Susan Clark

Epigenetics Group, Garvan Institute of Medical Research

Affiliated withGarvan Institute of Medical Research University of NSW

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 75	2011

Other Publications

Article	Year
Hypermethylation of the inhibin alpha-subunit gene in prostate carcinoma. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 11818495	2002
Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells. Oncogene\| PubMed ID: 11850822	2002
"Tinkering" with the components of health. The Journal of school health\| PubMed ID: 11865799	2002
DNA methylation analysis in mammalian cells. Methods (San Diego, Calif.)\| PubMed ID: 12095265	2002
Identification and resolution of artifacts in bisulfite sequencing. Methods (San Diego, Calif.)\| PubMed ID: 12095266	2002
Methylation sequencing from limiting DNA: embryonic, fixed, and microdissected cells. Methods (San Diego, Calif.)\| PubMed ID: 12095267	2002
Conversion-specific detection of DNA methylation using real-time polymerase chain reaction (ConLight-MSP) to avoid false positives. Methods (San Diego, Calif.)\| PubMed ID: 12095268	2002
DNA methylation and gene silencing in cancer: which is the guilty party? Oncogene\| PubMed ID: 12154400	2002
DNA methylation changes in leukaemia. Seminars in cancer biology\| PubMed ID: 12191634	2002
Confirmation of phenylbutazone residues in bovine kidney by liquid chromatography/mass spectrometry. Journal of AOAC International\| PubMed ID: 12374396	2002
A question-and-answer approach to drug education. The Journal of school health\| PubMed ID: 12389376	2002
Interlaboratory comparison of methods for the determination of incurred tilmicosin residues in bovine liver. Journal of AOAC International\| PubMed ID: 12477187	2002
Stepwise progression of familial adenomatous polyposis-associated desmoid precursor lesions demonstrated by a novel CT scoring system. Diseases of the colon and rectum\| PubMed ID: 12682541	2003
Bisulfite methylation analysis of tumor suppressor genes in prostate cancer from fresh and archival tissue samples. Methods in molecular medicine\| PubMed ID: 12725123	2003
Health professionals helping the community. The Journal of school health\| PubMed ID: 14513632	2003
Alterations in the p16(INK4a) and p53 tumor suppressor genes of hTERT-immortalized human fibroblasts. Oncogene\| PubMed ID: 14743210	2004
Spirituality and sexuality: compatible components for optimal health. The Journal of school health\| PubMed ID: 15022373	2004
Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells. Cancer research\| PubMed ID: 15172996	2004
Alimentary tract surgery in the nonagenarian: elective vs. emergent operations. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract\| PubMed ID: 15239987	2004
High-dose tamoxifen and sulindac as first-line treatment for desmoid tumors. Cancer\| PubMed ID: 15274082	2004
Incidence of low free T4 values in premature infants as determined by direct equilibrium dialysis. Journal of perinatology : official journal of the California Perinatal Association\| PubMed ID: 15306825	2004
Evaluation of decontamination procedures used in primary care. Nursing times\| PubMed ID: 15478836	2004
All-optical switching in rubidium vapor. Science (New York, N.Y.)\| PubMed ID: 15860622	2005
Developing empathy for hearing-impaired students: can you hear what I hear? The Journal of school health\| PubMed ID: 15929597	2005
Confirmation of sulfamethazine, sulfathiazole, and sulfadimethoxine residues in condensed milk and soft-cheese products by liquid chromatography/tandem mass spectrometry. Journal of AOAC International\| PubMed ID: 16001847	2005
Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy. Oncogene\| PubMed ID: 16007128	2005
Headloop suppression PCR and its application to selective amplification of methylated DNA sequences. Nucleic acids research\| PubMed ID: 16091627	2005
The biochemistry of antioxidants revisited. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition\| PubMed ID: 16214960	2002
Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation. PLoS genetics\| PubMed ID: 16477312	2006
Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band. Nature genetics\| PubMed ID: 16642018	2006
Current ideas in desmoid tumours. Familial cancer\| PubMed ID: 16998673	2006
The effect of link nurses on hospital readmission rates. Nursing times\| PubMed ID: 17066881	2006
Telomere-driven karyotypic complexity concurs with p16INK4a inactivation in TP53-competent immortal endothelial cells. Cancer research\| PubMed ID: 17108106	2006
Exercise in the heat: effect of fluid ingestion on blood-brain barrier permeability. Medicine and science in sports and exercise\| PubMed ID: 17146318	2006
Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer. Gastroenterology\| PubMed ID: 17258725	2007
Perception of voice in the transgender client. Journal of voice : official journal of the Voice Foundation\| PubMed ID: 17400427	2008
DNA methylation: bisulphite modification and analysis. Nature protocols\| PubMed ID: 17406479	2006
The impact of technical factors on outcome of restorative proctocolectomy for familial adenomatous polyposis. Diseases of the colon and rectum\| PubMed ID: 17464542	2007
The effect of restorative proctocolectomy on sexual function, urinary function, fertility, pregnancy and delivery: a systematic review. Diseases of the colon and rectum\| PubMed ID: 17588223	2007
Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis. Human molecular genetics\| PubMed ID: 17613553	2007
Quantum computers based on electron spins controlled by ultrafast off-resonant single optical pulses. Physical review letters\| PubMed ID: 17678343	2007
Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements. Nucleic acids research\| PubMed ID: 17855397	2007
Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer. Cancer research\| PubMed ID: 17909015	2007
Enhancing health literacy through accessing health information, products, and services: an exercise for children and adolescents. The Journal of school health\| PubMed ID: 17970869	2007
Bisulphite differential denaturation PCR for analysis of DNA methylation. Epigenetics : official journal of the DNA Methylation Society\| PubMed ID: 17998815	2006
Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis. Cancer research\| PubMed ID: 18089780	2007
DNA methylation changes in ovarian cancer: implications for early diagnosis, prognosis and treatment. Gynecologic oncology\| PubMed ID: 18234305	2008
Iron deficiency anemia. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition\| PubMed ID: 18390780	2008
This is your future: a case study approach to foster health literacy. The Journal of school health\| PubMed ID: 18489469	2008
Determination and confirmation of melamine residues in catfish, trout, tilapia, salmon, and shrimp by liquid chromatography with tandem mass spectrometry. Journal of agricultural and food chemistry\| PubMed ID: 18494486	2008
Epigenetic markers of ovarian cancer. Advances in experimental medicine and biology\| PubMed ID: 18546617	2008
Persistent perineal sinus after ileoanal pouch excision in inflammatory bowel diseases: incidence, risk factors, and clinical course. Diseases of the colon and rectum\| PubMed ID: 18626712	2008
The risk of oral contraceptives in the etiology of inflammatory bowel disease: a meta-analysis. The American journal of gastroenterology\| PubMed ID: 18684177	2008
Breast cancer epigenetics: normal human mammary epithelial cells as a model system. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 18716754	2008
Climate warming, marine protected areas and the ocean-scale integrity of coral reef ecosystems. PloS one\| PubMed ID: 18728776	2008
Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice. Human molecular genetics\| PubMed ID: 18782851	2008
Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice. BMC physiology\| PubMed ID: 18793434	2008
The comparative incidence of reported concussions presenting for follow-up management in South African Rugby Union. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine\| PubMed ID: 18806547	2008
Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours. Clinical endocrinology\| PubMed ID: 19067722	2009
Guide to endoscopy of the ileo-anal pouch following restorative proctocolectomy with ileal pouch-anal anastomosis; indications, technique, and management of common findings. Inflammatory bowel diseases\| PubMed ID: 19180580	2009
Iron deficiency anemia: diagnosis and management. Current opinion in gastroenterology\| PubMed ID: 19262200	2009
Features of duodenal cancer in patients with familial adenomatous polyposis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 19281862	2009
Multiresidue method for the triphenylmethane dyes in fish: Malachite green, crystal (gentian) violet, and brilliant green. Analytica chimica acta\| PubMed ID: 19286041	2009
Fecal coliform testing to identify effective antibiotic therapies for patients with antibiotic-resistant pouchitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 19418603	2009
Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning. Human molecular genetics\| PubMed ID: 19477956	2009
Symptomatic polyposis in a 4-year-old: the exception proves the rule. Journal of paediatrics and child health\| PubMed ID: 19493128	2009
Incidence and short-term implications of prepouch ileitis following restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. Diseases of the colon and rectum\| PubMed ID: 19502851	2009
A mitotic recombination map proximal to the APC locus on chromosome 5q and assessment of influences on colorectal cancer risk. BMC medical genetics\| PubMed ID: 19515250	2009
Osteoporosis in patients over 50 years of age following restorative proctocolectomy for ulcerative colitis: is DXA screening warranted? Inflammatory bowel diseases\| PubMed ID: 19591132	2010
Ultrafast optical spin echo for electron spins in semiconductors. Physical review letters\| PubMed ID: 19659047	2009
The role of pouch compliance measurement in the management of pouch dysfunction. International journal of colorectal disease\| PubMed ID: 19924421	2010
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity. Nature cell biology\| PubMed ID: 20173741	2010
A review of weight loss following Roux-en-Y gastric bypass vs restrictive bariatric surgery: impact on adiponectin and insulin. Obesity surgery\| PubMed ID: 20177811	2010
Eicosapentaenoic acid reduces rectal polyp number and size in familial adenomatous polyposis. Gut\| PubMed ID: 20348368	2010
Familial adenomatous polyposis (FAP) and gender. Does gender influence the genetic transmission of FAP? Familial cancer\| PubMed ID: 20411341	2010
Repitools: an R package for the analysis of enrichment-based epigenomic data. Bioinformatics (Oxford, England)\| PubMed ID: 20457667	2010
Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer. International journal of cancer. Journal international du cancer\| PubMed ID: 20473948	2011
The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing. Annals of surgery\| PubMed ID: 20562611	2010
A prospective study of MR enterography versus capsule endoscopy for the surveillance of adult patients with Peutz-Jeghers syndrome. AJR. American journal of roentgenology\| PubMed ID: 20566803	2010
Defining responsibilities of simulated patients in medical education. Simulation in healthcare : journal of the Society for Simulation in Healthcare\| PubMed ID: 20651478	2010
Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy. Journal of the American College of Cardiology\| PubMed ID: 20688032	2010
Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias. Epigenetics : official journal of the DNA Methylation Society\| PubMed ID: 20818161	2011
Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5. Gut\| PubMed ID: 20926645	2010
Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation. Genome research\| PubMed ID: 21045081	2010
Colorectal cancer: no longer the issue in familial adenomatous polyposis? Familial cancer\| PubMed ID: 21052851	2011
Epigenetic deregulation across chromosome 2q14.2 differentiates normal from prostate cancer and provides a regional panel of novel DNA methylation cancer biomarkers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 21098650	2011
Mucosectomy with handsewn anastomosis reduces the risk of adenoma formation in the anorectal segment after restorative proctocolectomy for familial adenomatous polyposis. Annals of surgery\| PubMed ID: 21173697	2011
Discovery pipeline for epigenetically deregulated miRNAs in cancer: integration of primary miRNA transcription. BMC genomics\| PubMed ID: 21255435	2011
Analysis of veterinary drugs and metabolites in milk using quadrupole time-of-flight liquid chromatography-mass spectrometry. Journal of agricultural and food chemistry\| PubMed ID: 21284383	2011
CD154-CD40 interactions in the control of murine B cell hematopoiesis. Journal of leukocyte biology\| PubMed ID: 21330346	2011
College and university environmental programs as a policy problem (part 2): strategies for improvement. Environmental management\| PubMed ID: 21359524	2011
College and university environmental programs as a policy problem (part 1): integrating knowledge, education, and action for a better world? Environmental management\| PubMed ID: 21359525	2011
Optimization and validation of a multiclass screening and confirmation method for drug residues in milk using high-performance liquid chromatography/tandem mass spectrometry. Journal of AOAC International\| PubMed ID: 21563671	2011
Protocol matters: which methylome are you actually studying? Epigenomics\| PubMed ID: 21566704	2010
Epigenetics in prostate cancer: biologic and clinical relevance. European urology\| PubMed ID: 21719191	2011
Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer. Genome research\| PubMed ID: 21788347	2012
Lineage specific methylation of the Elf5 promoter in mammary epithelial cells. Stem cells (Dayton, Ohio)\| PubMed ID: 21823211	2011
Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells. Epigenetics : official journal of the DNA Methylation Society\| PubMed ID: 21852760	2011
Nurse practitioner management of chronic musculoskeletal pain: a chart review. The Nurse practitioner\| PubMed ID: 21857215	2011
Key challenges in simulated patient programs: an international comparative case study. BMC medical education\| PubMed ID: 21943295	2011
miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA. The EMBO journal\| PubMed ID: 21964070	2011
Human gut-specific homeostatic dendritic cells are generated from blood precursors by the gut microenvironment. Inflammatory bowel diseases\| PubMed ID: 21987473	2011
Impact of the genome on the epigenome is manifested in DNA methylation patterns of imprinted regions in monozygotic and dizygotic twins. PloS one\| PubMed ID: 21991322	2011
The development of a social morbidity score in patients with chronic ulcerative colitis as a potential guide to treatment. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland\| PubMed ID: 22053990	2011
Prognostic and diagnostic significance of DNA methylation patterns in high grade serous ovarian cancer. Gynecologic oncology\| PubMed ID: 22115852	2012
Epigenetic architecture and miRNA: reciprocal regulators. Epigenomics\| PubMed ID: 22122085	2010
MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma. PloS one\| PubMed ID: 22132151	2011
Integrative genome-wide expression and promoter DNA methylation profiling identifies a potential novel panel of ovarian cancer epigenetic biomarkers. Cancer letters\| PubMed ID: 22155104	2011
A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts. Gut\| PubMed ID: 22287596	2012