Maureen Gannon

Maureen Gannon

Department of Molecular Physiology and Biophysics, Vanderbilt University

Affiliated withVanderbilt UniversityDepartment of Veterans Affairs Tennessee ValleyVanderbilt University Medical Center

Research Area

Biography

Maureen Gannon, PhD is Associate Dean for Faculty Development and Professor of Medicine at Vanderbilt University Medical Center with secondary appointments in the Departments of Molecular Physiology & Biophysics and Cell & Developmental Biology at Vanderbilt University. She received her undergraduate degree from Molloy College and her Master’s Degree from Adelphi University, both on Long Island in NY. She received her PhD in Cell Biology and Anatomy from Cornell University.

Dr. Gannon is a member of the Executive Committee for the Vanderbilt Diabetes Center. She is also very active in the American Diabetes Association, having served on several national committees, including two years as chair of the planning committee for the association’s annual scientific conference, and one year as Chair of the Islet Biology Professional Interest Group. She is currently a senior associate editor for Diabetes, the premier scientific research journal of the American Diabetes Association.

The research in Dr. Gannon’s lab is focused on factors that regulate the number of insulin-producing cells during embryonic development and in response to pregnancy, obesity, and aging. Her research has implications for the treatment of Type 1 diabetes, Type 2 diabetes and gestational diabetes. The Gannon lab has identified genes that regulate the number of insulin cells an individual is born with and has discovered pathways that can increase the number of insulin cells in the adult pancreas.

Dr. Gannon’s research has been funded by grants from the National Institutes of Health, Juvenile Diabetes Research Foundation, American Diabetes Association, and the Veterans Administration. She has presented her research at conferences in the US, Europe, Asia, and the Middle East. Dr. Gannon is very active in training and mentoring undergraduates, graduate students and junior faculty. She lives in Nashville, TN with her husband and son. In her spare time she performs in Celtic singing and Irish Step Dancing, having performed at the Ryman Auditorium with The Chieftains, onstage at the Grand Old Opry, and at TPAC. She also sings in her church music group and volunteers with her son’s boy scout troop.

JoVE Journal Publications

ArticleTotal : 2
Year
Analysis of Non-Human Primate Pancreatic Islet Oxygen Consumption
Publication title

Cited by 1

2019
2024

Other Publications

Article
Year
PDX:PBX complexes are required for normal proliferation of pancreatic cells during development.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 11158595

2001
2002
2002
2002
The role of pdx1 and HNF6 in proliferation and differentiation of endocrine precursors.

Diabetes/metabolism research and reviews| PubMed ID: 15037986

2004
2004
2004
2005
2006
The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass.

Molecular endocrinology (Baltimore, Md.)| PubMed ID: 16556734

2006
Characterization of diabetic nephropathy in a transgenic model of hypoinsulinemic diabetes.

American journal of physiology. Renal physiology| PubMed ID: 16705146

2006
2006
2006
2006
2007
2007
2007
2007
2008
2008
2008
2009
2009
Bioluminescence imaging in mouse models quantifies beta cell mass in the pancreas and after islet transplantation.

Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging| PubMed ID: 19548035

2010
Pancreas cell fate.

Birth defects research. Part C, Embryo today : reviews| PubMed ID: 19750517

2009
2009
2010
2010
2010
2010
Diet-induced impaired glucose tolerance and gestational diabetes in the dog.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 21088210

2011
2011
Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21876171

2011
2012
2012
Differential regulation of embryonic and adult β cell replication.

Cell cycle (Georgetown, Tex.)| PubMed ID: 22659844

2012
Inactivation of the dual Bmp/Wnt inhibitor Sostdc1 enhances pancreatic islet function.

American journal of physiology. Endocrinology and metabolism| PubMed ID: 22829579

2012
The skeletal site-specific role of connective tissue growth factor in prenatal osteogenesis.

Developmental dynamics : an official publication of the American Association of Anatomists| PubMed ID: 23073844

2012
A physiological role for connective tissue growth factor in early wound healing.

Laboratory investigation; a journal of technical methods and pathology| PubMed ID: 23212098

2013
Onecut1 is essential for horizontal cell genesis and retinal integrity.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 23926259

2013
Advancements and challenges in generating accurate animal models of gestational diabetes mellitus.

American journal of physiology. Endocrinology and metabolism| PubMed ID: 24085033

2013
2014
2013
Loss of HNF6 expression correlates with human pancreatic cancer progression.

Laboratory investigation; a journal of technical methods and pathology| PubMed ID: 24638272

2014
Activated FoxM1 attenuates streptozotocin-mediated β-cell death.

Molecular endocrinology (Baltimore, Md.)| PubMed ID: 25073103

2014
2015
High-fat diet-induced β-cell proliferation occurs prior to insulin resistance in C57Bl/6J male mice.

American journal of physiology. Endocrinology and metabolism| PubMed ID: 25628421

2015
2015
2015
2015
2016
2016
2016
2016
2016
2016
2016
2016
2016
Onecut transcription factors in development and disease.

Trends in developmental biology| PubMed ID: 28018056

2016
Regulation of pancreatic β-cell function and mass dynamics by prostaglandin signaling.

Journal of cell communication and signaling| PubMed ID: 28132118

2017
2017
2018
2017
The liver.

Current biology : CB| PubMed ID: 29112863

2017
2018
2018
Developmental programming of the pancreatic islet by overnutrition.

Trends in developmental biology| PubMed ID: 29657386

2017
2018
2018
2019
2019
Regulation of the Pancreatic Exocrine Differentiation Program and Morphogenesis by Onecut 1/Hnf6.

Cellular and molecular gastroenterology and hepatology| PubMed ID: 30831323

2019
2019
2019
2019
2019
2019
Differential cell susceptibilities to Kras in the setting of obstructive chronic pancreatitis.

Cellular and molecular gastroenterology and hepatology| PubMed ID: 31310834

2019
The Beta Cell in Type 2 Diabetes.

Current diabetes reports| PubMed ID: 31399863

2019
2020
2020
2020
2021
2021
2021
2021
2021
2021
2021
2021
2021
2022
2022
2022
2022
2022
Developmental effects of metformin exposure.

Trends in developmental biology| PubMed ID: 36589485

2021
2023
2023
2023
2023
2023
2023
2024
2024
2024
Epigenetic modulation of cell fate during pancreas development.

Trends in developmental biology| PubMed ID: 38873037

2023
2024
A Developmental Approach to Mid-Career Faculty Leadership Training at Two Academic Medical Centers.

Journal of clinical psychology in medical settings| PubMed ID: 39306606

2024
2024