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IR-TEx: An Open Source Data Integration Tool for Big Data Transcriptomics Designed for the Malaria Vector Anopheles gambiae
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Biology
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JoVE Journal Biology
IR-TEx: An Open Source Data Integration Tool for Big Data Transcriptomics Designed for the Malaria Vector Anopheles gambiae

IR-TEx: An Open Source Data Integration Tool for Big Data Transcriptomics Designed for the Malaria Vector Anopheles gambiae

DOI:
10.3791/60721-v

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08:22 min

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January 15, 2020

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, , , ,
1Vector Biology,Liverpool School of Tropical Medicine, 2Research Computing Unit,Liverpool School of Tropical Medicine, 3Department of Immunology and Infectious Diseases,Harvard T.H. Chan School of Public Health

Chapters

  • 00:04Title
  • 00:30Using the IR-TEx Web Application
  • 03:57Downloading and Implementing IR-TEx Locally
  • 04:52Modifying IR-TEx for use with Different Datasets
  • 06:05Results: Microsomal GST Contributes to Insecticide Resistance in Anopheles gambiae and Anopheles coluzzii Mosquitoes from Cte D Ivoire and Burkina Faso
  • 07:31Conclusion

Summary

Automatic Translation

Automatic Translation

IR-TEx explores insecticide resistance-related transcriptional profiles in the species Anopheles gambiae. Provided here are full instructions for using the application, modifications for exploring multiple transcriptomic datasets, and using the framework to build an interactive database for collections of transcriptomic data from any organism, generated in any platform.

Tags

Keywords: Data IntegrationTranscriptomicsAnopheles GambiaeIR-TExWeb ApplicationGene ExpressionInsecticide ResistancePyrethroidAnopheles ColuzziiFold ChangeAdjusted P-valueData Download

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