Alexandre Harari

Department of Oncology UNIL CHUV, University of Lausanne

Affiliated withUniversity of Lausanne Centre Hospitalier Universitaire Vaudois

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2019

Other Publications

Article	Year
Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy. The Journal of clinical investigation\| PubMed ID: 11877476	2002
Transepithelial transport of HIV-1 by M cells is receptor-mediated. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12093918	2002
Analysis of HIV-1- and CMV-specific memory CD4 T-cell responses during primary and chronic infection. Blood\| PubMed ID: 12149221	2002
Antiviral memory T cell responses: correlation with protective immunity and implication for vaccine development. Advances in experimental medicine and biology\| PubMed ID: 12405200	2002
Distribution and functional analysis of memory antiviral CD8 T cell responses in HIV-1 and cytomegalovirus infections. European journal of immunology\| PubMed ID: 12516570	2002
Cytomegalovirus (CMV)-specific cellular immune responses. Human immunology\| PubMed ID: 15172450	2004
Phenotypic heterogeneity of antigen-specific CD4 T cells under different conditions of antigen persistence and antigen load. European journal of immunology\| PubMed ID: 15484193	2004
HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15872023	2005
Understanding what makes a good versus a bad vaccine. European journal of immunology\| PubMed ID: 16106373	2005
Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases. Nature reviews. Immunology\| PubMed ID: 16622477	2006
Functional signatures of protective antiviral T-cell immunity in human virus infections. Immunological reviews\| PubMed ID: 16824132	2006
Functional patterns of HIV-1-specific CD4 T-cell responses in children are influenced by the extent of virus suppression and exposure. AIDS (London, England)\| PubMed ID: 17148964	2007
Functional and phenotypic characterization of tetanus toxoid-specific human CD4+ T cells following re-immunization. European journal of immunology\| PubMed ID: 17372991	2007
Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses. The Journal of experimental medicine\| PubMed ID: 17535971	2007
Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17911249	2007
HIV-1-specific immune response. Advances in pharmacology (San Diego, Calif.)\| PubMed ID: 18086409	2008
An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses. The Journal of experimental medicine\| PubMed ID: 18195071	2008
Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure. Journal of virology\| PubMed ID: 19176626	2009
Comparison of human and rhesus macaque T-cell responses elicited by boosting with NYVAC encoding human immunodeficiency virus type 1 clade C immunogens. Journal of virology\| PubMed ID: 19321612	2009
Role of HIV-1-specific CD4 T cells. Current opinion in HIV and AIDS\| PubMed ID: 19372779	2006
Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expres... Journal of virology\| PubMed ID: 20130059	2010
Dominant TNF-Î±+ Mycobacterium tuberculosis-specific CD4+ T cell responses discriminate between latent infection and active disease. Nature medicine\| PubMed ID: 21336285	2011
Early and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-term non-progressors. PloS one\| PubMed ID: 21483676	2011
Large TCR diversity of virus-specific CD8 T cells provides the mechanistic basis for massive TCR renewal after antigen exposure. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21555537	2011
DNA/NYVAC vaccine regimen induces HIV-specific CD4 and CD8 T-cell responses in intestinal mucosa. Journal of virology\| PubMed ID: 21775454	2011
Functional avidity: a measure to predict the efficacy of effector T cells? Clinical & developmental immunology\| PubMed ID: 23227083	2012
Mycobacterium tuberculosis-specific CD8+ T cells are functionally and phenotypically different between latent infection and active disease. European journal of immunology\| PubMed ID: 23456989	2013
CD160-associated CD8 T-cell functional impairment is independent of PD-1 expression. PLoS pathogens\| PubMed ID: 25255144	2014
Combined use of Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 25362202	2015
Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins. Journal of virology\| PubMed ID: 25609807	2015
Personalized approaches to active immunotherapy in cancer. Biochimica et biophysica acta\| PubMed ID: 26241169	2016
Neoantigen-based cancer immunotherapy. Annals of translational medicine\| PubMed ID: 27563649	2016
Cancer Vaccines in Ovarian Cancer: How Can We Improve? Biomedicines\| PubMed ID: 28536377	2016
Sensitive and frequent identification of high avidity neo-epitope specific CD8 T cells in immunotherapy-naive ovarian cancer. Nature communications\| PubMed ID: 29545564	2018
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer. Science translational medicine\| PubMed ID: 29643231	2018
Computational KIR copy number discovery reveals interaction between inhibitory receptor burden and survival. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing\| PubMed ID: 30864318	2019
Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients. The Journal of experimental medicine\| PubMed ID: 30975896	2019
High-throughput Screening of Human Tumor Antigen-specific CD4 T Cells, Including Neoantigen-reactive T Cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 31015344	2019
A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adeno... Frontiers in immunology\| PubMed ID: 31440238	2019
Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8 T cells. Journal for immunotherapy of cancer\| PubMed ID: 31601268	2019
Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes. Nature biotechnology\| PubMed ID: 31611696	2019
A Phase I/II trial comparing autologous dendritic cell vaccine pulsed either with personalized peptides (PEP-DC) or with tumor lysate (OC-DC) in patients with advanced high-grade ovarian ser... Journal of translational medicine\| PubMed ID: 31771601	2019