CENP-F-like proteins HCP-1 and HCP-2 target CLASP to kinetochores to mediate chromosome segregation. Current biology : CB\| PubMed ID: 15854912	2005
Distinct roles for two C. elegans anillins in the gonad and early embryo. Development (Cambridge, England)\| PubMed ID: 15930113	2005
Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling. The Journal of cell biology\| PubMed ID: 16144904	2005
A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans. The Journal of cell biology\| PubMed ID: 16247027	2005
Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F. The EMBO journal\| PubMed ID: 16252009	2005
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. The Journal of cell biology\| PubMed ID: 16585270	2006
Molecular analysis of mitotic chromosome condensation using a quantitative time-resolved fluorescence microscopy assay. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17005720	2006
An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. The Journal of cell biology\| PubMed ID: 17130285	2006
A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension. Cell\| PubMed ID: 17174893	2006
Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain. Molecular cell\| PubMed ID: 17244537	2007
Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin. The Journal of cell biology\| PubMed ID: 17339379	2007
A role for Rab5 in structuring the endoplasmic reticulum. The Journal of cell biology\| PubMed ID: 17591921	2007
KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates. Molecular biology of the cell\| PubMed ID: 18045986	2008
Expression and imaging of fluorescent proteins in the C. elegans gonad and early embryo. Methods in cell biology\| PubMed ID: 18155464	2008
The wages of CIN. The Journal of cell biology\| PubMed ID: 18283117	2008
SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the gamma-tubulin-mediated addition of centriolar microtubules. The Journal of cell biology\| PubMed ID: 18299348	2008
A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex. Genes & development\| PubMed ID: 18765790	2008
Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches. Molecular biology of the cell\| PubMed ID: 19109417	2009
Structural memory in the contractile ring makes the duration of cytokinesis independent of cell size. Cell\| PubMed ID: 19490897	2009
The hydrolethalus syndrome protein HYLS-1 links core centriole structure to cilia formation. Genes & development\| PubMed ID: 19656802	2009
Analyzing the effects of delaying aster separation on furrow formation during cytokinesis in the Caenorhabditis elegans embryo. Molecular biology of the cell\| PubMed ID: 19889842	2010
Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. Genes & development\| PubMed ID: 20439434	2010
A kinetochore-independent mechanism drives anaphase chromosome separation during acentrosomal meiosis. Nature cell biology\| PubMed ID: 20729837	2010
A PSHaver for centromeric histones. Molecular cell\| PubMed ID: 21070962	2010
The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly. The Journal of cell biology\| PubMed ID: 21464231	2011
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell\| PubMed ID: 21529718	2011
Uncoordinated loss of chromatid cohesion is a common outcome of extended metaphase arrest. PloS one\| PubMed ID: 21829677	2011
Acute drug treatment in the early C. elegans embryo. PloS one\| PubMed ID: 21935434	2011
Rapid de novo centromere formation occurs independently of heterochromatin protein 1 in C. elegans embryos. Current biology : CB\| PubMed ID: 22018540	2011
Affinity purification of protein complexes in C. elegans. Methods in cell biology\| PubMed ID: 22118282	2011
Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates. Cell\| PubMed ID: 22118461	2011
Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. The Journal of cell biology\| PubMed ID: 22331849	2012
An inverse relationship to germline transcription defines centromeric chromatin in C. elegans. Nature\| PubMed ID: 22495302	2012
Hierarchical assembly of the eggshell and permeability barrier in C. elegans. The Journal of cell biology\| PubMed ID: 22908315	2012
What the hec is up with mouse oocyte meiosis? Developmental cell\| PubMed ID: 23597481	2013
Tension sensing by Aurora B kinase is independent of survivin-based centromere localization. Nature\| PubMed ID: 23604256	2013
Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly. Developmental cell\| PubMed ID: 23673331	2013
A two-step mechanism for epigenetic specification of centromere identity and function. Nature cell biology\| PubMed ID: 23873148	2013
A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis. Developmental cell\| PubMed ID: 24012485	2013
Dominant Mutations in S. cerevisiae PMS1 Identify the Mlh1-Pms1 Endonuclease Active Site and an Exonuclease 1-Independent Mismatch Repair Pathway. PLoS genetics\| PubMed ID: 24204293	2013
The midbody ring scaffolds the abscission machinery in the absence of midbody microtubules. The Journal of cell biology\| PubMed ID: 24217623	2013
Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation. Science (New York, N.Y.)\| PubMed ID: 24231804	2013
Meiotic double-strand breaks uncover and protect against mitotic errors in the C. elegans germline. Current biology : CB\| PubMed ID: 24239117	2013
Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes & development\| PubMed ID: 24449268	2014
Linked in: formation and regulation of microtubule attachments during chromosome segregation. Current opinion in cell biology\| PubMed ID: 24529253	2014
A Bub1-Mad1 interaction targets the Mad1-Mad2 complex to unattached kinetochores to initiate the spindle checkpoint. The Journal of cell biology\| PubMed ID: 24567362	2014
Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae. PLoS genetics\| PubMed ID: 24811092	2014
PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. Molecular cell\| PubMed ID: 24981171	2014
A new piece in the kinetochore jigsaw puzzle. The Journal of cell biology\| PubMed ID: 25135931	2014
The outer kinetochore protein KNL-1 contains a defined oligomerization domain in nematodes. Molecular biology of the cell\| PubMed ID: 25411336	2015
The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast. Current biology : CB\| PubMed ID: 25619765	2015
Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors. Molecular biology of the cell\| PubMed ID: 25808490	2015
Separase Cleaves the N-Tail of the CENP-A Related Protein CPAR-1 at the Meiosis I Metaphase-Anaphase Transition in C. elegans. PloS one\| PubMed ID: 25919583	2015
Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4. Science (New York, N.Y.)\| PubMed ID: 25931445	2015
Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans. The Journal of cell biology\| PubMed ID: 25987605	2015
Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition. Oncotarget\| PubMed ID: 26059434	2015
Natural Loss of Mps1 Kinase in Nematodes Uncovers a Role for Polo-like Kinase 1 in Spindle Checkpoint Initiation. Cell reports\| PubMed ID: 26119738	2015
NOCA-1 functions with γ-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans. eLife\| PubMed ID: 26371552	2015
A Cell Biologist's Field Guide to Aurora Kinase Inhibitors. Frontiers in oncology\| PubMed ID: 26732741	2015
A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions. Cell\| PubMed ID: 27020753	2016
A TOGgle for Tension at Kinetochores. Cell\| PubMed ID: 27259144	2016
53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. The Journal of cell biology\| PubMed ID: 27432897	2016
A Nucleoporin Docks Protein Phosphatase 1 to Direct Meiotic Chromosome Segregation and Nuclear Assembly. Developmental cell\| PubMed ID: 27623381	2016
A Molecular View of Kinetochore Assembly and Function. Biology\| PubMed ID: 28125021	2017
How centrioles acquire the ability to reproduce. eLife\| PubMed ID: 28271993	2017
An engineered minimal chromosomal passenger complex reveals a role for INCENP/Sli15 spindle association in chromosome biorientation. The Journal of cell biology\| PubMed ID: 28314741	2017
Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex. Developmental cell\| PubMed ID: 28535376	2017
A toolkit for GFP-mediated tissue-specific protein degradation in . Development (Cambridge, England)\| PubMed ID: 28619826	2017
Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System. Developmental cell\| PubMed ID: 28633018	2017
Kinetochores accelerate or delay APC/C activation by directing Cdc20 to opposing fates. Genes & development\| PubMed ID: 28698300	2017
Channel Nucleoporins Recruit PLK-1 to Nuclear Pore Complexes to Direct Nuclear Envelope Breakdown in C. elegans. Developmental cell\| PubMed ID: 29065307	2017
Taming the Beast: Control of APC/C-Dependent Destruction. Cold Spring Harbor symposia on quantitative biology\| PubMed ID: 29133301	2017
Meiosis: The Origins of Bias. Current biology : CB\| PubMed ID: 29257963	2017
Cdc73 suppresses genome instability by mediating telomere homeostasis. PLoS genetics\| PubMed ID: 29320491	2018
Employing the one-cell C. elegans embryo to study cell division processes. Methods in cell biology\| PubMed ID: 29804670	2018
Analyzing the micromechanics of the cell division apparatus. Methods in cell biology\| PubMed ID: 29957203	2018
A positive-feedback-based mechanism for constriction rate acceleration during cytokinesis in . eLife\| PubMed ID: 29963981	2018
CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia. eLife\| PubMed ID: 29989548	2018
Promoting an "Auteur Theory" for Young Scientists: Preserving Excitement and Creativity …. BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 30238592	2018
CFI-400945 is not a selective cellular PLK4 inhibitor. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30377272	2018
The Kinetochore-Microtubule Coupling Machinery Is Repurposed in Sensory Nervous System Morphogenesis. Developmental cell\| PubMed ID: 30827898	2019
A high-content imaging approach to profile embryonic development. Development (Cambridge, England)\| PubMed ID: 30890570	2019
Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nature chemical biology\| PubMed ID: 30911178	2019
Ancestral roles of the Fam20C family of secreted protein kinases revealed in . The Journal of cell biology\| PubMed ID: 31541016	2019