Hilary Ranson

Vector Biology, Liverpool School of Tropical Medicine

Affiliated withLiverpool School of Tropical Medicine liverpool school of tropical medicine

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2020

Other Publications

Article	Year
Evolution of supergene families associated with insecticide resistance. Science (New York, N.Y.)\| PubMed ID: 12364796	2002
Heterologous expression of four glutathione transferase genes genetically linked to a major insecticide-resistance locus from the malaria vector Anopheles gambiae. The Biochemical journal\| PubMed ID: 12718742	2003
Malaria parasite and vector genomes: partners in crime. Trends in parasitology\| PubMed ID: 12901937	2003
The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profiles. BMC genomics\| PubMed ID: 12914673	2003
An adult-specific CYP6 P450 gene is overexpressed in a pyrethroid-resistant strain of the malaria vector, Anopheles gambiae. Gene\| PubMed ID: 14585502	2003
The molecular basis of insecticide resistance in mosquitoes. Insect biochemistry and molecular biology\| PubMed ID: 15242706	2004
Characterization of the promoters of Epsilon glutathione transferases in the mosquito Anopheles gambiae and their response to oxidative stress. The Biochemical journal\| PubMed ID: 15631620	2005
The Anopheles gambiae detoxification chip: a highly specific microarray to study metabolic-based insecticide resistance in malaria vectors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15753317	2005
Elevated activity of an Epsilon class glutathione transferase confers DDT resistance in the dengue vector, Aedes aegypti. Insect biochemistry and molecular biology\| PubMed ID: 15944082	2005
An integrated genetic and physical map for the malaria vector Anopheles funestus. Genetics\| PubMed ID: 16143619	2005
Mosquito glutathione transferases. Methods in enzymology\| PubMed ID: 16399389	2005
Identification and analysis of single nucleotide polymorphisms (SNPs) in the mosquito Anopheles funestus, malaria vector. BMC genomics\| PubMed ID: 17204152	2007
Mapping a quantitative trait locus (QTL) conferring pyrethroid resistance in the African malaria vector Anopheles funestus. BMC genomics\| PubMed ID: 17261170	2007
Transcription profiling of a recently colonised pyrethroid resistant Anopheles gambiae strain from Ghana. BMC genomics\| PubMed ID: 17261191	2007
Detection of knockdown resistance (kdr) mutations in Anopheles gambiae: a comparison of two new high-throughput assays with existing methods. Malaria journal\| PubMed ID: 17697325	2007
The Aedes aegypti glutathione transferase family. Insect biochemistry and molecular biology\| PubMed ID: 17785190	2007
Genomic analysis of detoxification genes in the mosquito Aedes aegypti. Insect biochemistry and molecular biology\| PubMed ID: 18070670	2008
Pyrethroid tolerance is associated with elevated expression of antioxidants and agricultural practice in Anopheles arabiensis sampled from an area of cotton fields in Northern Cameroon. Molecular ecology\| PubMed ID: 18179425	2008
Characterization of knockdown resistance in DDT- and pyrethroid-resistant Culex quinquefasciatus populations from Sri Lanka. Tropical medicine & international health : TM & IH\| PubMed ID: 18312471	2008
Lessons from the past: managing insecticide resistance in malaria control and eradication programmes. The Lancet. Infectious diseases\| PubMed ID: 18374633	2008
Quantitative trait loci mapping of genome regions controlling permethrin resistance in the mosquito Aedes aegypti. Genetics\| PubMed ID: 18723882	2008
Development and application of a simple colorimetric assay reveals widespread distribution of sodium channel mutations in Thai populations of Aedes aegypti. Acta tropica\| PubMed ID: 18801327	2008
Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria. BMC genomics\| PubMed ID: 19014539	2008
Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids. PLoS genetics\| PubMed ID: 19043575	2008
Two duplicated P450 genes are associated with pyrethroid resistance in Anopheles funestus, a major malaria vector. Genome research\| PubMed ID: 19196725	2009
Recent rapid rise of a permethrin knock down resistance allele in Aedes aegypti in México. PLoS neglected tropical diseases\| PubMed ID: 19829709	2009
Exploring the molecular basis of insecticide resistance in the dengue vector Aedes aegypti: a case study in Martinique Island (French West Indies). BMC genomics\| PubMed ID: 19857255	2009
Insecticide resistance in Anopheles gambiae: data from the first year of a multi-country study highlight the extent of the problem. Malaria journal\| PubMed ID: 20015411	2009
Plasmodium infection alters Anopheles gambiae detoxification gene expression. BMC genomics\| PubMed ID: 20482856	2010
Transcriptomics and disease vector control. BMC biology\| PubMed ID: 20525113	2010
Pyrethroid resistance in Aedes aegypti from Grand Cayman. The American journal of tropical medicine and hygiene\| PubMed ID: 20682868	2010
A simple colorimetric assay for specific detection of glutathione-S transferase activity associated with DDT resistance in mosquitoes. PLoS neglected tropical diseases\| PubMed ID: 20824165	2010
Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control? Trends in parasitology\| PubMed ID: 20843745	2011
Mosquito age and susceptibility to insecticides. Transactions of the Royal Society of Tropical Medicine and Hygiene\| PubMed ID: 21353689	2011
Anopheles gambiae distribution and insecticide resistance in the cities of Douala and Yaoundé (Cameroon): influence of urban agriculture and pollution. Malaria journal\| PubMed ID: 21651761	2011
Extensive permethrin and DDT resistance in Anopheles arabiensis from eastern and central Sudan. Parasites & vectors\| PubMed ID: 21812972	2011
Dynamics of insecticide resistance in malaria vectors in Benin: first evidence of the presence of L1014S kdr mutation in Anopheles gambiae from West Africa. Malaria journal\| PubMed ID: 21910856	2011
Transcription of detoxification genes after permethrin selection in the mosquito Aedes aegypti. Insect molecular biology\| PubMed ID: 22032702	2012
Aging partially restores the efficacy of malaria vector control in insecticide-resistant populations of Anopheles gambiae s.l. from Burkina Faso. Malaria journal\| PubMed ID: 22269002	2012
Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression. The Journal of biological chemistry\| PubMed ID: 22282497	2012
Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22460795	2012
Footprints of positive selection associated with a mutation (N1575Y) in the voltage-gated sodium channel of Anopheles gambiae. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22493253	2012
Insecticide resistance in Culex quinquefasciatus from Zanzibar: implications for vector control programmes. Parasites & vectors\| PubMed ID: 22520274	2012
Detoxification enzymes associated with insecticide resistance in laboratory strains of Anopheles arabiensis of different geographic origin. Parasites & vectors\| PubMed ID: 22676389	2012
Gene amplification, ABC transporters and cytochrome P450s: unraveling the molecular basis of pyrethroid resistance in the dengue vector, Aedes aegypti. PLoS neglected tropical diseases\| PubMed ID: 22720108	2012
Three years of insecticide resistance monitoring in Anopheles gambiae in Burkina Faso: resistance on the rise? Malaria journal\| PubMed ID: 22799568	2012
Multiple-insecticide resistance in Anopheles gambiae mosquitoes, Southern Côte d'Ivoire. Emerging infectious diseases\| PubMed ID: 22932478	2012
Pyrethroid resistance in Anopheles gambiae, in Bomi County, Liberia, compromises malaria vector control. PloS one\| PubMed ID: 23028724	2012
Additional selection for insecticide resistance in urban malaria vectors: DDT resistance in Anopheles arabiensis from Bobo-Dioulasso, Burkina Faso. PloS one\| PubMed ID: 23049917	2012
Dissecting the mechanisms responsible for the multiple insecticide resistance phenotype in Anopheles gambiae s.s., M form, from Vallée du Kou, Burkina Faso. Gene\| PubMed ID: 23380570	2013
Identifying permethrin resistance loci in malaria vectors by genetic mapping. Parasitology\| PubMed ID: 23448678	2013
Temephos resistance in Aedes aegypti in Colombia compromises dengue vector control. PLoS neglected tropical diseases\| PubMed ID: 24069492	2013
Differential transcription profiles in Aedes aegypti detoxification genes after temephos selection. Insect molecular biology\| PubMed ID: 24299217	2014
The dynamics of pyrethroid resistance in Anopheles arabiensis from Zanzibar and an assessment of the underlying genetic basis. Parasites & vectors\| PubMed ID: 24314005	2013
Microarray and RNAi analysis of P450s in Anopheles gambiae male and female steroidogenic tissues: CYP307A1 is required for ecdysteroid synthesis. PloS one\| PubMed ID: 24324583	2013
Combining organophosphate treated wall linings and long-lasting insecticidal nets for improved control of pyrethroid resistant Anopheles gambiae. PloS one\| PubMed ID: 24409286	2014
A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector. Genome biology\| PubMed ID: 24565444	2014
CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae. PLoS genetics\| PubMed ID: 24651294	2014
Identification of carboxylesterase genes implicated in temephos resistance in the dengue vector Aedes aegypti. PLoS neglected tropical diseases\| PubMed ID: 24651719	2014
Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae. PloS one\| PubMed ID: 24675797	2014
The Sticky Resting Box, a new tool for studying resting behaviour of Afrotropical malaria vectors. Parasites & vectors\| PubMed ID: 24885432	2014
Insecticide resistance in Anopheles arabiensis in Sudan: temporal trends and underlying mechanisms. Parasites & vectors\| PubMed ID: 24886129	2014
Underpinning sustainable vector control through informed insecticide resistance management. PloS one\| PubMed ID: 24932861	2014
Molecular characterization of DDT resistance in Anopheles gambiae from Benin. Parasites & vectors\| PubMed ID: 25175167	2014
Increased pyrethroid resistance in malaria vectors and decreased bed net effectiveness, Burkina Faso. Emerging infectious diseases\| PubMed ID: 25279965	2014
Islands and stepping-stones: comparative population structure of Anopheles gambiae sensu stricto and Anopheles arabiensis in Tanzania and implications for the spread of insecticide resistanc... PloS one\| PubMed ID: 25353688	2014
Dissecting the organ specificity of insecticide resistance candidate genes in Anopheles gambiae: known and novel candidate genes. BMC genomics\| PubMed ID: 25421852	2014
Long-term trends in Anopheles gambiae insecticide resistance in Côte d'Ivoire. Parasites & vectors\| PubMed ID: 25429888	2014
Long-lasting insecticide-treated house screens and targeted treatment of productive breeding-sites for dengue vector control in Acapulco, Mexico. Transactions of the Royal Society of Tropical Medicine and Hygiene\| PubMed ID: 25604761	2015
The recent escalation in strength of pyrethroid resistance in Anopheles coluzzi in West Africa is linked to increased expression of multiple gene families. BMC genomics\| PubMed ID: 25766412	2015
The AvecNet Trial to assess whether addition of pyriproxyfen, an insect juvenile hormone mimic, to long-lasting insecticidal mosquito nets provides additional protection against clinical mal... Trials\| PubMed ID: 25873089	2015
Contrasting patterns of insecticide resistance and knockdown resistance (kdr) in the dengue vectors Aedes aegypti and Aedes albopictus from Malaysia. Parasites & vectors\| PubMed ID: 25888775	2015
To assess whether addition of pyriproxyfen to long-lasting insecticidal mosquito nets increases their durability compared to standard long-lasting insecticidal mosquito nets: study protocol ... Trials\| PubMed ID: 25927378	2015
When a discriminating dose assay is not enough: measuring the intensity of insecticide resistance in malaria vectors. Malaria journal\| PubMed ID: 25985896	2015
National malaria vector control policy: an analysis of the decision to scale-up larviciding in Nigeria. Health policy and planning\| PubMed ID: 26082391	2016
Electrostatic coating enhances bioavailability of insecticides and breaks pyrethroid resistance in mosquitoes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26324912	2015
Detection of G119S ace-1 (R) mutation in field-collected Anopheles gambiae mosquitoes using allele-specific loop-mediated isothermal amplification (AS-LAMP) method. Malaria journal\| PubMed ID: 26620269	2015
Insecticide Resistance in African Anopheles Mosquitoes: A Worsening Situation that Needs Urgent Action to Maintain Malaria Control. Trends in parasitology\| PubMed ID: 26826784	2016
Averting a malaria disaster: will insecticide resistance derail malaria control? Lancet (London, England)\| PubMed ID: 26880124	2016
Status of insecticide resistance in high-risk malaria provinces in Afghanistan. Malaria journal\| PubMed ID: 26888409	2016
An Operational Framework for Insecticide Resistance Management Planning. Emerging infectious diseases\| PubMed ID: 27089119	2016
Functional and immunohistochemical characterization of CCEae3a, a carboxylesterase associated with temephos resistance in the major arbovirus vectors Aedes aegypti and Ae. albopictus. Insect biochemistry and molecular biology\| PubMed ID: 27180726	2016
Spatial and Temporal Trends in Insecticide Resistance among Malaria Vectors in Chad Highlight the Importance of Continual Monitoring. PloS one\| PubMed ID: 27228026	2016
Delayed mortality effects cut the malaria transmission potential of insecticide-resistant mosquitoes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27402740	2016
Cytochrome P450 associated with insecticide resistance catalyzes cuticular hydrocarbon production in Anopheles gambiae. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27439866	2016
Challenges and opportunities associated with the introduction of next-generation long-lasting insecticidal nets for malaria control: a case study from Burkina Faso. Implementation science : IS\| PubMed ID: 27450082	2016
The impact of pyrethroid resistance on the efficacy and effectiveness of bednets for malaria control in Africa. eLife\| PubMed ID: 27547988	2016
Influence of the agrochemicals used for rice and vegetable cultivation on insecticide resistance in malaria vectors in southern Côte d'Ivoire. Malaria journal\| PubMed ID: 27553959	2016
Pyriproxyfen is metabolized by P450s associated with pyrethroid resistance in An. gambiae. Insect biochemistry and molecular biology\| PubMed ID: 27613592	2016
Fit for purpose: do we have the right tools to sustain NTD elimination? BMC proceedings\| PubMed ID: 28281703	2015
Current and Future Prospects for Preventing Malaria Transmission via the Use of Insecticides. Cold Spring Harbor perspectives in medicine\| PubMed ID: 28507193	2017
Corrigendum to "Functional and immunohistochemical characterization of CCEae3a, a carboxylesterase associated with temephos resistance in the major arbovirus vectors Aedes aegypti and Ae. al... Insect biochemistry and molecular biology\| PubMed ID: 28578775	2017
The transcription factor Maf-S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae. BMC genomics\| PubMed ID: 28854876	2017
House screening with insecticide-treated netting provides sustained reductions in domestic populations of Aedes aegypti in Merida, Mexico. PLoS neglected tropical diseases\| PubMed ID: 29543805	2018
Insecticide-resistant malaria vectors must be tackled. Lancet (London, England)\| PubMed ID: 29655495	2018
Efficacy of Olyset Duo, a bednet containing pyriproxyfen and permethrin, versus a permethrin-only net against clinical malaria in an area with highly pyrethroid-resistant vectors in rural Bu... Lancet (London, England)\| PubMed ID: 30104047	2018
Unexpectedly high Plasmodium sporozoite rate associated with low human blood index in Anopheles coluzzii from a LLIN-protected village in Burkina Faso. Scientific reports\| PubMed ID: 30143698	2018
Piperonyl butoxide (PBO) combined with pyrethroids in insecticide-treated nets to prevent malaria in Africa. The Cochrane database of systematic reviews\| PubMed ID: 30488945	2018
Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission. Malaria journal\| PubMed ID: 31068189	2019
A testing cascade to identify repurposed insecticides for next-generation vector control tools: screening a panel of chemistries with novel modes of action against a malaria vector. Gates open research\| PubMed ID: 31259317	2019
Mosquitoes cloak their legs to resist insecticides. Proceedings. Biological sciences\| PubMed ID: 31311476	2019
Characterisation of Anopheles strains used for laboratory screening of new vector control products. Parasites & vectors\| PubMed ID: 31690332	2019
Assessing the impact of the addition of pyriproxyfen on the durability of permethrin-treated bed nets in Burkina Faso: a compound-randomized controlled trial. Malaria journal\| PubMed ID: 31791332	2019
Barrier bednets target malaria vectors and expand the range of usable insecticides. Nature microbiology\| PubMed ID: 31792426	2020
Functional genetic validation of key genes conferring insecticide resistance in the major African malaria vector, . Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31801878	2019
A sensory appendage protein protects malaria vectors from pyrethroids. Nature\| PubMed ID: 31875852	2020
Anopheles gambiae populations from Burkina Faso show minimal delayed mortality after exposure to insecticide-treated nets. Parasites & vectors\| PubMed ID: 31924276	2020