James E. Klaunig

School of Public Health, Indiana University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2019

Other Publications

Article	Year
Effects of 2-butoxyethanol on hepatic oxidative damage. Toxicology letters\| PubMed ID: 11738267	2002
Acrylamide-induced cellular transformation. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 11812921	2002
Comparative effects of phthalate monoesters on gap junctional intercellular communication and peroxisome proliferation in rodent and primate hepatocytes. Journal of toxicology and environmental health. Part A\| PubMed ID: 11995694	2002
Mechanisms for the induction of oxidative stress in Syrian hamster embryo cells by acrylonitrile. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 12011484	2002
Mechanisms of 2-butoxyethanol carcinogenicity: studies on Syrian Hamster Embryo (SHE) cell transformation. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 12075109	2002
Morphological transformation and oxidative stress induced by cyanide in Syrian hamster embryo (SHE) cells. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 12151639	2002
Hepatic effects of 2-butoxyethanol in rodents. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 12441370	2002
Minocycline blocks 6-hydroxydopamine-induced neurotoxicity and free radical production in rat cerebellar granule neurons. Life sciences\| PubMed ID: 12551752	2003
PPARalpha agonist-induced rodent tumors: modes of action and human relevance. Critical reviews in toxicology\| PubMed ID: 14727734	2003
The role of oxidative stress in carcinogenesis. Annual review of pharmacology and toxicology\| PubMed ID: 14744246	2004
The effects of ecstasy (MDMA) on rat liver bioenergetics. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine\| PubMed ID: 15231458	2004
Subchronic acrylamide treatment induces a tissue-specific increase in DNA synthesis in the rat. Toxicology letters\| PubMed ID: 15475183	2004
Species differences in the induction of hepatocellular DNA synthesis by diethanolamine. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 16014740	2005
Indinavir impairs endothelial function in healthy HIV-negative men. American heart journal\| PubMed ID: 16290967	2005
Cancer biology and hormesis: commentary. Critical reviews in toxicology\| PubMed ID: 16422395	2005
Mechanisms of acrylamide induced rodent carcinogenesis. Advances in experimental medicine and biology\| PubMed ID: 16438288	2005
Mechanisms of 2-butoxyethanol-induced hemangiosarcomas. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 16675516	2006
Acrylonitrile-induced oxidative DNA damage in rat astrocytes. Environmental and molecular mutagenesis\| PubMed ID: 16917936	2006
PPARalpha and effects of TCE. Environmental health perspectives\| PubMed ID: 17366801	2007
Constitutional polymorphisms of prostate cancer: prognostic and diagnostic implications. Future oncology (London, England)\| PubMed ID: 18041919	2007
Oxidative status in neuroblastoma: a source of stress? Journal of pediatric surgery\| PubMed ID: 18280284	2008
Acrylamide carcinogenicity. Journal of agricultural and food chemistry\| PubMed ID: 18624430	2008
Remembering Benjamin Franklin Trump. Veterinary pathology\| PubMed ID: 18725462	2008
Effect of oral methyl-t-butyl ether (MTBE) on the male mouse reproductive tract and oxidative stress in liver. Reproductive toxicology (Elmsford, N.Y.)\| PubMed ID: 18824092	2008
Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine. Hepatology (Baltimore, Md.)\| PubMed ID: 19434740	2009
Acrylonitrile-induced oxidative stress and oxidative DNA damage in male Sprague-Dawley rats. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 19546159	2009
Oxidative stress and oxidative damage in carcinogenesis. Toxicologic pathology\| PubMed ID: 20019356	2010
Kupffer cells participate in 2-butoxyethanol-induced liver hemangiosarcomas. Toxicology\| PubMed ID: 20153399	2010
Conditional beta-catenin loss in mice promotes chemical hepatocarcinogenesis: role of oxidative stress and platelet-derived growth factor receptor alpha/phosphoinositide 3-kinase signaling. Hepatology (Baltimore, Md.)\| PubMed ID: 20583210	2010
Assessment of gap junctional intercellular communication. Current protocols in toxicology\| PubMed ID: 20941698	2009
Linear low-dose extrapolation for noncancer heath effects is the exception, not the rule. Critical reviews in toxicology\| PubMed ID: 21226629	2011
Effect of different obesogenic diets on pancreatic histology in Ossabaw miniature swine. Pancreas\| PubMed ID: 21240032	2011
Oxidative stress and oxidative damage in chemical carcinogenesis. Toxicology and applied pharmacology\| PubMed ID: 21296097	2011
Dose-related induction of hepatic preneoplastic lesions by diethylnitrosamine in C57BL/6 mice. Toxicologic pathology\| PubMed ID: 21628716	2011
Oxidative stress in chronic liver disease: relationship between peripheral and hepatic measurements. The American journal of the medical sciences\| PubMed ID: 21691193	2011
Mode of Action analysis of perfluorooctanoic acid (PFOA) tumorigenicity and Human Relevance. Reproductive toxicology (Elmsford, N.Y.)\| PubMed ID: 22120428	2012
Alterations in brain structure and function in breast cancer survivors: effect of post-chemotherapy interval and relation to oxidative DNA damage. Breast cancer research and treatment\| PubMed ID: 23263697	2013
Caenorhabditis elegans neuron degeneration and mitochondrial suppression caused by selected environmental chemicals. International journal of biochemistry and molecular biology\| PubMed ID: 24380023	2013
Contribution of environment and genetics to pancreatic cancer susceptibility. PloS one\| PubMed ID: 24651674	2014
Evaluating uncertainty to strengthen epidemiologic data for use in human health risk assessments. Environmental health perspectives\| PubMed ID: 25079138	2014
Development of a cytokine-producing immortalized murine Kupffer cell line. Cytokine\| PubMed ID: 25138015	2014
Mechanism of 1,3-dichloropropene-induced rat liver carcinogenesis. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 25354764	2015
Evaluation of the chronic toxicity and carcinogenicity of perfluorohexanoic acid (PFHxA) in Sprague-Dawley rats. Toxicologic pathology\| PubMed ID: 25377447	2015
Antioxidant vitamin C prevents decline in endothelial function during sitting. Medical science monitor : international medical journal of experimental and clinical research\| PubMed ID: 25848890	2015
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis\| PubMed ID: 26106142	2015
The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling. Carcinogenesis\| PubMed ID: 26106143	2015
Toxicology of decamethylcyclopentasiloxane (D5). Regulatory toxicology and pharmacology : RTP\| PubMed ID: 26111607	2016
Biological relevance of decamethylcyclopentasiloxane (D5) induced rat uterine endometrial adenocarcinoma tumorigenesis: Mode of action and relevance to humans. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 26148665	2016
Mechanistic Investigation of Toxaphene Induced Mouse Liver Tumors. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 26187448	2015
Alkaline Comet Assay for Assessing DNA Damage in Individual Cells. Current protocols in toxicology\| PubMed ID: 26250399	2015
Protective effects of antioxidants on acrylonitrile-induced oxidative stress in female F344 rats. Environmental toxicology\| PubMed ID: 26332274	2016
Cryopreservation of human blood for alkaline and Fpg-modified comet assay. Toxicology mechanisms and methods\| PubMed ID: 26982377	2016
A randomized placebo-controlled pilot study of N-acetylcysteine in youth with autism spectrum disorder. Molecular autism\| PubMed ID: 27103982	2016
Response to Druwe and Burgoon : Re: Druwe, I.L. and Burgoon, L.: revisiting Cohen et al. 2015, Cohen et al. 2014 and Waalkes et al. 2014: a bayesian re-analysis of tumor incidences. Archives of toxicology\| PubMed ID: 27542124	2016
Whither the impending european regulation of presumed endocrine disruptors? Regulatory toxicology and pharmacology : RTP\| PubMed ID: 27615676	2016
Upholding science in health, safety and environmental risk assessments and regulations. Toxicology\| PubMed ID: 27639665	2016
Response to Druwe and Burgoon, 2016 Letter to the Editor in Archives of Toxicology. Archives of toxicology\| PubMed ID: 27830267	2017
Biological relevance of effects following chronic administration of octamethylcyclotetrasiloxane (D4) in Fischer 344 rats. Toxicology letters\| PubMed ID: 28109826	2017
Toxaphene-induced mouse liver tumorigenesis is mediated by the constitutive androstane receptor. Journal of applied toxicology : JAT\| PubMed ID: 28218408	2017
Investigation of the mechanism of triclosan induced mouse liver tumors. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 28267557	2017
Induction of endogenous retroelements as a potential mechanism for mouse-specific drug-induced carcinogenicity. PloS one\| PubMed ID: 28472135	2017
Comments on the safety assessment of decamethylcyclopentasiloxane (D5) published in regulatory toxicology and pharmacology, 2017, 83:117-118. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 28780200	2017
Human relevance of rodent liver tumors: Key insights from a Toxicology Forum workshop on nongenotoxic modes of action. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 29113941	2018
The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions. Archives of toxicology\| PubMed ID: 29197930	2018
Autophagy plays a protective role in Mn-induced toxicity in PC12 cells. Toxicology\| PubMed ID: 29222055	2018
Effect of polyhexamethylene biguanide on rat liver. Toxicology letters\| PubMed ID: 29305328	2018
Obfuscating transparency? Regulatory toxicology and pharmacology : RTP\| PubMed ID: 30017904	2018
Role of xenobiotics in the induction and progression of fatty liver disease. Toxicology research\| PubMed ID: 30090613	2018
Modulation of xenobiotic nuclear receptors in high-fat diet induced non-alcoholic fatty liver disease. Toxicology\| PubMed ID: 30120929	2018
Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models. PloS one\| PubMed ID: 30212461	2018
A simple automated method for continuous fieldwise measurement of microvascular hemodynamics. Microvascular research\| PubMed ID: 30502365	2019
Editorial. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 30642615	2019
The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice. Toxicology\| PubMed ID: 30711707	2019
Oxidative Stress and Cancer. Current pharmaceutical design\| PubMed ID: 30767733	2018
Icariin protects rotenone-induced neurotoxicity through induction of SIRT3. Toxicology and applied pharmacology\| PubMed ID: 31251943	2019